Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 18, 2011, Pages 5347-5352

  Taldone, Tony ^a   Gomes Dagama, Erica M ^a   Zong, Hongliang ^b   Sen, Siddhartha ^b   Alpaugh, Mary L ^a   Zatorska, Danuta ^a   Alonso Sabadell, Raul ^a   Guzman, Monica L ^b   Chiosis, Gabriela ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Flow cytometry; Fluorescence microscopy; Fluorescent Hsp90 inhibitor; PU H71; Purine

Indexed keywords

4 NITROBENZO[1,2,5]OXADIAZOLE; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; PU H 71; RED SHIFTED DYE SULFORHODAMINE 101; UNCLASSIFIED DRUG;

ARTICLE; CELL POPULATION; CHEMICAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL;

CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; FLOW CYTOMETRY; FLUORESCENT DYES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; PURINES; STEREOISOMERISM;

EID: 80051945455     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.026     Document Type: Article

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