Real-time 3D MRI of contrast agents in whole living mice

Contrast Media and Molecular Imaging

Volumn 6, Issue 4, 2011, Pages 275-281

  Bled, Emilie ^a   Hassen, Wadie Ben ^a   Pourtau, Line ^a   Mellet, Philippe ^a   Lanz, Titus ^b   Schüler, Dorothee ^b   Voisin, Pierre ^a   Franconi, Jean Michel ^a   Thiaudière, Eric ^a   Miraux, Sylvain ^a  

^a CNRS University Bordeaux Segalen   (France)

^b RAPID BIOMEDICAL GMBH   (Germany)

Author keywords

3D; Contrast agent; Mouse; MRI; Real time; Whole body

Indexed keywords

BOVINE SERUM ALBUMIN; GADOTERATE MEGLUMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTRAST ENHANCEMENT; DRUG DISTRIBUTION; ECHO PLANAR IMAGING; GLIOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL NOISE RATIO; THREE DIMENSIONAL IMAGING; WHOLE BODY MRI;

ANIMALS; CONTRAST MEDIA; FERRIC COMPOUNDS; GLIOMA; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MICE; MICE, NUDE; ORGANOMETALLIC COMPOUNDS;

EID: 80051925555     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.429     Document Type: Article

References (28)

1. Hatori A, Arai T, Yanamoto K, Yamasaki T, Kawamura K, Yui J, Konno F, Nakao R, Suzuki K, Zhang MR. Biodistribution and metabolism of the anti-influenza drug [11C]oseltamivir and its active metabolite [11C]Ro 64-0802 in mice. Nucl Med Biol 2009; 36: 47-55.
2. Willmann JK, Cheng Z, Davis C, Lutz AM, Schipper ML, Nielsen CH, Gambhir SS. Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice. Radiology 2008; 249: 212-219.
3. Franc BL, Acton PD, Mari C, Hasegawa BH. Small-animal SPECT and SPECT/CT: important tools for preclinical investigation. J Nucl Med 2008; 49: 1651-1663.
4. Figueroa SD, Winkelmann CT, Volkert WA, Hoffman TJ. Performance characteristics of an integrated small animal SPECT/CT unit. In 2005 IEEE Nuclear Science Symposium Conference Record, Yu B (ed.), Vol. 3 Piscataway, NJ: IEEE, 2005; 1752-1756.
5. Hwang AB, Hasegawa BH. Attenuation correction for small animal SPECT imaging using x-ray CT data. Med Phys 2005; 32: 2799-2780.
6. Kastis GA, Furenlid LR, Wilson DW, Peterson TE, Barber HB, Barrett HH. Compact CT/SPECT small-animal imaging system. IEEE Trans Nucl Sci 2004; 51: 63-67.
7. Lee HY, Li Z, Chen K, Hsu AR, Xu C, Xie J, Sun S, Chen X. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles. J Nucl Med 2008; 49: 1371-1379.
8. Catana C, Procissi D, Wu Y, Judenhofer MS, Qi J, Pichler BJ, Jacobs RE, Cherry SR. Simultaneous in vivo positron emission tomography and magnetic resonance imaging. Proc Natl Acad Sci USA 2008; 105: 3705-3710.
9. Heyn C, Ronald JA, Mackenzie LT, Macdonald IC, Chambers AF, Rutt BK, Foster PJ. In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn Reson Med 2006; 55: 23-29.
10. Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS, Yoneda T, MacDonald IC, Chambers AF, Rutt BK, Foster PJ. In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain. Magn Reson Med 2006; 56: 1001-1010.
11. Sosnovik DE, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol 2008; 103: 122-130.
12. van Vaals JJ, Brummer ME, Dixon WT, Tuithof HH, Engels H, Nelson RC, Gerety BM, Chezmar JL, den Boer JA. 'Keyhole' method for accelerating imaging of contrast agent uptake. J Magn Reson Imaging 1993; 3: 671-675.
13. Ribot EJ, Thiaudière E, Roulland R, Brugières P, Rahmouni A, Voisin P, Franconi JM, Miraux S. Application of MRI phase-difference mapping to assessment of vascular concentrations of BMS agent in mice. Contrast Media Mol Imag 2008; 3: 53-60.
14. 2*-measurement. Magn Reson Med 2009; 62: 672-681.
15. Kobayashi H, Kawamoto S, Choyke PL, Sato N, Knopp MV, Star RA, Waldmann TA, Tagaya Y, Brechbiel MW. Comparison of dendrimer-based macromolecular contrast agents for dynamic micro- magnetic resonance lymphangiography. Magn Reson Med 2003; 50: 758-766.
16. Wild JM, Woodrow J, van Beek EJ, Misselwitz B, Johnson R. Evaluation of rHA labeled with Gd-DTPA for blood pool imaging and targeted contrast delivery. Contrast Media Mol Imaging 2010; 5: 39-43.
17. Bousquet JC, Saini S, Stark DD, Hahn PF, Nigam M, Wittenberg J, Ferrucci JT Jr. Gd-DOTA: characterization of a new paramagnetic complex. Radiology 1988; 166: 693-698.
18. Geraldes CF, Sherry AD, Lázár I, Miseta A, Bogner P, Berenyi E, Sumegi B, Kiefer GE, McMillan K, Maton F, Muller RN. Relaxometry, animal biodistribution, and magnetic resonance imaging studies of some new gadolinium (III) macrocyclic phosphinate and phosphonate monoester complexes. Magn Reson Med 1993; 30: 696-703.
19. Bengele HH, Palmacci S, Rogers J, Jung CW, Crenshaw J, Josephson L. Biodistribution of an ultrasmall superparamagnetic iron oxide colloid, BMS 180549, by different routes of administration. Magn Reson Imag 1994; 12: 433-442.
20. Van Beers BE, Sempoux C, Materne R, Delos M, Smith AM. Biodistribution of ultrasmall iron oxide particles in the rat liver. J Magn Reson Imag 2001; 13: 594-599.
21. Majumdar S, Zoghbi SS, Gore JC. Pharmacokinetics of superparamagnetic iron-oxide MR contrast agents in the rat. Invest Radiol 1990; 25: 771-777.
22. Oksendal AN, Hals PA. Biodistribution and toxicity of MR imaging contrast media. J Magn Reson Imag 1993; 3: 157-165.
23. Gainkam LO, Huang L, Caveliers V, Keyaerts M, Hernot S, Vaneycken I, Vanhove C, Revets H, De Baetselier P, Lahoutte T. Comparison of the biodistribution and tumor targeting of two 99mTc-labeled anti- EGFR nanobodies in mice, using pinhole SPECT/micro-CT. J Nucl Med 2008; 49: 788-795.
24. Ribot EJ, Miraux S, Delville MH, Bouchaud V, Lacomme S, Gontier E, Bouzier-Sore AK, Franconi JM, Thiaudiere E, Voisin P. Study of the MR relaxation of microglia cells labeled with Gd-DTPA-bearing nanoparticles. Contrast Media Mol Imag 2009; 4: 109-117.
25. Oppelt A, Graumann R, Barfu H, Fischer H, Hartl W, Schajor W. FISP: a new fast MRI sequence. Electromedica 1986; 54: 15-18.
26. Vasanawala SS, Pauly JM, Nishimura DG. Linear combination steady-state free precession MRI. Magn Reson Med 2000; 43: 82-90.
27. Miraux S, Massot P, Ribot EJ, Franconi JM, Thiaudiere E. 3D TrueFISP imaging of mouse brain at 4.7T and 9.4T. J Magn Reson Imag 2008; 28: 497-503.
28. Miraux S, Calmettes G, Massot P, Lefrançois W, Parzy E, Muller B, Arsac LM, Deschodt-Arsac V, Franconi JM, Diolez P, Thiaudière E. 4D retrospective black blood trueFISP imaging of mouse heart. Magn Reson Med 2009; 62: 1099-1105.