Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability

Journal of Biological Chemistry

Volumn 286, Issue 34, 2011, Pages 29709-29717

  Jensen, Jan K ^a   Thompson, Lawrence C ^b   Bucci, Joel C ^b   Nissen, Poul ^a   Gettins, Peter G W ^c   Peterson, Cynthia B ^b   Andreasen, Peter A ^a   Morth, J Preben ^a,c,d  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF TENNESSEE   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE STATE; COFACTORS; CONFORMATIONAL INSTABILITY; HUMAN CANCER; PATHOLOGICAL CONDITIONS; PHYSIOLOGICAL REGULATORS; PLASMINOGEN ACTIVATOR INHIBITOR-1; RAPID CONVERSION; STABILIZING EFFECTS; STRUCTURAL CHANGE; STRUCTURAL COMPARISON; STRUCTURAL INFORMATION; TISSUE REMODELING; VITRONECTIN; WILD TYPES;

CHLORINE; CHLORINE COMPOUNDS; CONFORMATIONS; TISSUE;

CRYSTAL STRUCTURE;

CHLORIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; VITRONECTIN;

ARTICLE; ARTIFACT; BETA SHEET; BINDING SITE; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS; WILD TYPE;

CRYSTALLOGRAPHY, X-RAY; HUMANS; MUTATION, MISSENSE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

EID: 80051925341     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.236554     Document Type: Article

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