Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon

Phytomedicine

Volumn 18, Issue 11, 2011, Pages 998-1005

  Yang, Jiaming ^a   Ip, Paul S P ^a   Yeung, John H K ^a   Che, Chun Tao ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Colonic smooth muscle; Enteric nervous system; Nitric oxide; Non adrenergic non cholinergic relaxation; Schisandra chinensis; Schisandrin

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE TRIPHOSPHATE; APAMIN; ATROPINE; CHYMOTRYPSIN; CICAPROST; GUANYLATE CYCLASE INHIBITOR; ISOPRENALINE; NICOTINE; NITRIC OXIDE; PHENTOLAMINE; PHENYLEPHRINE; PROPRANOLOL; PURINERGIC P2 RECEPTOR ANTAGONIST; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SCHIZANDRIN; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; COLON MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; INTESTINE CONTRACTION; MALE; MUSCLE RELAXATION; NERVE CELL INHIBITION; NONADRENERGIC NONCHOLINERGIC NERVE; NONHUMAN; PRIORITY JOURNAL; RAT; SCHISANDRACEAE;

ADRENERGIC ANTAGONISTS; ANIMALS; ATROPINE; BENZYL COMPOUNDS; COLON, ASCENDING; CYCLIC GMP; CYCLOOCTANES; ENZYME INHIBITORS; IMIDAZOLES; LIGNANS; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; NITRIC OXIDE; PHENTOLAMINE; PLANT EXTRACTS; POLYCYCLIC COMPOUNDS; PROPRANOLOL; PURINERGIC ANTAGONISTS; PYRIDOXAL PHOSPHATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, EPOPROSTENOL; SCHISANDRA; TETRODOTOXIN; XANTHINES;

RATTUS; SCHISANDRA CHINENSIS;

EID: 80051901651     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.02.014     Document Type: Article

References (33)

1. A. Belai, and G. Burnstock Evidence for coexistence of ATP and nitric oxide in non-adrenergic, non-cholinergic (NANC) inhibitory neurons in the rat ileum, colon and anococcygeus muscle Cell Tissue Res. 278 1994 197 200 (Pubitemid 24281917)
2. R. Benkó, S. Undi, M. Wolf, A. Vereczkei, L. Illényi, M. Kassai, L. Cseke, D. Kelemen, Ö.P. Horvath, A. Antal, K. Magyar, and L. Barthó P2 purinoceptor antagonists inhibit the non-adrenergic, non-cholinergic relaxation of the human colon in vitro Neuroscience 147 2007 146 152 (Pubitemid 46873853)
3. K.R. Bley, A. Bhattacharya, D.V. Daniels, J. Gever, A. Jahangir, C. O'Yang, S. Smith, D. Srinivasan, P.D.W. Ford Anthony, and M.F. Jett RO1138452 and RO3244794: characterization of structurally distinct, potent and selective prostacyclin receptor antagonists Br. J. Pharmacol. 147 2006 335 345 (Pubitemid 43214691)
4. G. Burnstock The journey to establish purinergic signalling in the gut. Neurogastroenterology and motility Eur. J. Pharmacol. 20 2008 8 19 (Pubitemid 351514536)
5. I. Dhaese, G. Vanneste, P. Sips, E. Buys, P. Brouckaert, and R.A. Lefebvre Involvement of soluble guanylate cyclas α1 and α2, and SKCa channels in NANC relaxation of mouse distal colon Eur. J. Pharmacol. 589 2008 251 259
6. M.S. Faussone-Pellegrini Histogenesis, structure and relationships of interstitial cells of Cajal (ICC): from morphology to functional interpretation Eur. J. Morphol. 30 1992 137 148
7. A.E. Foxx-Orenstein, and J.R. Grider Regulation of colonic propulsion by enteric excitatory and inhibitory neurotransmitters Am. J. Physiol. Gastrointest. Liver Physiol. 271 1996 433 437
8. A. Friebe, and D. Koesling Regulation of nitric oxide-sensitive guanylyl cyclase Circ. Res. 93 2003 96 105 (Pubitemid 36919696)
9. J.R. Grider, K.S. Murthy, J.G. Jin, and G.M. Makhlouf Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release Am. J. Physiol. Gastrointest. Liver Physiol. 262 1992 774 778
10. C.W. Halstead, S. Lee, C.S. Khoo, J.R. Hennell, and A. Bensoussan Validation of a method for the simultaneous determination of four schisandra lignans in the raw herb and commercial dried aqueous extracts of Schisandra chinensis (Wu Wei Zi) by RP-LC with DAD J. Pharm. Biomed. Anal. 45 2007 30 37 (Pubitemid 47374996)
11. A. Huber, D. Saur, M. Kurjak, V. Schusdziarra, and H.D. Allescher Characterization and splice variants of neuronal nitric oxide synthase in rat small intestine Am. J. Physiol. Gastrointest. Liver Physiol. 275 1998 1146 1156
12. J.D. Huizinga, I. Berezin, E.E. Daniel, and E. Chow Inhibitory innervation of colonic smooth muscle cells and interstitial cells of Cajal Can. J. Physiol. Pharmacol. 68 1990 447 454 (Pubitemid 20130612)
13. S.P. Ip, D.H.E. Mak, P.C. Li, M.K.T. Poon, and K.M. Ko Effect of a lignan-enriched extract of Schisandra chinensis on aflatoxin b1 and cadmium chloride-induced hepatotoxicity in rats Pharmacol. Toxicol. 78 1996 413 416 (Pubitemid 26226654)
14. M. Kishi, T. Takeuchi, N. Suthamnatpong, T. Ishii, H. Nishio, F. Hata, and T. Takewaki VIP- and PACAP-mediated nonadrenergic, noncholinergic inhibition in longitudinal muscle of rat distal colon: involvement of activation of charybdotoxin- and apamin-sensitive K+ channels Br. J. Pharmacol. 119 1996 623 630 (Pubitemid 26356573)
15. J.W. Konturek, P. Thor, A. Lukaszyk, A. Gabryelewicz, S.J. Konturek, and W. Domschke Endogenous nitric oxide in the control of esophageal motility in humans J. Physiol. Pharmacol. 48 1997 201 209 (Pubitemid 27305520)
16. 2+ channels coupled to VIP release and NO synthesis in enteric synaptosomes Am. J. Physiol. Gastrointest. Liver Physiol. 283 2002 1027 1034
17. C.A. Maggi, and S. Giulani Multiple inhibitory mechanisms mediate non-adrenergic non-cholinergic relaxation in the circular muscle of the guinea-pig colon Naunyn-Schmiedeberg's Arch. Pharmacol. 347 1993 630 634 (Pubitemid 23181417)
18. Y. Mizuta, T. Takahashi, and C. Owyang Nitrergic regulation of colonic transit in rats Am. J. Physiol. Gastrointest. Liver Physiol. 277 1999 275 279
19. F. Mule, and R. Serio NANC inhibitory neurotransmission in mouse isolated stomach: involvement of nitric oxide, ATP and vasoactive intestinal polypeptide Br. J. Pharmacol. 140 2003 31 437
20. National Committee of Chinese Pharmacopoeia Pharmacopoeia of the People's Republic of China 2005 Chemical Industry Press Beijing pp. 44-45
21. L. Opletal, H. Sovova, and M. Bartlova Dibenzo[a,c]cyclooctadiene lignans of the genus Schisandra importance, isolation and determination J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 812 2004 357 371 (Pubitemid 39535421)
22. S.Y. Pan, H. Dong, X.Y. Zhao, C.J. Xiang, H.Y. Fang, W.F. Fong, Z.L. Yu, and K.M. Ko Schisandrin B from Schisandra chinensis reduces hepatic lipid contents in hypercholesterolaemic mice J. Pharm. Pharmacol. 60 2008 399 403 (Pubitemid 351269829)
23. A. Panossian, and G. Wikman Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine J. Ethnopharmacol. 118 2008 183 212
24. J.Y. Park, S.J. Lee, M.R. Yun, K.W. Seo, S.S. Bae, J.W. Park, Y.J. Lee, W.J. Shin, Y.W. Choi, and C.D. Kim Gomisin A from Schisandra chinensis induces endothelium-dependent and direct relaxation in rat thoracic aorta Planta Med. 73 2007 1537 1542
25. J.Y. Park, H.K. Shin, Y.J. Lee, Y.W. Choi, S.S. Bae, and C.D. Kim The mechanism of vasorelaxation induced by Schisandra chinensis extract in rat thoracic aorta J. Ethnopharmacol. 121 2009 69 73
26. L. Pluja, E. Fernandez, and M. Jimenez Neural modulation of the cyclic electrical and mechanical activity in the rat colonic circular muscle: putative role of ATP and NO Br. J. Pharmacol. 126 1999 883 892 (Pubitemid 29103704)
27. M.R. Rhyu, E.-Y. Kim, B.-K. Yoon, Y.J. Lee, and S.-N. Chen Aqueous extract of Schizandra chinensis fruit causes endothelium-dependent and -independent relaxation of isolated rat thoracic aorta Phytomedicine 13 2006 651 657 (Pubitemid 44755119)
28. B. Rózsai, Z. Lázár, R. Benkó, and L. Barthó Inhibition of the NANC relaxation of the Guinea-pig proximal colon longitudinal muscle by the purinoceptor antagonist PPADS, inhibition of nitric oxide synthase, but not by a PACAP/VIP antagonist Pharmacol. Res. 43 2001 83 87 (Pubitemid 32577759)
29. S.K. Sarna Nitronergic regulation of gastric motility and emptying Curr. Opin. Gastroenterol. 12 1996 512 516 (Pubitemid 26402501)
30. M. Schemann Control of gastrointestinal motility by the "gut brain" - the enteric nervous system J. Pediatr. Gastroenterol. Nutr. 41 2005 4 6
31. M. Suekawa, T. Shiga, H. Sone, Y. Ikeya, H. Taguchi, M. Aburada, and E. Hosoya Effects of gomisin J and analogous lignan compounds in schisandra fruits on isolated smooth muscles Yakugaku Zasshi. 107 1987 720 726 (Pubitemid 18075339)
32. N. Suthamnatpong, M. Hosokawa, T. Takeuchi, F. Tata, and T. Takewaki Nitric oxide-mediated inhibitory response of rat proximal colon: independence from changes in membrane potential Br. J. Pharmacol. 112 1994 676 682 (Pubitemid 24172919)
33. S.M. Ward, H.H. Dalziel, M.E. Bradley, I.L.O. Buxton, K. Keef, D.P. Westfall, and K.M. Sanders Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon Br. J. Pharmacol. 107 1992 1075 1082