Abnormal methylation patterns at the IGF2/H19 imprinting control region in phenotypically normal babies conceived by assisted reproductive technologies

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 158, Issue 1, 2011, Pages 52-55

  Shi, Xiaoyun ^a   Ni, Yunping ^a   Zheng, Haiyan ^a   Chen, Shiling ^a   Zhong, Mei ^a   Wu, Fangrong ^a   Xia, Rong ^a   Luo, Yanqun ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Assisted reproductive technologies (ART); DNA methylation; IGF2 H19; Imprinted genes; Imprinting control region (ICR)

Indexed keywords

RNA H19;

ARTICLE; COMBINED BISULFITE RESTRICTION ANALYSIS; CONTROLLED STUDY; DIZYGOTIC TWINS; DNA METHYLATION; EMBRYO CULTURE; FERTILIZATION IN VITRO; GAMETE; GENE EXPRESSION; GENETIC ANALYSIS; GENOME IMPRINTING; HUMAN; HUMAN TISSUE; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; NEWBORN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 80051900786     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2011.04.001     Document Type: Article

References (15)

1. C.M. Williamson, M.D. Turner, and S.T. Ball Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster Nat Genet 38 2006 350 355
2. P. Arnaud, and R. Feil Epigenetic deregulation of genomic imprinting in human disorders and following assisted reproduction Birth Defects Res C Embryo Today 75 2005 81 97 (Pubitemid 41153674)
3. H. Nakagawa, R.B. Chadwick, P. Peltomaki, C. Plass, Y. Nakamura, and A. de La Chapelle Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer Proc Natl Acad Sci USA 98 2001 591 596 (Pubitemid 32105087)
4. G.A. Ulaner, T.H. Vu, and T. Li Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site Hum Mol Genet 12 2003 535 549 (Pubitemid 36305592)
5. J. Bliek, S.M. Maas, and J.M. Ruijter Increased tumour risk for BWS patients correlates with aberrant H19 and not KCNQ1OT1 methylation: occurrence of KCNQ1OT1 hypomethylation in familial cases of BWS Hum Mol Genet 10 2001 467 476 (Pubitemid 32181669)
6. C. Gicquel, S. Rossignol, and S. Cabrol Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome Nat Genet 37 2005 1003 1007 (Pubitemid 43086160)
7. M. Ludwig, A. Katalinic, S. Gross, A. Sutcliffe, R. Varon, and B. Horsthemke Increased prevalence of imprinting defects in patients with Angelman syndrome born to subfertile couples J Med Genet 42 2005 289 291 (Pubitemid 40523949)
8. E.R. Maher, L.A. Brueton, and S.C. Bowdin Beckwith-Wiedemann syndrome and assisted reproduction technology (ART) J Med Genet 40 2003 62 64 (Pubitemid 36115128)
9. P. Fauque, P. Jouannet, and C. Lesaffre Assisted reproductive technology affects developmental kinetics, H19 imprinting control region methylation and H19 gene expression in individual mouse embryos BMC Dev Biol 7 2007 116
10. A. Sato, E. Otsu, H. Negishi, T. Utsunomiya, and T. Arima Aberrant DNA methylation of imprinted loci in superovulated oocytes Hum Reprod 22 2007 26 35 (Pubitemid 44942663)
11. T.I. Leakey, J. Zielinski, R.N. Siegfried, E.R. Siegel, C.Y. Fan, and C.A. Cooney A simple algorithm for quantifying DNA methylation levels on multiple independent CpG sites in bisulfite genomic sequencing electropherograms Nucleic Acids Res 36 2008 e64
12. C.J. Marques, P. Costa, and B. Vaz Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia Mol Hum Reprod 14 2008 67 74
13. H. Kobayashi, A. Sato, and E. Otsu Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients Hum Mol Genet 16 2007 2542 2551 (Pubitemid 47617721)
14. H. Kobayashi, H. Hiura, and R.M. John DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm Eur J Hum Genet 2009
15. M.V. Gomes, J. Huber, R.A. Ferriani, N.A. Amaral, and E.S. Ramos Abnormal methylation at the KvDMR1 imprinting control region in clinically normal children conceived by assisted reproductive technologies Mol Hum Reprod 15 2009 471 477