An operational research approach to identify cardiac surgery patients at risk of severe post-operative bleeding

Health Care Management Science

Volumn 14, Issue 3, 2011, Pages 215-222

  Reddy, Brian ^a,c   Pagel, Christina ^a   Vuylsteke, Alain ^b   Gerrard, Caroline ^b   Nashef, Sam ^b   Utley, Martin ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b PAPWORTH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cardiac surgery; Intensive care; Risk model

Indexed keywords

ARTICLE; BODY WEIGHT; HEART SURGERY; HUMAN; POSTOPERATIVE HEMORRHAGE; RISK ASSESSMENT; RISK FACTOR; SYSTEM ANALYSIS; THEORETICAL MODEL;

BODY WEIGHT; CARDIAC SURGICAL PROCEDURES; HUMANS; MODELS, THEORETICAL; OPERATIONS RESEARCH; POSTOPERATIVE HEMORRHAGE; RISK ASSESSMENT; RISK FACTORS;

EID: 80051893008     PISSN: 13869620     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10729-011-9152-0     Document Type: Article

References (22)

1. Unsworth-White MJ, Herriot A, Valencia O, Poloniecki J, Smith EE, Murday AJ, Parker DJ, Treasure T (1995) Resternotomy for bleeding after cardiac operation: a marker for increased morbidity and mortality. Ann Thorac Surg 59(3): 664-667.
2. Karkouti K, Wijeysundera DN, Yau TM, Beattie WS, Abdelnaem E, McCluskey SA, Ghannam M, Yeo E, Djaiani G, Karski J (2004) The independent association of massive blood loss with mortality in cardiac surgery. Transfusion 44(10): 1453-1462.
3. Dacey LJ, Munoz JJ, Baribeau YR, Johnson ER, Lahey SJ, Leavitt BJ, Quinn RD, Nugent WC, Birkmeyer JD, O'Connor GT (1998) Reexploration for haemorrhage following coronary artery bypass grafting. Incidence and risk factors. Arch Surg 133(4): 442-447.
4. Hall TS, Brevetti GR, Skoultchi AJ, Sines JC, Gregory P, Spotnitz AJ (2001) Re-exploration for hemorrhage following open heart surgery differentiation on the causes of bleeding and the impact on patient outcomes. Ann Thorac Cardiovasc Surg 7(6): 352-357.
5. Koch CG, Li L, Duncan AI, Mihaljevic T, Loop FD, Starr NJ, Blackstone EH (2006) Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg 81(5): 1650-1657.
6. Murphy GJ, Reeves BC, Rogers CA, Rizvi SIA, Culliford L, Angelini GD (2007) Increased mortality, post-operative morbidity and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 116(22): 2544-2552.
7. Despotis GJ, Filos KS, Zoys TN, Hogue CW Jr, Spitznagel E, Lappas DG (1996) Factors associated with excessive post-operative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients. Anesth Analg 82(1): 13-21.
8. Karthik S, Grayson AD, McCarron EE, Pullan DM, Desmond MJ (2004) Reexploration for bleeding after coronary artery bypass surgery: risk factors, outcomes, and the effect of time delay. Ann Thorac Surg 78: 527-534.
9. Ferraris VA, Gildenforin V (1989) Predictors of excessive blood use after coronary artery bypass grafting. A multivariate analysis. J Thorac Cardivasc Surg 98(4): 492-497.
10. Karkouti K, O'Farrell R, Yau TM, Beattie WS (2006) Prediction of massive blood transfusion in cardiac surgery. Can J Anesth 53(8): 781-794.
11. Rivera JJ, Iribarren JL, Raya JM, Nassar I, Lorente L, Perez R, Brouard M, Lorenzo JM, Garrido P, Barrios Y, Diaz M, Alarco B, Martinez R, Mora ML (2007) Factors associated with excessive bleeding in cardiopulmonary bypass patients: a nested case-control study. J Cardiothorac Surg 2: 17-26.
12. Mora Mangano CT, Neville MJ, Hsu PH, Mignea I, King J, Miller DC (2001) Aprotinin, blood loss, and renal dysfunction in deep hypothermic circulatory arrest. Circulation 104(Suppl I): 276-281.
13. Mangano DT, Tudor IC, Dietzel C, Multicenter Study of Perioperative Ischemia Research Group, Ischemia Research and Education Foundation (2006) The risk associated with aprotinin in cardiac surgery. N Engl J Med 354(4): 353-365.
14. Karkouti K, Wijeysundera DN, Yau TM, McCluskey SA, Tait G, Beattie WS (2010) The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. Anesth Analg 110(1): 21-29.
15. Despotis GJ, SKubas NJ, Goodnough LT (1999) Optimal management of bleeding and transfusion in patients undergoing cardiac surgery. Semin Thorac Cardiovasc Surg 11(2): 84-104.
16. Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R (1999) European system for cardiac operative risk evaluation [EuroSCORE]. Eur J Cardiothorac Surg 16(1): 9-13.
17. Vuylsteke A, Pagel C, Gerrard C, Reddy B, Nashef F, Aldam P, Utley M (2010) The Papworth Bleeding Risk Score: a stratification scheme for identifying cardiac surgery patients at risk of excessive early postoperative bleeding. Eur J Cardiothorac Surg. doi: 10. 1016/j. ejcts. 2010. 10. 003.
18. Despotis GJ, Avidan MS, Hogue Jr (2001) Mechanisms and attenuation of haemostatic activation during extracorporeal circulation. Ann Thorac Surg 72: S1821-S1831.
19. Parr KG, Patel MA, Dekker R, Levin R, Glynn R, Avorn J, Morse DS (2003) Multivariate predictors of blood product use in cardiac surgery. J Cardiothorac Vasc Anesth 17(2): 176-178.
20. Karkouki K, Cohen MM, McCluskey SA, Sher GD (2001) A multivariate model for predicting the need for blood transfusion in patients undergoing first time elective coronary bypass graft surgery. Transfusion 41(10): 1193-1203.
21. Physical Status: The use and interpretation of anthropometry. Report of a WHO expert committee. WHO technical report series 854. Geneva: World Health Organization, 1995.
22. Sedrakyan A, Treasure T, Elefteriades JA (2004) Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials. J Thorac Cardiovasc Surg 128(3): 442-448.