The Papworth Bleeding Risk Score: A stratification scheme for identifying cardiac surgery patients at risk of excessive early postoperative bleeding

European Journal of Cardio-thoracic Surgery

Volumn 39, Issue 6, 2011, Pages 924-930

  Vuylsteke, Alain ^a   Pagel, Christina ^b   Gerrard, Caroline ^a   Reddy, Brian ^b   Nashef, Samer ^a   Aldam, Poppy ^a   Utley, Martin ^b  

^a PAPWORTH HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiopulmonary bypass; Haemorrhage; Predictive scoring; Surgery

Indexed keywords

APROTININ; FRESH FROZEN PLASMA; TRANEXAMIC ACID;

ADVERSE OUTCOME; AGE; AORTA VALVE DISEASE; ARTICLE; BODY MASS; CARDIOPULMONARY BYPASS; CLINICAL DECISION MAKING; CLINICAL FEATURE; CONFIDENCE INTERVAL; CORONARY ARTERY BYPASS GRAFT; CRYOPRECIPITATE; DATA BASE; EMERGENCY SURGERY; HEART SURGERY; HEART VALVE SURGERY; HIGH RISK PATIENT; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; PAPWORTH BLEEDING RISK SCORE; PATIENT ASSESSMENT; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; RISK REDUCTION; SCORING SYSTEM; SURGICAL PATIENT; THROMBOCYTE TRANSFUSION;

AGE FACTORS; AGED; ANTIFIBRINOLYTIC AGENTS; BLOOD TRANSFUSION; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; DRUG UTILIZATION; ENGLAND; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; MALE; POSTOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE CARE; REOPERATION; RISK ASSESSMENT;

EID: 79955619448     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2010.10.003     Document Type: Article

References (25)

1. Unsworth-White M.J., Herriot A., Valencia O., Poloniecki J., Smith E.E., Murday A.J., Parker D.J., Treasure T. Resternotomy for bleeding after cardiac operation: a marker for increased morbidity and mortality. Ann Thorac Surg 1995, 59:664-667.
2. Karkouti K., Wijeysundera D.N., Yau T.M., Beattie W.S., Abdelnaem E., McCluskey S.A., Ghannam M., Yeo E., Djaiani G., Karski J. The independent association of massive blood loss with mortality in cardiac surgery. Transfusion 2004, 44:1453-1462.
3. Murphy G.J., Reeves B.C., Rogers C.A., Rizvi S.I.A., Culliford L., Angelini G.D. Increased mortality, post-operative morbidity and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 2007, 116:2544-2552.
4. Despotis G.J., Filos K.S., Zoys T.N., Hogue C.W., Spitznagel E., Lappas D.G. Factors associated with excessive post-operative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients. Anesth Analg 1996, 82:13-21.
5. Karthik S., Grayson A.D., McCarron E.E., Pullan D.M., Desmond M.J. Reexploration for bleeding after coronary artery bypass surgery: risk factors, outcomes, and the effect of time delay. Ann Thorac Surg 2004, 78:527-534.
6. Ferraris V.A., Gildenforin V. Predictors of excessive blood use after coronary artery bypass grafting. A multivariate analysis. J Thorac Cardiovasc Surg 1989, 98:492-497.
7. Karkouti K., O'Farrell R., Yau T.M., Beattie W.S. Prediction of massive blood transfusion in cardiac surgery. Can J Anesth 2006, 53:781-794.
8. Gill R., Herbertson M., Vuylsteke A., Olsen P.S., von Heymann C., Mythen M., Sellke F., Booth F., Schmidt T.A. Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery. Circulation 2009, 120:21-27.
9. Mangano D.T., Tudor I.C., Dietzel C. The risk associated with aprotinin in cardiac surgery. N Engl J Med 2006, 354:353-365. Multicenter Study of Perioperative Ischemia Research Group; Ischemia Research and Education Foundation.
10. Karkouti K., Wijeysundera D.N., Yau T.M., McCluskey S.A., Tait G., Beattie W.S. The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. Anesth Analg 2010, 110:21-29.
11. Nashef S.A., Roques F., Michel P., Gauducheau E., Lemeshow S., Salamon R. European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 1999, 16:9-13.
12. Physical Status: the use and interpretation of anthropometry. Report of a WHO expert committee. WHO technical report series 854. Geneva: World Health Organization; 1995.
13. Belisle S., Hardy J.F. Haemorrhage and the use of blood products after adult cardiac operations: myths and realities. Ann Thorac Surg 1996, 62:1908-1917.
14. Murphy G., Angelini G. Indications for blood transfusion in cardiac surgery. Ann Thorac Surg 2006, 82:2323-2334.
15. Moulton M.J., Creswell L.L., Mackey M.E., Cox J.L., Rosenbloom M. Reexploration for bleeding is a risk for adverse outcomes after cardiac operations. J Thorac Cardiovasc Surg 1996, 111:1037-1046.
16. Parr K.G., Patel M.A., Dekker R., Levin R., Glynn R., Avorn J., Morse D.S. Multivariate predictors of blood product use in cardiac surgery. J Cardiothorac Vasc Anesth 2003, 17:176-178.
17. Loudon B., Smith M.P. Recombinant factor VIIa as an adjunctive therapy for patients requiring large volume transfusion: a pharmacoeconomic evaluation. Intern Med J 2005, 35:463-467.
18. O'Connell K.A., Wood J.J., Wise R.P., Lozier J.N., Braun M.M. Thromboembolic adverse events after use of recombinant human coagulation factor VIIa. JAMA 2006, 295:293-298.
19. Whitlock R., Crowther M.A., Ng H.L. Bleeding in cardiac surgery: its prevention and treatment - an evidence based review. Crit Care Clin 2005, 21:589-610.
20. Kuepper F., Dangas G., Mueller-Chorus A., Kulka P.M., Zenz M., Wiebalck A. Fibrinolytic activity and bleeding after cardiac surgery with cardiopulmonary bypass and low dose aprotinin therapy. Blood Coagul Fibrinolysis 2003, 14:147-153.
21. Szefner J. Preventing and managing post-operative bleeding in cardiac surgery by controlling disseminated intravascular coagulation. Eur J Anaesthesiol 2007, 24:59-66.
22. Hall T.S., Brevetti G.R., Skoultchi A.J., Sines J.C., Gregory P., Spotnitz A.J. Re-exploration for hemorrhage following open heart surgery differentiation on the causes of bleeding and the impact on patient outcomes. Ann Thorac Cardiovasc Surg 2001, 7:352-357.
23. Dial S., Delabays E., Albert M., Gonzalez A., Camarda J., Law A., Menzies D. Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass. J Thorac Cardiovasc Surg 2005, 130:654-661.
24. Karkouki K., Cohen M.M., McCluskey S.A., Sher G.D. A multivariate model for predicting the need for blood transfusion in patients undergoing first time elective coronary bypass graft surgery. Transfusion 2001, 41:1193-1203.
25. Rawn J.D. Blood transfusion in cardiac surgery - a silent epidemic revisited. Circulation 2007, 116:2523-2524.