In situ observation of dynamic behavior of liver cells to carbon nanotubes and analysis of cell functions

Nano Biomedicine

Volumn 1, Issue 2, 2009, Pages 95-108

  Itoh, Sachiko ^a   Taira, Toshio ^b   Yawaka, Yasutaka ^a   Watari, Fumio ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Primary Cell Co Ltd   (Japan)

Author keywords

Carbon nanotubes; Hepatocyte; In situ observation; Inflammation; Phagocytosis

Indexed keywords

ACUTE TOXICITY; BIOLOGICAL ORGANISMS; CELL ACTIVITY; CELL FUNCTIONS; CULTURE MEDIUM; CYTOKINES; DOSE-DEPENDENT MANNER; DYNAMIC BEHAVIORS; FOREIGN OBJECT; HEPATOCYTES; HUMAN HEPATOCYTES; IN SITU OBSERVATION; IN-SITU OBSERVATIONS; INFLAMMATION; LIVER CELLS; PHAGOCYTOSIS; REACTION BEHAVIOR; SUPEROXIDE DISMUTASE ACTIVITIES; TEM (TRANSMISSION ELECTRON MICROSCOPY);

ANTIGEN-ANTIBODY REACTIONS; BODY FLUIDS; CARBON NANOTUBES; CELL CULTURE; CELL DEATH; DEBRIS; OPTICAL MICROSCOPY; OXYGEN; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

BEHAVIORAL RESEARCH;

EID: 80051872491     PISSN: 18835198     EISSN: 21854734     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Lin Y, Taylor S, Li HP, Fernando KAS, Qu LW, Wang W, Gu LR, Zhou B, Sun YP. Advances toward bioapplications of carbon nanotubes. J Mater Chem 2004;14:527-541.
2. De Jong WH, Borm PJ. Drug delivery and nanoparticles:applications and hazards. Int J Nanomedicine 2008;3:133-149.
3. Pantarotto D, Singh R, McCarthy D, Erhardt, Briand JP, Prato M, Kostarelos K, Bianco A. Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew Chem Int Ed Engl 2004;43:5242-5246. (Pubitemid 39382552)
4. Harrison BS, Atala A. Carbon nanotube applications for tissue engineering. Biomaterials 2007;28:344-353. (Pubitemid 44537381)
5. Aoki N, Akasaka T, Watari F, Yokoyama A. Carbon nanotubes as scaffolds for cell and effect on cellular functions. Dent Mater J 2007;26:178-185.
6. Terada M, Abe S, Akasaka T, Uo M, Kitagawa Y, Watari F. Development of a multiwalled carbon nanotube coated collagen dish. Dent Mater J 2009;28:82-88.
7. Zanello LP, Zhao B, Hu H, Haddon RC. Bone cell proliferation on carbon nanotubes. Nano Lett 2006;6:562-567.
8. Mooney E, Dockery P, Greiser U, Murphy M, Barron V. Carbon nanotubes and mesenchymal stem cells: biocompatibility, proliferation and differentiation. Nano Lett 2008;8:2137-2143.
9. Shi Kam NW, Jessop TC, Wender PA, Dai H. Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells. J Am Chem Soc 2004;126:6850-6851. (Pubitemid 38855367)
10. Monteiro-Riviere NA, Nemanich RJ, Inman AO, Wang YY, Riviere JE. Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 2005;155:377-384. (Pubitemid 40093001)
11. Wu W, Wieckowski S, Pastorin G, Benincasa M, Klumpp C, Briand JP, Gennaro R, Prato M, Bianco A. Targeted delivery of amphotericin B to cells by using functionalized carbon nanotubes. Angew Chem Int Ed Engl 2005;44:6358-6362. (Pubitemid 41454662)
12. Watari F, Takashi N, Yokoyama A, Uo M, Akasaka T, Sato Y, Abe S, Totsuka Y, Tohji K. Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects. J R Soc Interface 2009; 6 Suppl 3:S371-388.
13. Kumazawa R, Watari F, Takashi N, Tanimura Y, Uo M, Totsuka Y. Effects of Ti ions and particles on cellular f unction and morphology of neutrophils. Biomaterials 2002;23:3757- 3764. (Pubitemid 34626576)
14. Tamura K, Takashi N, Kumazawa R, Watari F, Totsuka Y. Effects of particle size on cell function and morphology in titanium and nickel, Materials Transactions 2002;43:3052-3057.
15. Mantovani A, Sica A, Locati M. New vistas on macrophage differentiation and activation. Eur J Immunol 2007;37:14-16. (Pubitemid 46128780)
16. Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest 2008;118:3522-3530.
17. Komohara Y, Ohnishi K, Kuratsu J, Takeya M. Possible involvement of the M2 anti- inflammatory macrophage phenotype in growth of human gliomas. J Pathol 2008;216: 15-24.
18. Sato Y, Yokoyama A, Shibata K, Akimoto Y, Ogino S, Nodasaka Y, Kohgo T, Tamura K, Akasaka T, Uo M, Motomiya K, Jeyadevan B, Ishiguro M, Hatakeyama R, Watari F, Tohji K. Influence of length on cytotoxicity of multi- walled carbon nanotubes against human acute monocytic leukemia cell line THP-1 in vitro and subcutaneous tissue of rats in vivo, Molecular BioSystems 2005;1:176-182. (Pubitemid 43362245)
19. Kiura K, Sato Y, Yasuda M, Fugetsu B, Watari F, Tohji K, Shibata K. Activation of human monocytes and mouse splenocytes by single- walled carbon nanotubes, J Biomed Nanotechnology 2005;1:359-364.