In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases

Toxicology Letters

Volumn 206, Issue 1, 2011, Pages 24-28

  Ashani, Yacov ^a   Goldsmith, Moshe ^a   Leader, Haim ^a   Silman, Israel ^a   Sussman, Joel L ^a   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Cholinesterase; Cyclosarin; Detoxification; Nerve agent; Paraoxonase; Protection

Indexed keywords

ACETYLCHOLINESTERASE; ARYLDIALKYLPHOSPHATASE 1; CALCIUM ION; CHOLINESTERASE; CYCLOSARIN; ORGANOPHOSPHORUS COMPOUND;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETOXIFICATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; EX VIVO STUDY; HUMAN; HYDROLYSIS; IN VITRO STUDY; PRIORITY JOURNAL; PROPHYLAXIS;

ACETYLCHOLINESTERASE; ANTIDOTES; ARYLDIALKYLPHOSPHATASE; BIOCATALYSIS; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; ERYTHROCYTES; HUMANS; HYDROLYSIS; METABOLIC DETOXICATION, DRUG; NEUROTOXICITY SYNDROMES; ORGANOPHOSPHORUS COMPOUNDS; RECOMBINANT PROTEINS;

EID: 80051814341     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.07.017     Document Type: Article

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