Impact of derepressed AmpC β-lactamase ACT-9 on the clinical efficacy of ertapenem

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 9, 2011, Pages 4440-4442

  Lee, Yi Tzu ^a,b,c   Chen, Te Li ^a,c   Siu, Leung Kei ^d   Chen, Chien Pei ^c   Fung, Chang Phone ^a,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b Chutung Veterans Hospital   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAMASE AMPC; CEFAZOLIN; CEFEPIME; CEFMETAZOLE; CEFOTAXIME; CEFOTETAN; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; ERTAPENEM; GENTAMICIN; IMIPENEM; KANAMYCIN; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; DRUG EFFICACY; GENE FUNCTION; IN VIVO STUDY; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PANTOEA AGGLOMERANS; PRIORITY JOURNAL; TREATMENT RESPONSE;

AGED; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; BETA-LACTAMS; ENTEROBACTERIACEAE INFECTIONS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; PANTOEA;

EID: 80051808646     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00271-11     Document Type: Article

References (17)

1. Brasme, L., et al. 2007. Incidence of class A extended-spectrum β-lactamases in Champagne-Ardenne (France): A 1 year prospective study. J. Antimicrob. Chemother. 60:956-964. (Pubitemid 47617740)
2. Burkhardt, O., H. Derendorf, and T. Welte. 2007. Ertapenem: The new carbapenem 5 years after first FDA licensing for clinical practice. Expert Opin. Pharmacother. 8:237-256. (Pubitemid 46206625)
3. Chen, J H, et al. 2010. Contribution of outer membrane protein K36 to antimicrobial resistance and virulence in Klebsiella pneumoniae. J. Antimicrob. Chemother. 65:986-990.
4. Clinical and Laboratory Standards Institute. 2009. Performance standards for antimicrobial susceptibility testing; 19th informational supplement. CLSI document M100-S19. Clinical and Laboratory Standards Institute, Wayne, PA.
5. Clinical and Laboratory Standards Institute. 2010. Performance standards for antimicrobial susceptibility testing; update. CLSI document M100-S20, June 2010 update. Clinical and Laboratory Standards Institute, Wayne, PA.
6. Garcia-Fernandez, A., et al. 2010. An ertapenem-resistant extended-spectrum-β-lactamase-producing Klebsiella pneumoniae clone carries a novel OmpK36 porin variant. Antimicrob. Agents Chemother. 54:4178-4184.
7. Jacoby, G A, D M Mills, and N. Chow. 2004. Role of β-lactamases and porins in resistance to ertapenem and other β-lactams in Klebsiella pneumoniae. Antimicrob. Agents Chemother. 48:3203-3206. (Pubitemid 38989206)
8. Lee, Y T, et al. 2009. Differences in phenotypic and genotypic characteristics among imipenem-non-susceptible Acinetobacter isolates belonging to different genomic species in Taiwan. Int. J. Antimicrob. Agents 34:580-584.
9. Liepinsh, E., C. Genereux, D. Dehareng, B. Joris, and G. Otting. 2003. NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains. J. Mol. Biol. 327:833-842. (Pubitemid 36315922)
10. Mallea, M., J. Chevalier, A. Eyraud, and J M Pages. 2002. Inhibitors of antibiotic efflux pump in resistant Enterobacter aerogenes strains. Biochem. Biophys. Res. Commun. 293:1370-1373. (Pubitemid 34681027)
11. Padilla, E., et al. 2006. Effect of porins and plasmid-mediated AmpC β-lactamases on the efficacy of β-lactams in rat pneumonia caused by Klebsiella pneumoniae. Antimicrob. Agents Chemother. 50:2258-2260. (Pubitemid 43807560)
12. Pasteran, F., T. Mendez, L. Guerriero, M. Rapoport, and A. Corso. 2009. Sensitive screening tests for suspected class A carbapenemase production in species of Enterobacteriaceae. J. Clin. Microbiol. 47:1631-1639.
13. Pasteran, F., T. Mendez, M. Rapoport, L. Guerriero, and A. Corso. 2010. Controlling false-positive results obtained with the Hodge and Masuda assays for detection of class A carbapenemase in species of Enterobacteriaceae by incorporating boronic acid. J. Clin. Microbiol. 48:1323-1332.
14. Petrosino, J F, A R Pendleton, J H Weiner, and S M Rosenberg. 2002. Chromosomal system for studying AmpC-mediated β-lactam resistance mutation in Escherichia coli. Antimicrob. Agents Chemother. 46:1535-1539. (Pubitemid 34415339)
15. Siu, L K, P-L Lu, J-Y Chen, F M Lin, and S C Chang. 2003. High-level expression of AmpC β-lactamase due to insertion of nucleotides between -10 and -35 promoter sequences in Escherichia coli clinical isolates: Cases not responsive to extended-spectrum-cephalosporin treatment. Antimicrob. Agents Chemother. 47:2138-2144. (Pubitemid 36753563)
16. Woo, P C, E Y Cheung, K. Leung, and K. Yuen. 2001. Identification by 16S rRNA gene sequencing of an Enterobacteriaceae species with ambiguous biochemical profile from a renal transplant recipient. Diagn. Microbiol. Infect. Dis. 39:85-93. (Pubitemid 32206626)
17. Yagi, T., et al. 2005. Practical methods using boronic acid compounds for identification of class C β-lactamase-producing Klebsiella pneumoniae and Escherichia coli. J. Clin. Microbiol. 43:2551-2558. (Pubitemid 40827918)