Health care seeking among men with genital ulcer disease in South Africa: Correlates and relationship to human immunodeficiency virus-1 and herpes simplex virus type 2 detection and shedding

Sexually Transmitted Diseases

Volumn 38, Issue 9, 2011, Pages 865-870

  Leichliter, Jami S ^a   Lewis, David A ^b,c   Sternberg, Maya ^a   Habel, Melissa A ^a   Paz Bailey, Gabriela ^d,e  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSIDAD DEL VALLE DE GUATEMALA   (Guatemala)

^e Tephinet Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; GENITAL ULCER; HEALTH CARE; HEALTH CARE SEEKING BEHAVIOR; HELP SEEKING BEHAVIOR; HERPES SIMPLEX VIRUS 2; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; SEXUAL BEHAVIOR; SOUTH AFRICA; VIRUS DETECTION; VIRUS SHEDDING;

ACYCLOVIR; ADOLESCENT; ADULT; AGE FACTORS; ANTIVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; DELAYED DIAGNOSIS; GENITAL DISEASES, MALE; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HIV INFECTIONS; HIV-1; HUMANS; MALE; MIDDLE AGED; PATIENT ACCEPTANCE OF HEALTH CARE; SEX FACTORS; SEXUAL BEHAVIOR; SEXUALLY TRANSMITTED DISEASES; SOUTH AFRICA; TREATMENT OUTCOME; ULCER; VIRAL LOAD; VIRUS SHEDDING; YOUNG ADULT;

EID: 80051795992     PISSN: 01485717     EISSN: 15374521     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e31821d4ceb     Document Type: Article

References (26)

1. O'Farrell N, Morison L, Moodley P, et al. Genital ulcers and concomitant complaints in men attending a sexually transmitted infections clinic: Implications for sexually transmitted infections management. Sex Transm Dis 2008;35:545-549.
2. Paz-Bailey G, Rahman M, Chen C, et al. Changes in the etiology of sexually transmitted diseases in Botswana between 1993 and 2002: Implications for the clinical management of genital ulcer disease. Clin Infect Dis 2005;41:1304-1312. (Pubitemid 41532674)
3. Freeman EE, Weiss HA, Glynn JR, et al. Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-analysis of longitudinal studies. AIDS 2006;20:73-83. (Pubitemid 41818117)
4. Johnson LF, Lewis DA. The effect of genital tract infections on HIV-1 shedding in the genital tract: A systematic review and meta-analysis. Sex Transm Dis 2008;35:946-959.
5. Martinez V, Caumes E, Chosidow O. Treatment to prevent recurrent genital herpes. Curr Opin Infect Dis 2008;21:42-48.
6. Patel R, Rutland E. Has episodic treatment of recurrent genital herpes come of age? Int J STD AIDS 2007;18:437-439. (Pubitemid 351738954)
7. Paz-Bailey G, Sternberg M, Puren AJ, et al. Improvement in healing and reduction in HIV shedding with episodic acyclovir therapy as part of syndromic management among men: A randomized, controlled trial. J Infect Dis 2009;200:1039-1049.
8. Aral SO. Determinants of STD epidemics: Implications for phase appropriate intervention strategies. Sex Transm Infect 2002;78(suppl 1):i3-i13. (Pubitemid 34547994)
9. Wasserheit JN, Aral SO. The dynamic typology of sexually transmitted disease epidemics: Implications for prevention strategies. J Infect Dis 1996;174(suppl 2):S201-S213. (Pubitemid 26326158)
10. Mercer CH, Sutcliffe L, Johnson AM, et al. How much do delayed health care seeking, delayed care provision, and diversion from primary care contribute to the transmission of STIs? Sex Transm Infect 2007;83:400-405. (Pubitemid 47242491)
11. Voeten HACM, O'Hara HB, Kusimba J, et al. Gender differences in health care-seeking behavior for sexually transmitted diseases: A population-based study in Nairobi, Kenya. Sex Transm Dis 2004;31:265-272. (Pubitemid 38542654)
12. Meyer-Weitz A, Reddy P, Van den Borne HW, et al. Health care seeking behavior of patients with sexually transmitted diseases: Determinants of delay behavior. Patient Educ Couns 2000;41:263-274.
13. Wilson T, Strebel A, Simbayi L, et al. Health care-seeking behavior for sexually transmitted diseases in South Africa. J Psych Afr 2000;10:101-121.
14. Morris CN, Ferguson AG. Sexual and treatment-seeking behavior for sexually transmitted infection in long-distance transport workers of East Africa. Sex Transm Infect 2007;83:242-245. (Pubitemid 46999195)
15. Morgan D, Mahe C, Okongo JM, et al. Genital ulceration in rural Uganda: Sexual activity, treatment-seeking behavior, and the implications for HIV control. Sex Transm Dis 2001;28:431-436. (Pubitemid 32730287)
16. Lewis DA, Marumo E. Revision of the National guideline for first-line comprehensive management and control of sexually transmitted infections: What's new and why? S Afr Fam Pract 2010;52:20-24.
17. Corbell C, Stergachis A, Ndowa F, et al. Genital ulcer disease treatment policies and access to acylclovir in eight sub-Saharan African countries. Sex Transm Dis 2010;37:488-449.
18. Paz-Bailey G, Sternberg M, Puren AJ, et al. Determinants of HIV Type 1 shedding from genital ulcers among men in South Africa. Clin Infect Dis 2010;50:1060-1067.
19. Lewis D. Modern management of genital ulcer disease-Frappez fort et frappe vite. Sex Transm Dis 2010;37:494-496.
20. Leichliter JS, Paz-Bailey G, Friedman AL, et al. 'Clinics aren't meant for men': Sexual health care access and seeking behaviors among men in Gauteng province, South Africa. SAHARA (in press).
21. Lingappa JR, Baeten JM, Wald A, et al. Daily acyclovir for HIV-1 progression in people dually infected with HIV-1 and herpes simplex virus type 2: A randomized placebo-controlled trial. Lancet 2010;375:824-833.
22. White RG, Freeman EE, Orroth KK, et al. Population-level effect of HSV-2 therapy on the incidence of HIV in sub-Saharan Africa. Sex Transm Infect 2008;84:ii12-ii18.
23. Bogaerts J, Kestens L, van Dyck E, et al. Genital ulcers in a primary health clinic in Rwanda: Impact of HIV infection on diagnosis and ulcer healing (1986-1992). Int J STD AIDS 1998;9:706-710. (Pubitemid 28539851)
24. Smith JS, Robinson NJ. Age-specific prevalence of infection with herpes simplex virus types 2 and 1: A global review. J Infect Dis 2002;186(suppl 1):S3-S28. (Pubitemid 35178845)
25. Ahmed HJ, Mbwana J, Gunnarsson E, et al. Etiology of genital ulcer disease and association with human immunodeficiency virus infection in two Tanzanian cities. Sex Transm Dis 2003;30:114-119. (Pubitemid 36184357)
26. LeGoff J, Weiss HA, Gresenguet G, et al. Cervicovaginal HIV-1 and herpes simplex virus type 2 shedding during genital ulcer disease episodes. AIDS 2007;21:1569-1578. (Pubitemid 47075478)