Genital ulcers and concomitant complaints in men attending a aexually transmitted infections clinic: Implications for sexually transmitted infections management

Sexually Transmitted Diseases

Volumn 35, Issue 6, 2008, Pages 545-549

  O'Farrell, Nigel ^a,b   Morison, Linda ^b   Moodley, Prashini ^c   Pillay, Keshree ^c   Vanmali, Trusha ^c   Quigley, Maria ^b   Sturm, A Wim ^c  

^a EALING HOSPITAL   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; VIRUS ANTIBODY;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIUM DETECTION; CHLAMYDIA TRACHOMATIS; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONTROLLED STUDY; DYSURIA; GENITAL ULCER; GONORRHEA; GRANULOMA INGUINALE; HAEMOPHILUS DUCREYI; HEALTH CENTER; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 2; HIGH RISK PATIENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOASSAY; LYMPHOGRANULOMA VENEREUM; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; NEISSERIA GONORRHOEAE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PREDICTOR VARIABLE; PREVALENCE; SENSITIVITY AND SPECIFICITY; SYPHILIS; TREPONEMA PALLIDUM; TRICHOMONAS VAGINALIS; ANAMNESIS; BLOOD; CLASSIFICATION; GENETICS; GENITAL HERPES; IMMUNOLOGY; ISOLATION AND PURIFICATION; METHODOLOGY; MICROBIOLOGY; MIDDLE AGED; OUTPATIENT DEPARTMENT; PARASITOLOGY; PATHOPHYSIOLOGY; SEXUALLY TRANSMITTED DISEASE; SOUTH AFRICA; URETHRA; VIROLOGY;

ADOLESCENT; ADULT; AGED; AMBULATORY CARE FACILITIES; ANTIBODIES, VIRAL; DYSURIA; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HUMANS; MALE; MEDICAL HISTORY TAKING; MIDDLE AGED; POLYMERASE CHAIN REACTION; SEXUALLY TRANSMITTED DISEASES; SOUTH AFRICA; URETHRA;

EID: 48049113989     PISSN: 01485717     EISSN: None     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e31816a4f2e     Document Type: Article

References (23)

1. Dickerson MC, Johnstone J, Delea TE, et al. The causal role for genital ulcer disease as a risk factor for transmission of human immunodeficiency virus. Sex Transm Dis 1996; 23:429-440.
2. O'Farrell N, Windsor I, Becker P. Risk factors for HIV-1 in heterosexual attenders at a sexually transmitted diseases clinic in Durban. S Afr Med J 1991; 80:17-20.
3. Bogaerts J, Vuylsteke B, Martinez Tello W, et al. Simple algorithms for the management of genital ulcers: Evaluation in a primary health care centre in Kigali, Rwanda. Bull WHO 1995; 73:761-767.
4. Ndinya- Achola JO, Kihara AN, Fisher LD, et al. Presumptive specific clinical diagnosis of genital ulcer disease in a primary health care setting in Nairobi. Int J STD AIDS 1996; 7:201-205.
5. O'Farrell N. Increasing prevalence of genital herpes in developing countries: Implications for heterosexual HIV transmission and STI control programmes. Sex Transm Infect 1999; 75:377-384.
6. Chen CY, Ballard RC, Beck-Sague CM, et al. Human immunodeficiency virus infection and genital ulcer disease in South Africa: The herpetic connection. Sex Transm Dis 2000; 27:21-29.
7. Moodley P, Sturm PJ, Vanmali T, et al. Association between HIV-1 infection, the etiology of genital ulcer disease, and response to syndromic management. Sex Transm Dis 2003; 30:241-245.
8. Lai W, Chen CY, Morse SA, et al. Increasing relative prevalence of HSV-2 infection among men with genital ulcers from a mining community in South Africa. Sex Trans Infect 2003; 79:202-207.
9. Paz- Bailey G, Rahman M, Chen CY, et al. Changes in the aetiology of sexually transmitted diseases in Botswana between 1993 and 2002: Implications for the management of genital ulcer disease. Clin Infect Dis 2005; 41:1304-1312.
10. WHO. Guidelines for the Management of Sexually Transmitted Infections. Geneva, Switzerland: WHO, 2003.
11. Wald A, Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 2 seropositive persons: A meta analysis. J Infect Dis 2002; 185:45-52.
12. O'Farrell N, Morison L, Moodley P, et al. Association between HIV and subpreputial penile wetness in uncircumcised men in South Africa. JAIDS 2006; 43:69-77.
13. Sturm PD, Moodley P, Govender K, et al. Molecular diagnosis of lymphogranuloma venereum in patients with genital ulcer disease. J Clin Microbiol 2005; 43:2973-2975.
14. Watson MW, Lambden PR, Clarke IN. Genetic diversity and identification of human infection by amplification of the chlamydial 60-kilodalton cysteine-rich outer membrane protein gene. J Clin Microbiol 1991; 29:1188-1193.
15. Sturm PD, Moodley P, Khan M, et al. Aetiology of male urethritis in patients recruited from a population with a high HIV prevalence. Int J Antimicrobial Agents 2004; 24(suppl 1):S8-S14.
16. Lauritsen JM, Bruus M. EpiData (version 3). A Comprehensive Tool for Validated Entry and Documentation of Data. Odense, Denmark: The EpiData Association, 2003.
17. Ballard RC, Fehler HG, Htun Y, et al. Coexistence of urethritis with genital ulcer disease in South Africa: Influence on provision of syndromic management. Sex Transm Infect 2002; 78:274-277.
18. Price MA, Zimba D, Hoffman IR, et al. Addition of treatment for trichomoniasis to syndromic management of urethritis in Malawi. Sex Transm Dis 2003; 30:516-522.
19. Hoyo C, Hoffman I, Moser BK, et al. Improving the accuracy of syndromic diagnosis of genital ulcer disease in Malawi. Sex Transm Dis 2005; 32:231-237.
20. Fife KH, Almekinder J, Ofner S. A comparison of one year of episodic or suppressive treatment of recurrent genital herpes with valacyclovir. Sex Transm Dis 2007; 34:297-301.
21. O'Farrell N, Moodley P, Sturm AW. Genital herpes in Africa: time to rethink treatment. Lancet 2007; 370:2164-2166.
22. Scoular A, Gillespie G, Carman WF. Polymerase chain reaction for diagnosis of genital herpes in a genitourinary medicine clinic. Sex Transm Infect 2002; 78:21-25.
23. Trollope-Kumar K, Guyatt G. Syndromic approach for treatment of STIs: Time for a change. Lancet 2006; 367:1380-1381.