Sebaceous gland loss and inflammation in scarring alopecia: A potential role in pathogenesis

Journal of the American Academy of Dermatology

Volumn 65, Issue 3, 2011, Pages 597-603

  Al Zaid, Tariq ^a   Vanderweil, Stefan ^b   Zembowicz, Artur ^a   Lyle, Stephen ^b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

pathogenesis; pathology; scarring alopecia; sebaceous gland

Indexed keywords

ALOPECIA; HAIR DISEASE; HAIR FOLLICLE; HAIR FOLLICLE INFLAMMATION; HUMAN; INFLAMMATION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SCARRING ALOPECIA; SCORING SYSTEM; SEBACEOUS GLAND DISEASE; SEBACEOUS GLAND DUCT INFLAMMATION; SEBACEOUS GLAND INFLAMMATION; SEBACEOUS GLAND LOSS;

EID: 80051787322     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2010.09.774     Document Type: Article

References (16)

1. K.S. Stenn, J.P. Sundberg, and L.C. Sperling Hair follicle biology, the sebaceous gland, and scarring alopecias Arch Dermatol 135 1999 973 974 (Pubitemid 29382437)
2. N. Somani, and W.F. Bergfeld Cicatricial alopecia: classification and histopathology Dermatol Ther 21 2008 221 237 (Pubitemid 352009067)
3. P. Mirmirani, A. Willey, J.T. Headington, K. Stenn, T.H. McCalmont, and V.H. Price Primary cicatricial alopecia: histopathologic findings do not distinguish clinical variants J Am Acad Dermatol 52 2005 637 643 (Pubitemid 40585435)
4. M.M. Downie, and T. Kealey Lipogenesis in the human sebaceous gland: glycogen and glycerophosphate are substrates for the synthesis of sebum lipids J Invest Dermatol 111 1998 199 205 (Pubitemid 28354703)
5. K.S. Stenn Insights from the asebia mouse: a molecular sebaceous gland defect leading to cicatricial alopecia J Cutan Pathol 28 2001 445 447 (Pubitemid 32881880)
6. K.J. McElwee Etiology of cicatricial alopecias: a basic science point of view Dermatol Ther 21 2008 212 220 (Pubitemid 352009066)
7. K.J. McElwee, M. Yu, S.W. Park, E.K. Ross, A. Finner, and J. Shapiro What can we learn from animal models of alopecia areata? Dermatology 211 2005 47 53 (Pubitemid 40911564)
8. P. Matzinger The danger model: a renewed sense of self Science 296 2002 301 305 (Pubitemid 34303674)
9. J.T. Headington Cicatricial alopecia Dermatol Clin 14 1996 773 782 (Pubitemid 26322545)
10. L.C. Sperling, and S.E. Cowper The histopathology of primary cicatricial alopecia Semin Cutan Med Surg 25 2006 41 50
11. A.H. Gates, and M. Karasek Hereditary absence of sebaceous glands in the mouse Science 148 1965 1471 1473
12. J.P. Sundberg, D. Boggess, B.A. Sundberg, K. Eilersten, S. Parimoo, and M. Filippi Asebia-2J (Scd1(ab2J)): a new allele and a model for scarring alopecia Am J Pathol 156 2000 2067 2075 (Pubitemid 30641774)
13. H. Oshima, A. Rochat, C. Kedzia, K. Kobayashi, and Y. Barrandon Morphogenesis and renewal of hair follicles from adult multipotent stem cells Cell 104 2001 233 245 (Pubitemid 32174839)
14. R.J. Morris, Y. Liu, L. Marles, Z. Yang, C. Trempus, and S. Li Capturing and profiling adult hair follicle stem cells Nat Biotechnol 22 2004 411 417 (Pubitemid 38451371)
15. K.B. Jensen, C.A. Collins, E. Nascimento, D.W. Tan, M. Frye, and S. Itami Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis Cell Stem Cell 4 2009 427 439
16. C. Roh, M. Roche, Z. Guo, C. Photopoulos, Q. Tao, and S. Lyle Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In Vitro Cell Dev Biol Anim 44 2008 236 244