메뉴 건너뛰기




Volumn 416, Issue 1, 2011, Pages 129-135

The influence of drug loading on formulation structure and aerosol performance in carrier based dry powder inhalers

Author keywords

Active sites; Dry powder inhaler; Inhalation medicine; Powder blending; Spherical carrier

Indexed keywords

DRUG CARRIER; POLYSTYRENE; SALBUTAMOL SULFATE;

EID: 80051784971     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.06.020     Document Type: Article
Times cited : (44)

References (20)
  • 1
    • 52449114489 scopus 로고    scopus 로고
    • Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios
    • H. Adi, I. Larson, H. Chiou, P. Young, D. Traini, and P. Stewart Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios J. Pharm. Sci. 97 2008 3140 3152
    • (2008) J. Pharm. Sci. , vol.97 , pp. 3140-3152
    • Adi, H.1    Larson, I.2    Chiou, H.3    Young, P.4    Traini, D.5    Stewart, P.6
  • 3
    • 0042836858 scopus 로고    scopus 로고
    • The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time
    • DOI 10.1016/S0939-6411(03)00109-7
    • B.H.J. Dickhoff, A.H. de Boer, D. Lambregts, and H.W. Frijlink The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time Eur. J. Pharm. Biopharm. 56 2003 291 302 (Pubitemid 37072114)
    • (2003) European Journal of Pharmaceutics and Biopharmaceutics , vol.56 , Issue.2 , pp. 291-302
    • Dickhoff, B.H.J.1    De Boer, A.H.2    Lambregts, D.3    Frijlink, H.W.4
  • 4
    • 9644284349 scopus 로고    scopus 로고
    • The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation
    • DOI 10.1016/j.ejpb.2004.07.005, PII S0939641104001997
    • B.H.J. Dickhoff, A.H. de Boer, D. Lambregts, and H.W. Frijlink The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation Eur. J. Pharm. Biopharm. 59 2005 197 205 (Pubitemid 39573453)
    • (2005) European Journal of Pharmaceutics and Biopharmaceutics , vol.59 , Issue.1 , pp. 197-205
    • Dickhoff, B.H.J.1    De Boer, A.H.2    Lambregts, D.3    Frijlink, H.W.4
  • 5
    • 78349311366 scopus 로고    scopus 로고
    • Influence of size and surface roughness of large lactose carrier particles in dry powder inhaler formulations
    • M.J. Donovan, and H.D. Smyth Influence of size and surface roughness of large lactose carrier particles in dry powder inhaler formulations Int. J. Pharm. 402 2010 1 9
    • (2010) Int. J. Pharm. , vol.402 , pp. 1-9
    • Donovan, M.J.1    Smyth, H.D.2
  • 6
    • 33750847407 scopus 로고    scopus 로고
    • Continued investigation into the influence of loaded dose on the performance of dry powder inhalers: Surface smoothing effects
    • DOI 10.1080/03639040600712920, PII HR8143121TU88357
    • D. El-Sabawi, S. Edge, R. Price, and P. Young Continued investigation into the influence of loaded dose on the performance of dry powder inhalers: surface smoothing effects Drug Dev. Ind. Pharm. 32 2006 1135 1138 (Pubitemid 44721727)
    • (2006) Drug Development and Industrial Pharmacy , vol.32 , Issue.10 , pp. 1135-1138
    • El-Sabawi, D.1    Edge, S.2    Price, R.3    Young, P.M.4
  • 7
    • 69549118327 scopus 로고    scopus 로고
    • Understanding the effect of lactose particle size on the properties of DPI formulations using experimental design
    • E. Guenette, A. Barrett, D. Kraus, R. Brody, L. Harding, and G. Magee Understanding the effect of lactose particle size on the properties of DPI formulations using experimental design Int. J. Pharm. 380 2009 80 88
    • (2009) Int. J. Pharm. , vol.380 , pp. 80-88
    • Guenette, E.1    Barrett, A.2    Kraus, D.3    Brody, R.4    Harding, L.5    Magee, G.6
  • 8
    • 0346784815 scopus 로고
    • Ordered mixing - New concept in powder mixing practice
    • J.A. Hersey Ordered mixing - new concept in powder mixing practice Powder Technol. 11 1975 41 44
    • (1975) Powder Technol. , vol.11 , pp. 41-44
    • Hersey, J.A.1
  • 9
    • 1842429885 scopus 로고    scopus 로고
    • Effect of Carrier Size on the Dispersion of Salmeterol Xinafoate from Interactive Mixtures
    • DOI 10.1002/jps.10583
    • N. Islam, P. Stewart, I. Larson, and P. Hartley Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures J. Pharm. Sci. 93 2004 1030 1038 (Pubitemid 38420412)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.4 , pp. 1030-1038
    • Islam, N.1    Stewart, P.2    Larson, I.3    Hartley, P.4
  • 10
    • 1542615802 scopus 로고    scopus 로고
    • Lactose surface modification by decantation: Are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose-interactive mixtures?
    • DOI 10.1023/B:PHAM.0000019304.91412.18
    • N. Islam, P. Stewart, I. Larson, and P. Hartley Lactose surface modification by decantation: are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose-interactive mixtures? Pharm. Res. 21 2004 492 499 (Pubitemid 38338985)
    • (2004) Pharmaceutical Research , vol.21 , Issue.3 , pp. 492-499
    • Islam, N.1    Stewart, P.2    Larson, I.3    Hartley, P.4
  • 11
    • 33746916510 scopus 로고    scopus 로고
    • The influence of fine excipient particles on the performance of carrier-based dry powder inhalation formulations
    • DOI 10.1007/s11095-006-9012-7
    • M.D. Jones, and R. Price The influence of fine excipient particles on the performance of carrier-based dry powder inhalation formulations Pharm. Res. 23 2006 1665 1674 (Pubitemid 44200528)
    • (2006) Pharmaceutical Research , vol.23 , Issue.8 , pp. 1665-1674
    • Jones, M.D.1    Price, R.2
  • 12
    • 0032531782 scopus 로고    scopus 로고
    • Effect of surface morphology of carrier lactose on dry powder inhalation property of pranlukast hydrate
    • DOI 10.1016/S0378-5173(98)00202-6, PII S0378517398002026
    • Y. Kawashima, T. Serigano, T. Hino, H. Yamamoto, and H. Takeuchi Effect of surface morphology of carrier lactose on dry powder inhalation property of pranlukast hydrate Int. J. Pharm. 172 1998 179 188 (Pubitemid 28430255)
    • (1998) International Journal of Pharmaceutics , vol.172 , Issue.1-2 , pp. 179-188
    • Kawashima, Y.1    Serigano, T.2    Hino, T.3    Yamamoto, H.4    Takeuchi, H.5
  • 13
    • 0036804484 scopus 로고    scopus 로고
    • Particle interactions involved in aerosol dispersion of ternary interactive mixtures
    • DOI 10.1023/A:1020464801786
    • M.D. Louey, and P.J. Stewart Particle interactions involved in aerosol dispersion of ternary interactive mixtures Pharm. Res. 19 2002 1524 1531 (Pubitemid 35266558)
    • (2002) Pharmaceutical Research , vol.19 , Issue.10 , pp. 1524-1531
    • Louey, M.D.1    Stewart, P.J.2
  • 14
    • 79957975554 scopus 로고    scopus 로고
    • Does carrier size matter? A fundamental study of drug aerosolisation from carrier based dry powder inhalation systems
    • J. Ooi, D. Traini, S. Hoe, W. Wong, and P.M. Young Does carrier size matter? A fundamental study of drug aerosolisation from carrier based dry powder inhalation systems Int. J. Pharm 413 2011 1 9
    • (2011) Int. J. Pharm , vol.413 , pp. 1-9
    • Ooi, J.1    Traini, D.2    Hoe, S.3    Wong, W.4    Young, P.M.5
  • 15
    • 0037346651 scopus 로고    scopus 로고
    • The inhalers of the future? A review of dry powder devices on the market today
    • DOI 10.1016/S1094-5539(02)00147-5
    • I.J. Smith, and M. Parry-Billings The inhalers of the future? a review of dry powder devices on the market today Pulm. Pharmacol. Therap. 16 2003 79 95 (Pubitemid 36372063)
    • (2003) Pulmonary Pharmacology and Therapeutics , vol.16 , Issue.2 , pp. 79-95
    • Smith, I.J.1    Parry-Billings, M.2
  • 16
    • 52149086340 scopus 로고    scopus 로고
    • The influence of lactose pseudopolymorphic form on salbutamol sulfate-lactose interactions in DPI formulations
    • D. Traini, P.M. Young, F. Thielmann, and M. Acharya The influence of lactose pseudopolymorphic form on salbutamol sulfate-lactose interactions in DPI formulations Drug Dev. Ind. Pharm. 34 2008 992 1001
    • (2008) Drug Dev. Ind. Pharm. , vol.34 , pp. 992-1001
    • Traini, D.1    Young, P.M.2    Thielmann, F.3    Acharya, M.4
  • 19
    • 61449219797 scopus 로고    scopus 로고
    • Lactose composite carriers for respiratory delivery
    • P.M. Young, P. Kwok, H. Adi, H.K. Chan, and D. Traini Lactose composite carriers for respiratory delivery Pharm. Res. 26 2009 802 810
    • (2009) Pharm. Res. , vol.26 , pp. 802-810
    • Young, P.M.1    Kwok, P.2    Adi, H.3    Chan, H.K.4    Traini, D.5
  • 20
    • 34249281670 scopus 로고    scopus 로고
    • The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance
    • DOI 10.1002/jps.20933
    • P.M. Young, D. Traini, H.K. Chan, H. Chiou, S. Edge, and T. Tee The influence of mechanical processing dry powder inhaler carriers on drug aerosolisation performance J. Pharm. Sci 96 5 2007 1331 1341 (Pubitemid 46804584)
    • (2007) Journal of Pharmaceutical Sciences , vol.96 , Issue.5 , pp. 1331-1341
    • Young, P.M.1    Chan, H.-K.2    Chiou, H.3    Edge, S.4    Tee, T.H.S.5    Traini, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.