Two-year results from a Swedish study on conventional versus accelerated radiotherapy in head and neck squamous cell carcinoma - The ARTSCAN study

Radiotherapy and Oncology

Volumn 100, Issue 1, 2011, Pages 41-48

  Zackrisson, Björn ^a   Nilsson, Per ^a,b   Kjellén, Elisabeth ^b   Johansson, Karl Axel ^c   Modig, Hans ^a   Brun, Eva ^b   Nyman, Jan ^c   Friesland, Signe ^d   Reizenstein, Johan ^e   Sjödin, Helena ^d   Ekberg, Lars ^b   Lödén, Britta ^f   Mercke, Claes ^d   Fernberg, Jan Olof ^d   Franzén, Lars ^a   Ask, Anders ^b   Persson, Essie ^e   Wickart Johansson, Gun ^d   Lewin, Freddi ^d   Wittgren, Lena ^b   Björ, Ove ^a   Björk Eriksson, Thomas ^c   more..

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

^f CENTRAL HOSPITAL   (Sweden)

Author keywords

Accelerated fractionation; Head and neck cancer; Radiotherapy; Randomised trial

Indexed keywords

ACCELERATED RADIATION DOSE FRACTIONATION; ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CLINICAL PROTOCOL; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; CONVENTIONAL RADIATION DOSE FRACTIONATION; DYSPHAGIA; EPITHELITIS; FEMALE; HEAD AND NECK CARCINOMA; HEALTH CARE QUALITY; HUMAN; HYPOPHARYNX CARCINOMA; INTENSITY MODULATED RADIATION THERAPY; INTERMETHOD COMPARISON; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MOUTH CARCINOMA; MUCOSA INFLAMMATION; OROPHARYNX CARCINOMA; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RANDOMIZED CONTROLLED TRIAL; SQUAMOUS CELL CARCINOMA; SURVIVAL TIME; SWEDEN; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; DOSE FRACTIONATION; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MORBIDITY; SWEDEN;

EID: 80051784833     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2010.12.010     Document Type: Article

References (35)

1. W. Garavello, A. Ciardo, R. Spreafico, and R.M. Gaini Risk factors for distant metastases in head and neck squamous cell carcinoma Arch Otolaryngol Head Neck Surg 132 2006 762 766 (Pubitemid 44086440)
2. H.R. Withers, J.M. Taylor, and B. Maciejewski The hazard of accelerated tumor clonogen repopulation during radiotherapy Acta Oncol 27 1988 131 146
3. J. Overgaard, M. Hjelm-Hansen, L.V. Johansen, and A.P. Andersen Comparison of conventional and split-course radiotherapy as primary treatment in carcinoma of the larynx Acta Oncol 27 1988 47 52
4. J.F. Fowler, and M.J. Lindstrom Loss of local control with prolongation in radiotherapy Int J Radiat Oncol Biol Phys 23 1992 457 467
5. B. Zackrisson, H. Gustafsson, R. Stenling, P. Flygare, and G.D. Wilson Predictive value of potential doubling time in head and neck cancer patients treated by conventional radiotherapy Int J Radiat Oncol Biol Phys 38 1997 677 683 (Pubitemid 27310534)
6. B. Zackrisson, P. Flygare, H. Gustafsson, B. Sjöström, and G.D. Wilson Cell kinetic changes in human squamous cell carcinomas during radiotherapy studied using the in vivo administration of two halogenated pyrimidines Eur J Cancer 38 2002 1100 1106 (Pubitemid 34468015)
7. J. Fowler The linear-quadratic formula and progress in fractionated radiotherapy Br J Radiol 62 1989 679 694 (Pubitemid 19194494)
8. J.F. Fowler How worthwhile are short schedules in radiotherapy? A series of exploratory calculations Radiother Oncol 18 1990 165 168
9. S. Dische, M. Saunders, A. Barrett, A. Harvey, D. Gibson, and M. Parmar A randomised multicenter trial of CHART versus conventional radiotherapy in head and neck cancer Radiother Oncol 44 1997 123 136 (Pubitemid 27345199)
10. M. Saunders, A.M. Rojas, M.K. Parmar, S. Dische CHART Trial Collaborators Mature results of a randomized trial of accelerated hyperfractionated versus conventional radiotherapy in head-and-neck cancer Int J Radiat Oncol Biol Phys 77 2010 3 8
11. S.M. Jackson, L.M. Weir, J.H. Hay, V.H. Tsang, and J.S. Durham A randomized trial of accelerated versus conventional radiotherapy in head and neck cancer Radiother Oncol 43 1997 39 46 (Pubitemid 27191977)
12. J.C. Horiot, P. Bontemps, and W. Van Den Bogaert Accelerated fractionation compared to conventional fractionation improves locoregional control in the radiotherapy of advanced head and neck cancer: results of the EORTC 22851 randomized trial Radiother Oncol 44 1997 39 46
13. International Commission on Radiation Units and Measurements, I. Prescribing, recording and reporting photon beam therapy report 50. Bethesda MD; 1993.
14. International Commission on Radiation Units and Measurements, I, (Supplement to ICRU Report 50). Prescribing, recording, and reporting photon beam therapy. Bethesda MD; 1999.
15. K.A. Johansson, P. Nilsson, and B. Zackrisson The quality assurance process for the ARTSCAN head and neck study - a practical interactive approach for QA in 3DCRT and IMRT Radiother Oncol 87 2008 290 299
16. S.J. Pocock, and R. Simon Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial Biometrics 31 1975 102 115
17. EORTC Late Effects Working Group LENT SOMA tables Radiother Oncol 35 1995 17 60
18. K.K. Fu, T.F. Pajak, and A. Trotti A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003 Int J Radiat Oncol Biol Phys 48 2000 7 16 (Pubitemid 30488207)
19. K. Skladowski, B. Maciejewski, M. Golen, B. Pilecki, W. Przeorek, and R. Tarnawski Randomized clinical trial on 7-days-continuous accelerated irradiation (CAIR) of head and neck cancer - report on 3-year tumor control and normal tissue toxicity Radiother Oncol 55 2000 101 110 (Pubitemid 30229984)
20. M.G. Poulsen, J.W. Denham, and L.J. Peters A randomised trial of accelerated and conventional radiotherapy for stage III and IV squamous carcinoma of the head and neck: a trans-tasman radiation oncology group study Radiother Oncol 60 2001 113 122 (Pubitemid 32601964)
21. A. Hliniak, B. Gwiazdowska, and Z. Szutkowski A multicenter randomized/controlled trial of a conventional versus modestly accelerated radiotherapy in the laryngeal cancer: influence of a 1 week shortening overall time Radiother Oncol 62 2002 1 10 (Pubitemid 34121944)
22. J. Overgaard, H.S. Hansen, and L. Specht Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomised controlled trial Lancet 362 2003 933 940 (Pubitemid 37159288)
23. P. Olmi, S. Crispino, and C. Fallai Locoregionally advanced carcinoma of the oropharynx: conventional radiotherapy versus accelerated hyperfractionated radiotherapy versus concomitant radiotherapy and chemotherapy - a multicenter randomized trial Int J Radiat Oncol Biol Phys 55 2003 78 92 (Pubitemid 36020346)
24. J. Bourhis, M. Lapeyre, and J. Tortochaux Phase III randomized trial of very accelerated radiation therapy compared with conventional radiation therapy in squamous cell head and neck cancer: a GORTEC trial J Clin Oncol 24 2006 2873 2878 (Pubitemid 46630588)
25. J. Overgaard, B.K. Mohanti, and N. Begum Five versus six fractions of radiotherapy per week for squamous cell carcinoma of the head and neck (IAEA-ACC study): a randomised, multicentre trial Lancet Oncol 11 2010 553 560
26. J. Bourhis, J. Overgaard, and H. Audry Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis Lancet 368 2006 843 854 (Pubitemid 44292807)
27. D. Rishin, L. Peters, and B. O'Sullivan Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): a phase III trial of the trans-tasman radiation oncology group J Clin Oncol 28 2010 2989 2995
28. D. Lindquist, M. Romanitan, and L. Hammarstedt Human papillomavirus is a favourable prognostic factor in tonsillar cancer and its oncogenic role is supported by the expression of E6 and E7 Mol Oncol 1 2007 350 355 (Pubitemid 350186274)
29. A.C. Nichols, W.C. Faquin, and W.H. Westra HPV-16 infection predicts treatment outcome in oropharyngeal squamous cell carcinoma Otolaryngol Head Neck Surg 140 2009 228 234
30. A. Näsman, P. Attner, and L. Hammarstedt Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer 125 2009 362 366
31. P. Lassen The role of human papillomavirus in head and neck cancer and the impact on radiotherapy outcome Radiother Oncol 95 2010 371 380
32. J.F. Fowler Is there an optimum overall time for head and neck radiotherapy? A review, with new modelling Clin Oncol 19 2007 8 22 (Pubitemid 46044065)
33. J. Fowler 1 Practical time-dose evaluation or how to stop worrying and learn how to love linear quadratics S.H. Levitt, J.A. Purdy, C.A. Perez, S. Vijakumar, Technical basis of radiation therapy. Practical clinical applications 2008 Springer Berlin, Heidelberg 3 31
34. J. Bernier, C. Domenge, and M. Ozsahin Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer N Engl J Med 350 2004 1945 1952 (Pubitemid 38580197)
35. J.S. Cooper, T.F. Pajak, and A.A. Forastiere Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck N Engl J Med 350 2004 1937 1944