In vivo cardioprotection by pitavastatin from ischemic-reperfusion injury through suppression of IKK/NF-κB and upregulation of pAkt-e-NOS

Journal of Cardiovascular Pharmacology

Volumn 58, Issue 2, 2011, Pages 199-206

  Malik, Salma ^a   Sharma, Ashok Kumar ^a   Bharti, Saurabh ^a   Nepal, Saroj ^a   Bhatia, Jagriti ^a   Nag, Tapas Chandra ^a   Narang, Rajiv ^a   Arya, Dharamvir Singh ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

antioxidant; apoptosis; ischemia reperfusion injury; pAkt e NOS; pitavastatin

Indexed keywords

3 NITROTYROSINE; CASPASE 3; CREATINE KINASE ISOENZYME; CREATINE KINASE MB; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; PITAVASTATIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HEART; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART PROTECTION; HEART RATE; HISTOPATHOLOGY; IN VIVO STUDY; INFLAMMATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SHAM PROCEDURE; UPREGULATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; HEMODYNAMICS; I-KAPPA B KINASE; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE III; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLINES; RATS; RATS, WISTAR; UP-REGULATION;

EID: 80051783999     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31822002a6     Document Type: Article

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