The postnatal accumulation of junctional e-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs

Journal of Neuroscience

Volumn 31, Issue 33, 2011, Pages 11855-11866

  Collado, Maria Sol ^a   Thiede, Benjamin R ^a   Baker, Wendy ^a   Askew, Charles ^a   Igbani, Lisa M ^a   Corwin, Jeffrey T ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN VI; MYOSIN VIIA; NERVE CELL ADHESION MOLECULE; UVOMORULIN;

ADULT; AGE; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BODY EQUILIBRIUM; CONTROLLED STUDY; CORTI ORGAN; FEMALE; GENE; GENE EXPRESSION; HAIR CELL; HES GENE; HEY GENE; HUMAN; HUMAN TISSUE; INTERNALIZATION; MALE; MOUSE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UTRICLE;

ADHERENS JUNCTIONS; ADULT; ANIMALS; ANIMALS, NEWBORN; CADHERINS; CELL COUNT; CELLS, CULTURED; FEMALE; HAIR CELLS, AUDITORY; HAIR CELLS, VESTIBULAR; HUMANS; MALE; MICE; MICE, TRANSGENIC; POSTURAL BALANCE; SACCULE AND UTRICLE;

EID: 80051767228     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2525-11.2011     Document Type: Article

References (45)

1. Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY (1999) Math1: an essential gene for the generation of inner ear hair cells. Science 284:1837-1841.
2. Brooker R, Hozumi K, Lewis J (2006) Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development 133:1277-1286.
3. Burns J, Christophel JJ, Collado MS, Magnus C, Carfrae M, Corwin JT (2008) Reinforcement of cell junctions correlates with the absence of hair cell regeneration in mammals and its occurrence in birds. J Comp Neurol 511:396-414.
4. Cavey M, Rauzi M, Lenne PF, Lecuit T (2008) A two-tiered mechanism for stabilization and immobilization of E-cadherin. Nature 453:751-756.
5. Chausovsky A, Bershadsky AD, Borisy GG (2000) Cadherin-mediated regulation of microtubule dynamics. Nat Cell Biol 2:797-804.
6. Davies D, Magnus C, Corwin JT (2007) Developmental changes in cellextracellular matrix interactions limit proliferation in the mammalian inner ear. Eur J Neurosci 25:985-998.
7. Davies S, Forge A (1987) Preparation of the mammalian organ of Corti for scanning electron microscopy. J Microsc 147:89-101.
8. Denman-Johnson K, Forge A (1999) Establishment of hair bundle polarity and orientation in the developing vestibular system of the mouse. J Neurocytol 28:821-835.
9. Doetzlhofer A, Basch ML, Ohyama T, Gessler M, Groves AK, Segil N (2009) Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell 16:58-69.
10. Favre D, Bagger-Sjöbäck D, Mbiene JP, Sans A (1986) Freeze-fracture study of the vestibular hair cell surface during development. Anat Embryol (Berl) 175:69-76.
11. Forge A, Souter M, Denman-Johnson K (1997) Structural development of sensory cells in the ear. Semin Cell Dev Biol 8:225-237.
12. Fortini ME (2002) Gamma-secretase-mediated proteolysis in cell-surfacereceptor signalling. Nat Rev Mol Cell Biol 3:673-684.
13. Gu R, Montcouquiol M, Marchionni M, Corwin JT (2007) Proliferative responses to growth factors decline rapidly during postnatal maturation of mammalian hair cell epithelia. Eur J Neurosci 25:1363-1372.
14. Gubbels SP, Woessner DW, Mitchell JC, Ricci AJ, Brigande JV (2008) Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 455:537-541.
15. Gumbiner BM (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84:345-357.
16. Hackett L, Davies D, Helyer R, Kennedy H, Kros C, Lawlor P, Rivolta MN, Holley M (2002) E-cadherin and the differentiation of mammalian vestibular hair cells. Exp Cell Res 278:19-30.
17. Hajra KM, Chen DY, Fearon ER (2002) The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 62:1613-1618.
18. Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O (2008) Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol 316:87-99.
19. Hines MD, Jin HC, Wheelock MJ, Jensen PJ (1999) Inhibition of cadherin function differentially affects markers of terminal differentiation in cultured human keratinocytes. J Cell Sci 112:4569-4579.
20. Hori R, Nakagawa T, Sakamoto T, Matsuoka Y, Takebayashi S, Ito J (2007) Pharmacological inhibition of Notch signaling in the mature guinea pig cochlea. Neuroreport 18:1911-1914.
21. Kelley MW (2006) Regulation of cell fate in the sensory epithelia of the inner ear. Nat Rev Neurosci 7:837-849.
22. Kiernan AE, Cordes R, Kopan R, Gossler A, Gridley T (2005) The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 132:4353-4362.
23. Kim TS, Nakagawa T, Endo T, Iguchi F, Murai N, Naito Y, Ito J (2002) Alteration of E-cadherin and beta-catenin in mouse vestibular epithelia during induction of apoptosis. Neurosci Lett 329:173-176.
24. Kim TS, Nakagawa T, Kitajiri S, Endo T, Takebayashi S, Iguchi F, Kita T, Tamura T, Ito J (2005) Disruption and restoration of cell-cell junctions in mouse vestibular epithelia following aminoglycoside treatment. Hear Res 205:201-209.
25. Lanford PJ, Lan Y, Jiang R, Lindsell C, Weinmaster G, Gridley T, Kelley MW (1999) Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet 21:289-292.
26. Li A, Xue J, Peterson EH (2008) Architecture of the mouse utricle: macular organization and hair bundle heights. J Neurophysiol 99:718-733.
27. Lu Z, Corwin JT (2008) The influence of glycogen synthase kinase 3 in limiting cell addition in the mammalian ear. Dev Neurobiol 68:1059-1075.
28. Lumpkin EA, Collisson T, Parab P, Omer-Abdalla A, Haeberle H, Chen P, Doetzlhofer A, White P, Groves A, Segil N, Johnson JE (2003) Math1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expr Patterns 3:389-395.
29. Mbiene JP, Favre D, Sans A (1984) The pattern of ciliary development in fetal mouse vestibular receptors. A qualitative and quantitative SEM study. Anat Embryol (Berl) 170:229-238.
30. Meyers JR, Corwin JT (2007) Shape change controls supporting cell proliferation in lesioned mammalian balance epithelium. J Neurosci 27:4313-4325.
31. Montcouquiol M, Corwin JT (2001) Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase. J Neurosci 21:570-580.
32. Owens DW, Brunton VG, Parkinson EK, Frame MC (2000) E-cadherin at the cell periphery is a determinant of keratinocyte differentiation in vitro. Biochem Biophys Res Commun 269:369-376.
33. Shi F, Cheng YF, Wang XL, Edge AS (2010) Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer. J Biol Chem 285:392-400.
34. Simmons DD, Tong B, Schrader AD, Hawkes AJ (2010) Oncomodulin identifies different hair cell types in the mammalian inner ear. J Comp Neurol 518:3785-3802.
35. Takebayashi S, Yamamoto N, Yabe D, Fukuda H, Kojima K, Ito J, Honjo T (2007) Multiple roles of Notch signaling in cochlear development. Dev Biol 307:165-178.
36. Takeichi M (1993) Cadherins in cancer: implications for invasion and metastasis. Curr Opin Cell Biol 5:806-811.
37. Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelialmesenchymal transitions. Nat Rev Mol Cell Biol 7:131-142.
38. Warchol ME (2007) Characterization of supporting cell phenotype in the avian inner ear: implications for sensory regeneration. Hear Res 227:11-18.
39. Waterman-Storer CM, Salmon WC, Salmon ED (2000) Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cells. Mol Biol Cell 11:2471-2483.
40. Woods C, Montcouquiol M, Kelley MW (2004) Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci 7:1310-1318.
41. Yamamoto N, Tanigaki K, Tsuji M, Yabe D, Ito J, Honjo T (2006) Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med 84:37-45.
42. Zhao S, Fernald RD (2005) Comprehensive algorithm for quantitative realtime polymerase chain reaction. J Comput Biol 12:1047-1064.
43. Zhao Y, Yamoah EN, Gillespie PG (1996) Regeneration of broken tip links and restoration of mechanical transduction in hair cells. Proc Natl Acad Sci U S A 93:15469-15474.
44. Zheng JL, Gao WQ (2000) Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 3:580-586.
45. Zheng JL, Shou J, Guillemot F, Kageyama R, Gao WQ (2000) Hes1 is a negative regulator of inner ear hair cell differentiation. Development 127:4551-4560.