Ischemic preconditioning of the muscle improves maximal exercise performance but not maximal oxygen uptake in humans

Journal of Applied Physiology

Volumn 111, Issue 2, 2011, Pages 530-536

  Crisafulli, Antonio ^a,b   Tangianu, Flavio ^b   Tocco, Filippo ^a   Concu, Alberto ^a   Mameli, Ombretta ^b   Mulliri, Gabriele ^b   Caria, Marcello A ^b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

Author keywords

Muscle contraction; Power output; Reperfusion; Stroke volume

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ADULT; ANAEROBIC THRESHOLD; ARTICLE; BLOOD; EXERCISE; EXERCISE TEST; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HUMAN; ISCHEMIC PRECONDITIONING; MALE; MUSCLE CONTRACTION; MUSCLE STRENGTH; OXYGEN CONSUMPTION; PHYSIOLOGY; REST; SKELETAL MUSCLE;

ADULT; ANAEROBIC THRESHOLD; CARBON DIOXIDE; CARDIAC OUTPUT; EXERCISE; EXERCISE TEST; HEART RATE; HUMANS; ISCHEMIC PRECONDITIONING; MALE; MUSCLE CONTRACTION; MUSCLE STRENGTH; MUSCLE, SKELETAL; OXYGEN; OXYGEN CONSUMPTION; REST; STROKE VOLUME;

EID: 80051749280     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00266.2011     Document Type: Article

References (34)

1. Aman M, Eldridge MW, Lovering AT, Stickland MK, Pegelow DF, Dempsey JA. Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue. J Physiol 575: 937-952, 2006. (Pubitemid 44323753)
2. Asimakis GK, Innerd-McBridge K, Medellin G, Conti VR. Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart. Am J Physiol Heart Circ Physiol 263: H887-H894, 1992.
3. Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60: 2020-2027, 1986. (Pubitemid 16066969)
4. Byard AD, Dengel DR. Validity of a portable metabolic measurement system. Med Sci Sports Exerc 34: S149, 2002.
5. Charloux A, Lonsdorfer-Wolf E, Richard R, Lampert E, Oswald- Mammosser M, Mettauer B, Geny B, Lonsdorfer J. A new impedance cardiograph device for the non-invasive evaluation of cardiac output at rest and during exercise: comparison with the "direct" Fick method. Eur J Appl Physiol 82: 313-320, 2000. (Pubitemid 30599301)
6. Cohen MV, Baines CP, Downey JM. Ischemic preconditioning: from adenosine receptor to KATP channel. Ann Rev Physiol 62: 79-109, 2000. (Pubitemid 30618257)
7. Cohen MV, Yang XM, Downey JM. Smaller infarct after preconditioning does not predict extent of early functional improvement of reperfused heart. Am J Physiol Heart Circ Physiol 277: H1754-H1761, 1999.
8. Crisafulli A. Exercise and ischemic preconditioning. Current Card Rev 2: 153-162, 2006.
9. Crisafulli A, Melis F, Tocco F, Pittau G, Lorrai L, Gori T, Mancardi D, Concu A, Pagliaro P. Delayed preconditioning-mimetic actions of exercise or nitroglycerin do not affect haemodynamics and exercise performance in trained individuals. J Sports Sci 25: 1393-1401, 2007. (Pubitemid 47365188)
10. Crisafulli A, Melis F, Tocco F, Santoboni UM, Lai C, Angioy G, Lorrai L, Pittau G, Concu A, Pagliaro P. Exercise-induced and nitroglycerin- induced myocardial preconditioning improves hemodynamics in patients with angina. Am J Physiol Heart Circ Physiol 287: H235-H242, 2004. (Pubitemid 38802358)
11. Crisafulli A, Milia R, Lobina A, Caddeo M, Tocco F, Concu A, Melis F. Hemodynamic effect of metaboreflex activation in men after running above and below the velocity of the anaerobic threshold. Exp Physiol 93: 447-457, 2008. (Pubitemid 351392987)
12. Crisafulli A, Orrù V, Melis F, Tocco F, Concu A. Hemodynamics during active and passive recovery from a single bout of supramaximal exercise. Eur J Appl Physiol 89: 209-216, 2003. (Pubitemid 36747979)
13. Crisafulli A, Salis E, Pittau G, Lorrai L, Tocco F, Melis F, Pagliaro P, Concu A. Modulation of cardiac contractility by muscle metaboreflex following efforts of different intensities in humans. Am J Physiol Heart Circ Physiol 291: H3035-H3042, 2006. (Pubitemid 44904105)
14. Crisafulli A, Tocco F, Pittau G, Lorrai L, Porru C, Salis E, Pagliaro P, Melis F, Concu A. Effect of differences in post-exercise lactate accumulation in athletes' hemodynamics. Appl Physiol Nutr Metab 31: 423-431, 2006. (Pubitemid 44621787)
15. de Groot PCE, Thijssen DHJ, Sanchez M, Ellenkamp R, Hopman MTE. Ischemic preconditioning improves maximal performance in humans. Eur J Appl Physiol 108: 141-146, 2010.
16. Hargreaves M, McKenna MJ, Jenkins DG, Warmington SA, Li JL, Snow RJ, Febbraio MA. Muscle metabolites and performance during high-intensity, intermittent exercise. J Appl Physiol 84: 1687-1691, 1998. (Pubitemid 28225909)
17. Howley ET, Bassett DR, Welch HG. Criteria for maximal oxygen uptake: review and commentary. Med Sci Sports Exerc 27: 1292-1301, 1995.
18. Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly-trained athletes. Med Sci Sports Exerc. In press.
19. Kitagawa K, Matsumoto M, Tagaya M, Hata R, Ueda H, Niinobe M, Handa N, Fukunaga R, Kimura K, Mokoshiba K, Kamada T. Ischemic tolerance phenomenon found in the brain. Brain Res 528: 21-24, 1990. (Pubitemid 20292932)
20. Lawson CS, Downey JM. Preconditioning: state of the art myocardial protection. Cardiovasc Res 27: 542-550, 1993. (Pubitemid 23144573)
21. Lloris-Carsi JM, Cejalvo D, Toledo-Pereyra LH, Calvo MA, Suzuki S. Preconditioning effect upon lesion modulation in warm liver ischemia. Transplant Proc 25: 3303-3304, 1993. (Pubitemid 24007329)
22. Michaelides AP, Andrikopoulos GK, Oikonomou EV, Psomadaki ZD, Richter DJ, Dilaveris PE, Exadaktylos NI, Stefanadis CI, Toutouzas PK. Improved myocardial performance during repetitive exercise testing: the role of extracellular superoxide dismutase activity in a model of exercise-induced myocardial preconditioning. Am Heart J 146: 160-167, 2003. (Pubitemid 36851316)
23. Mounsey RA, Pang CY, Forrest C. Preconditioning: a new technique for improved muscle flap survival. Otolaryngol Head Neck Surg 107: 549-552, 1992.
24. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136, 1986. (Pubitemid 17174962)
25. Noakes TD. Time to move beyond a brainless exercise physiology: the evidence for complex regulation of human exercise performance. Appl Physiol Nutr Metab 36: 23-35, 2011.
26. Olson TP, Tracy JE, Dengel DR. Validity of a low-flow pneumotach and portable metabolic system for measurement of basal metabolic rate. Med Sci Sports Exerc 35: S143, 2003.
27. Pang CY, Yang RZ, Zhong A, Xu N, Boyd B, Forrest CR. Acute ischemic preconditioning protects against skeletal muscle infarction in the pig. Cardiovasc Res 29: 782-788, 1995.
28. Parratt J, Vegh A. Pronounced antiarrhythmic effects of ischemic preconditioning. Cardioscience 5: 9-18, 1994. (Pubitemid 24110342)
29. Peart JN, Headrick JP. Clinical cardioprotection and the value of conditioning responses. Am J Physiol Heart Circ Physiol 296: H1705-H1720, 2009.
30. Shiki K, Hearse DJ. Preconditioning of ischemic myocardium: reperfusion- induced arrhythmias. Am J Physiol 253: H1470-H1476, 1987.
31. St Clair Gibson A, Noakes TD. Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans. Br J Sports Med 38: 797-806, 2004. (Pubitemid 39611568)
32. Tucker R, Marle T, Lambert EV, Noakes TD. The rate of heat storage mediates an anticipatory reduction in exercise intensity during cycling at a fixed rating of perceived exertion. J Physiol 574: 905-915, 2006. (Pubitemid 44089080)
33. Warburton DER, Haykowsky MJF, Quinney HA, Humen DP, Teo KK. Reliability and validity of measures of cardiac output during incremental to maximal aerobic exercise. Part II: novel techniques and new advances. Sports Med 27: 241-260, 1999. (Pubitemid 29219273)
34. Zager RA, Baltes LA, Sharma HM, Jurkowitz MS. Responses of the ischemic acute renal failure kidney to additional ischemic events. Kidney Int 26: 689-700, 1984. (Pubitemid 15216140)