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Volumn 9, Issue 3, 2011, Pages 159-162

Benzalkonium chloride in glaucoma medications

Author keywords

Benzalkonium chloride; Eye drops; Glaucoma; Ocular toxicity; Preservatives; Topical ocular formulations

Indexed keywords

ANTIGLAUCOMA AGENT; BENZALKONIUM CHLORIDE; BETAXOLOL; EYE DROPS; LATANOPROST; MUCIN; RYSMON TG; TAFLUPROST; TIMOLOL; TIMOLOL MALEATE; TRAVOPROST; UNCLASSIFIED DRUG;

EID: 80051714787     PISSN: 15420124     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1542-0124(11)70025-8     Document Type: Review
Times cited : (41)

References (46)
  • 1
    • 67649981116 scopus 로고    scopus 로고
    • Cytotoxicity of antiglaucoma ophthalmic solutions for human corneal endothelial cells
    • Japanese
    • A yaki M, Noda Y, Yaguchi S, et al. [Cytotoxicity of antiglaucoma ophthalmic solutions for human corneal endothelial cells]. Nippon Ganka Gakkai Zasshi 2009;113:576-82. Japanese
    • (2009) Nippon Ganka Gakkai Zasshi , vol.113 , pp. 576-582
    • Ayaki, M.1    Noda, Y.2    Yaguchi, S.3
  • 2
    • 0024424119 scopus 로고
    • Cytotoxic effects of benzalkonium chloride and chlorobutanol on human corneal epithelial cells in vitro
    • Tripathi BJ, Tripathi RC . Cytotoxic effects of benzalkonium chloride and chlorobutanol on human corneal epithelial cells in vitro. Lens Eye Toxic Res 1989;6:395-403 (Pubitemid 19234248)
    • (1989) Lens and Eye Toxicity Research , vol.6 , Issue.3 , pp. 395-403
    • Tripathi, B.J.1    Tripathi, R.C.2
  • 3
    • 0019967267 scopus 로고
    • Quantitative cytotoxicity of preservatives evaluated in cell culure with Chang's human conjunctival cells. Effect of temperature on cytotoxicity
    • Takahashi N. Quantitative cytotoxicity of preservatives evaluated in cell culture with Chang's human conjunctival cells--effect of temperature on cytotoxicity. Jpn J Ophthalmol 1982;26:234-238 (Pubitemid 12080619)
    • (1982) Japanese Journal of Ophthalmology , vol.26 , Issue.2 , pp. 234-238
    • Takahashi, N.1
  • 4
    • 0027078850 scopus 로고
    • Cytotoxicity of ophthalmic preservatives on human corneal epithelium
    • Tripathi BJ, Tripathi RC, Kolli SP. Cytotoxicity of ophthalmic preservatives on human corneal epithelium. Lens Eye Toxic Res 1992;9:361-375 (Pubitemid 23111708)
    • (1992) Lens and Eye Toxicity Research , vol.9 , Issue.3-4 , pp. 361-375
    • Tripathi, B.J.1    Tripathi, R.C.2    Kolli, S.P.3
  • 7
    • 54049138046 scopus 로고    scopus 로고
    • Cytotoxicity of ophthalmic solutions with and without preservatives to human corneal endothelial cells, epithelial cells and conjunctival epithelial cells
    • A yaki M, Yaguchi S, Iwasawa A, Koide R. Cytotoxicity of ophthalmic solutions with and without preservatives to human corneal endothelial cells, epithelial cells and conjunctival epithelial cells. Clin Experiment Ophthalmol 2008;36:553-559
    • (2008) Clin Experiment Ophthalmol , vol.36 , pp. 553-559
    • Ayaki, M.1    Yaguchi, S.2    Iwasawa, A.3    Koide, R.4
  • 8
    • 33646035223 scopus 로고    scopus 로고
    • Impact of short-term exposure of commercial eyedrops preserved with benzalkonium chloride on precorneal mucin
    • C hung SH, Lee SK, Cristol SM, et al. Impact of short-term exposure of commercial eyedrops preserved with benzalkonium chloride on precorneal mucin. Mol Vis 2006;12:415-21
    • (2006) Mol Vis , vol.12 , pp. 415-421
    • Chung, S.H.1    Lee, S.K.2    Cristol, S.M.3
  • 9
    • 70350440277 scopus 로고    scopus 로고
    • Evaluation of biomarkers of inflammation in response to benzalkonium chloride on corneal and conjunctival epithelial cells
    • E pstein SP, Chen D, Asbell PA. Evaluation of biomarkers of inflammation in response to benzalkonium chloride on corneal and conjunctival epithelial cells. J Ocul Pharmacol Ther 2009;25:415-
    • (2009) J Ocul Pharmacol Ther , vol.25
    • Epstein, S.P.1    Chen, D.2    Asbell, P.A.3
  • 10
    • 78751610662 scopus 로고    scopus 로고
    • Effects of timolol-related ophthalmic solutions on cultured human conjunctival cells
    • Kawase K, Lin W, Aoyama Y, et al. Effects of timolol-related ophthalmic solutions on cultured human conjunctival cells. Jpn J Ophthalmol 2010;54:615-621
    • (2010) Jpn J Ophthalmol , vol.54 , pp. 615-621
    • Kawase, K.1    Lin, W.2    Aoyama, Y.3
  • 11
    • 78650897119 scopus 로고    scopus 로고
    • Preserved and unpreserved 12 anti-allergic ophthalmic solutions and ocular surface toxicity: In vitro assessment in four cultured corneal and conjunctival epithelial cell lines
    • A yaki M, Iwasawa A, Yaguchi S, Koide R. Preserved and unpreserved 12 anti-allergic ophthalmic solutions and ocular surface toxicity: in vitro assessment in four cultured corneal and conjunctival epithelial cell lines. Biocontrol Sci 2010;15:143-148
    • (2010) Biocontrol Sci , vol.15 , pp. 143-148
    • Ayaki, M.1    Iwasawa, A.2    Yaguchi, S.3    Koide, R.4
  • 12
    • 33750974774 scopus 로고    scopus 로고
    • Comparison of the relative toxicity of travoprost 0.004% without benzalkonium chloride and latanoprost 0.005% in an immortalized human cornea epithelial cell culture system
    • Y ee RW, Norcom EG, Zhao XC. Comparison of the relative toxicity of travoprost 0.004% without benzalkonium chloride and latanoprost 0.005% in an immortalized human cornea epithelial cell culture system. Adv Ther 2006;23:511-519
    • (2006) Adv Ther , vol.23 , pp. 511-519
    • Yee, R.W.1    Norcom, E.G.2    Zhao, X.C.3
  • 13
    • 78649320252 scopus 로고    scopus 로고
    • Effects of benzalkonium chloridepreserved, polyquad-preserved, and sofZia-preserved topical glaucoma medications on human ocular epithelial cells
    • A mmar DA, Noecker RJ, Kahook MY. Effects of benzalkonium chloridepreserved, polyquad-preserved, and sofZia-preserved topical glaucoma medications on human ocular epithelial cells. Adv Ther 2010;27:837-845
    • (2010) Adv Ther , vol.27 , pp. 837-845
    • Ammar, D.A.1    Noecker, R.J.2    Kahook, M.Y.3
  • 14
    • 68149132922 scopus 로고    scopus 로고
    • Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells
    • E pstein SP, Ahdoot M, Marcus E, Asbell PA. Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells. J Ocul Pharmacol Ther 2009;25:113-119
    • (2009) J Ocul Pharmacol Ther , vol.25 , pp. 113-119
    • Epstein, S.P.1    Ahdoot, M.2    Marcus, E.3    Asbell, P.A.4
  • 15
    • 3042525205 scopus 로고    scopus 로고
    • A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels
    • DOI 10.1080/10715760410001712773
    • Ingram PR, Pitt AR, Wilson CG, et al. A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels. Free Radic Res 2004;38:739-750 (Pubitemid 38812092)
    • (2004) Free Radical Research , vol.38 , Issue.7 , pp. 739-750
    • Ingram, P.R.1    Pitt, A.R.2    Wilson, C.G.3    Olejnik, O.4    Spickett, C.M.5
  • 16
    • 0026505866 scopus 로고
    • Morphologic and physiologic effects of artificial tear formulations on corneal epithelial derived cells
    • A dams J, Wilcox MJ, Trousdale MD, et al. Morphologic and physiologic effects of artificial tear formulations on corneal epithelial derived cells. Cornea 1992;11:234-41
    • (1992) Cornea , vol.11 , pp. 234-241
    • Adams, J.1    Wilcox, M.J.2    Trousdale, M.D.3
  • 17
    • 0016714516 scopus 로고
    • Effect of benzalkonium chloride on the stabilityof the precorneal tear film in rabbit and man
    • Wilson WS, Duncan AJ, Jay JL. Effect of benzalkonium chloride on the stabilityof the precorneal tear film in rabbit and man. Br J Ophthalmol 1975;59:667-669
    • (1975) Br J Ophthalmol , vol.59 , pp. 667-669
    • Wilson, W.S.1    Duncan, A.J.2    Jay, J.L.3
  • 18
    • 0017608071 scopus 로고
    • Rabbit endothelial response to ophthalmic preservatives
    • Green K, Hull DS, Vaughn ED, et al. Rabbit endothelial response to ophthalmic preservatives. Arch Ophthalmol 1977;95:2218-2221 (Pubitemid 8261065)
    • (1977) Archives of Ophthalmology , vol.95 , Issue.12 , pp. 2218-2221
    • Green, K.1    Hull, D.S.2    Vaughn, E.D.3
  • 19
    • 0020336450 scopus 로고
    • The effect of ophthalmic preservatives on the healing rate of the rabbit corneal epithelium after keratectomy
    • C ollin HB, Grabsch BE. The effect of ophthalmic preservatives on the healing rate of the rabbit corneal epithelium after keratectomy. Am J Optom Physiol Opt 1982;59:215-222
    • (1982) Am J Optom Physiol Opt , vol.59 , pp. 215-222
    • Collin, H.B.1    Grabsch, B.E.2
  • 20
    • 0022606355 scopus 로고
    • Ultrastructural changes to corneal stromal cells due to ophthalmic preservatives
    • C ollin HB. Ultrastructural changes to corneal stromal cells due to ophthalmic preservatives. Acta Ophthalmol (Copenh) 1986;64:72-78
    • (1986) Acta Ophthalmol (Copenh) , vol.64 , pp. 72-78
    • Collin, H.B.1
  • 21
    • 0022692762 scopus 로고
    • Ultrastructural changes to the corneal endothelium due to benzalkonium chloride
    • C ollin HB, Carroll N. Ultrastructural changes to the corneal endothelium due to benzalkonium chloride. Acta Ophthalmol (Copenh) 1986;64:226-231
    • (1986) Acta Ophthalmol (Copenh) , vol.64 , pp. 226-231
    • Collin, H.B.1    Carroll, N.2
  • 22
    • 0025868219 scopus 로고
    • Quantitative evaluation of the corneal epithelial barrier: Effect of artificial tears and preservatives
    • L opez Bernal D, Ubels JL. Quantitative evaluation of the corneal epithelial barrier: effect of artificial tears and preservatives. Curr Eye Res 1991;10:645-656
    • (1991) Curr Eye Res , vol.10 , pp. 645-656
    • Lopez Bernal, D.1    Ubels, J.L.2
  • 23
    • 0026602579 scopus 로고
    • Confocal microscopic studies of living rabbit cornea treated with benzalkonium chloride
    • Erratum in Cornea 1992;11:368
    • Ichijima H, Petroll WM, Jester JV, Cavanagh HD. Confocal microscopic studies of living rabbit cornea treated with benzalkonium chloride. Cornea 1992;11:221-225Erratum in Cornea 1992;11:368
    • (1992) Cornea , vol.11 , pp. 221-225
    • Ichijima, H.1    Petroll, W.M.2    Jester, J.V.3    Cavanagh, H.D.4
  • 24
    • 33749153638 scopus 로고    scopus 로고
    • Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: An experimental study
    • L abbe A, Pauly A, Liang H, et al. Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: an experimental study. J Ocul Pharmacol Ther 2006;22:267-78
    • (2006) J Ocul Pharmacol Ther , vol.22 , pp. 267-278
    • Labbe, A.1    Pauly, A.2    Liang, H.3
  • 25
    • 36949028300 scopus 로고    scopus 로고
    • Acute corneal epithelial change after instillation of benzalkonium chloride evaluated using a newly developed in vivo corneal transepithelial electric resistance measurement method
    • U ematsu M, Kumagami T, Kusano M, et al. Acute corneal epithelial change after instillation of benzalkonium chloride evaluated using a newly developed in vivo corneal transepithelial electric resistance measurement method. Ophthalmic Res 2007;39:308-14
    • (2007) Ophthalmic Res , vol.39 , pp. 308-314
    • Uematsu, M.1    Kumagami, T.2    Kusano, M.3
  • 29
    • 0033966428 scopus 로고    scopus 로고
    • Comparison of the effects of preserved and unpreserved formulations of timolol on the ocular surface of albino rabbits
    • Pisella PJ, Fillacier K, Elena PP, et al. Comparison of the effects of preserved and unpreserved formulations of timolol on the ocular surface of albino rabbits. Ophthalmic Res 2000;32:3-8 (Pubitemid 30093503)
    • (2000) Ophthalmic Research , vol.32 , Issue.1 , pp. 3-8
    • Pisella, P.-J.1    Fillacier, K.2    Elena, P.-P.3    Debbasch, C.4    Baudouin, C.5
  • 30
    • 3042739415 scopus 로고    scopus 로고
    • Corneal and conjunctival changes caused by commonly used glaucoma medications
    • DOI 10.1097/01.ico.0000116526.57227.82
    • Noecker RJ, Herrygers LA, Anwaruddin R. Corneal and conjunctival changes caused by commonly used glaucoma medications. Cornea 2004;23:490-496 (Pubitemid 38857008)
    • (2004) Cornea , vol.23 , Issue.5 , pp. 490-496
    • Noecker, R.J.1    Herrygers, L.A.2    Anwaruddin, R.3
  • 31
    • 69449097521 scopus 로고    scopus 로고
    • Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: An in vivo toxicity assay
    • L iang H, Baudouin C, Faure MO, et al. Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: an in vivo toxicity assay. Mol Vis 2009;15:1690-9
    • (2009) Mol Vis , vol.15 , pp. 1690-1699
    • Liang, H.1    Baudouin, C.2    Faure, M.O.3
  • 32
    • 33845638332 scopus 로고    scopus 로고
    • Assessment of corneal epithelial integrity after acute exposure to ocular hypotensive agents preserved with and without benzalkonium chloride
    • Whitson JT, Cavanagh HD, Lakshman N, Petroll WM. Assessment of corneal epithelial integrity after acute exposure to ocular hypotensive agents preserved with and without benzalkonium chloride. Adv Ther 2006;23:663-671 (Pubitemid 44955845)
    • (2006) Advances in Therapy , vol.23 , Issue.5 , pp. 663-671
    • Whitson, J.T.1    Cavanagh, H.D.2    Lakshman, N.3    Petroll, W.M.4
  • 33
    • 41149179678 scopus 로고    scopus 로고
    • Comparison of corneal and conjunctival changes after dosing of travoprost preserved with sofZia, latanoprost with 0.02% benzalkonium chloride, and preservative-free artificial tears
    • DOI 10.1097/ICO.0b013e31815cf651, PII 0000322620080400000017
    • Kahook MY, Noecker RJ. Comparison of corneal and conjunctival changes after dosing of travoprost preserved with sofZia, latanoprost with 0.02% benzalkonium chloride, and preservative-free artificial tears. Cornea 2008;27:339-343 (Pubitemid 351440870)
    • (2008) Cornea , vol.27 , Issue.3 , pp. 339-343
    • Kahook, M.Y.1    Noecker, R.J.2
  • 34
    • 58749100462 scopus 로고    scopus 로고
    • Quantitative analysis of conjunctival goblet cells after chronic application of topical drops
    • Kahook MY, Noecker R. Quantitative analysis of conjunctival goblet cells after chronic application of topical drops. Adv Ther 2008;25:743-751
    • (2008) Adv Ther , vol.25 , pp. 743-751
    • Kahook, M.Y.1    Noecker, R.2
  • 35
    • 76149146057 scopus 로고    scopus 로고
    • Comparison of corneal wound healing rates after instillation of commercially available latanoprost and travoprost in rat debrided corneal epithelium
    • Nagai N, Murao T, Okamoto N, Ito Y. Comparison of corneal wound healing rates after instillation of commercially available latanoprost and travoprost in rat debrided corneal epithelium. J Oleo Sci 2010;59:135-141
    • (2010) J Oleo Sci , vol.59 , pp. 135-141
    • Nagai, N.1    Murao, T.2    Okamoto, N.3    Ito, Y.4
  • 37
    • 36749021198 scopus 로고    scopus 로고
    • In vivo corneal epithelial permeability following treatment with prostaglandin analoges with or without benzalkonium chloride
    • DOI 10.1089/jop.2007.0024
    • McCarey B, Edelhauser H. In vivo corneal epithelial permeability following treatment with prostaglandin analogs [correction of analoges] with or without benzalkonium chloride. J Ocul Pharmacol Ther 2007;23:445-451 (Pubitemid 350202478)
    • (2007) Journal of Ocular Pharmacology and Therapeutics , vol.23 , Issue.5 , pp. 445-451
    • McCarey, B.1    Edelhauser, H.2
  • 38
    • 0023936023 scopus 로고
    • Toxic endothelial degeneration in ocular surface disease treated with topical medications containing benzalkonium chloride
    • L emp MA, Zimmerman LE . Toxic endothelial degeneration in ocular surface disease treated with topical medications containing benzalkonium chloride. Am J Ophthalmol 1988;105:670-673
    • (1988) Am J Ophthalmol , vol.105 , pp. 670-673
    • Lemp, M.A.1    Zimmerman, L.E.2
  • 40
    • 0025835075 scopus 로고
    • Effects of artificial tears on corneal epithelial permeability in dry eyes
    • Gobbels M, Spitznas M. Effects of artificial tears on corneal epithelial permeability in dry eyes. Graefes Arch Clin Exp Ophthalmol 1991;229:345-349
    • (1991) Graefes Arch Clin Exp Ophthalmol , vol.229 , pp. 345-349
    • Gobbels, M.1    Spitznas, M.2
  • 41
    • 0036282621 scopus 로고    scopus 로고
    • Ocular surface changes induced by topical antiglaucoma monotherapy
    • C venkel B, Ihan A. Ocular surface changes induced by topical antiglaucoma monotherapy. Ophthalmologica 2002;216:175-179
    • (2002) Ophthalmologica , vol.216 , pp. 175-179
    • Cvenkel, B.1    Ihan, A.2
  • 42
    • 0344305387 scopus 로고    scopus 로고
    • Comparison of the Short-Term Effects on the Human Corneal Surface of Topical Timolol Maleate with and without Benzalkonium Chloride
    • DOI 10.1097/00061198-200312000-00008
    • Ishibashi T, Yokoi N, Kinoshita S. Comparison of the short-term effects on thehuman corneal surface of topical timolol maleate with and without benzalkonium chloride. J Glaucoma 2003;12:486-490 (Pubitemid 37494177)
    • (2003) Journal of Glaucoma , vol.12 , Issue.6 , pp. 486-490
    • Ishibashi, T.1    Yokoi, N.2    Kinoshita, S.3
  • 43
    • 1542400618 scopus 로고    scopus 로고
    • Effects of topical antiglaucoma drugs on apoptosis rates of conjunctival epithelial cells in glaucoma patients
    • DOI 10.1046/j.1442-9071.2003.00760.x
    • Dogan AS, Orhan M, Soylemezoǧlu F, et al. Effects of topical antiglaucoma drugs on apoptosis rates of conjunctival epithelial cells in glaucoma patients. Clin Experiment Ophthalmol 2004;32:62-66 (Pubitemid 38344286)
    • (2004) Clinical and Experimental Ophthalmology , vol.32 , Issue.1 , pp. 62-66
    • Dogan, A.S.1    Orhan, M.2    Soylemezoglu, F.3    Irkec, M.4    Bozkurt, B.5
  • 44
    • 77249134758 scopus 로고    scopus 로고
    • Effects of switching to SofZiapreserved travoprost in patients who presented with superficial punctate keratopathy while under treatment with latanoprost
    • Y amazaki S, Nanno M, Kimura T, et al. Effects of switching to SofZiapreserved travoprost in patients who presented with superficial punctate keratopathy while under treatment with latanoprost. Jpn J Ophthalmol 2010;54:7-14
    • (2010) Jpn J Ophthalmol , vol.54 , pp. 7-14
    • Yamazaki, S.1    Nanno, M.2    Kimura, T.3
  • 45
    • 77951758581 scopus 로고    scopus 로고
    • Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication
    • U usitalo H, Chen E, Pfeiffer N, et al. Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication. Acta Ophthalmol 2010;88:329-36
    • (2010) Acta Ophthalmol , vol.88 , pp. 329-336
    • Uusitalo, H.1    Chen, E.2    Pfeiffer, N.3
  • 46
    • 78649694589 scopus 로고    scopus 로고
    • Efficacy and tolerability of preservative- Free eye drops containing a fixed combination of dorzolamide and timolol in glaucoma patients
    • R enieri G, Fuhrer K, Scheithe K, et al. Efficacy and tolerability of preservative- free eye drops containing a fixed combination of dorzolamide and timolol in glaucoma patients. J Ocul Pharmacol Ther 2010;26:597-603
    • (2010) J Ocul Pharmacol Ther , vol.26 , pp. 597-603
    • Renieri, G.1    Fuhrer, K.2    Scheithe, K.3


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