The European Registry on Cushing's syndrome: 2-Year experience. Baseline demographic and clinical characteristics

European Journal of Endocrinology

Volumn 165, Issue 3, 2011, Pages 383-392

  Valassi, Elena ^a   Santos, Alicia ^a   Yaneva, Maria ^b   Tóth, Miklós ^c   Strasburger, Christian J ^d   Chanson, Philippe ^e,f,g   Wass, John A H ^h   Chabre, Olivier ⁱ   Pfeifer, Marija ^j   Feelders, Richard A ^k   Tsagarakis, Stylianos ^l   Trainer, Peter J ^m   Franz, Holger ⁿ   Zopf, Kathrin ^d   Zacharieva, Sabina ^b   Lamberts, StevenWJ ^k   Tabarin, Antoine ^o   Webb, Susan M ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e UNIVERSITÉ PARIS SACLAY   (France)

^f BICÊTRE HOSPITAL   (France)

^g INSERM   (France)

^h CHURCHILL HOSPITAL   (United Kingdom)

ⁱ Service d'Endocrinologie Diabétologie Nutrition   (France)

^j UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^k ERASMUS MEDICAL CENTER   (Netherlands)

^l IASO GENERAL HOSPITAL   (Greece)

^m CHRISTIE HOSPITAL   (United Kingdom)

ⁿ Lohmann and Birkner Health Care Consulting GmbH   (Germany)

^o BORDEAUX UNIVERSITY HOSPITAL   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CLINICAL FEATURE; CONSULTATION; CUSHING SYNDROME; DEMOGRAPHY; DIABETES MELLITUS; EUROPE; FEMALE; FOLLOW UP; HIRSUTISM; HUMAN; INFORMATION PROCESSING; LIBIDO DISORDER; MAJOR CLINICAL STUDY; MALE; MEDICAL SPECIALIST; MENSTRUAL IRREGULARITY; OBSERVATIONAL STUDY; OSTEOPOROSIS; PATIENT CODING; PRIORITY JOURNAL; PROSPECTIVE STUDY; REGISTER; RETROSPECTIVE STUDY; RIB FRACTURE; SEX RATIO; SKIN MANIFESTATION; VERTEBRA FRACTURE; VISUAL ANALOG SCALE; WEIGHT GAIN; BODY MASS; CHILD; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE REGISTRY; HORMONE RELEASE; HYPERTENSION; INFANT; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; QUALITY OF LIFE; SCHOOL CHILD; SMOKING HABIT; ADRENAL TUMOR; CLINICAL TRIAL; COHORT ANALYSIS; FRACTURE; HYPOPHYSIS TUMOR; METABOLIC BONE DISEASE; MIDDLE AGED; PREVALENCE;

CORTICOTROPIN;

ADOLESCENT; ADRENAL GLAND NEOPLASMS; ADULT; AGED; AGED, 80 AND OVER; BONE DISEASES, METABOLIC; COHORT STUDIES; CUSHING SYNDROME; EUROPE; FEMALE; FRACTURES, BONE; HUMANS; MALE; MIDDLE AGED; PITUITARY NEOPLASMS; PREVALENCE; PROSPECTIVE STUDIES; QUALITY OF LIFE; REGISTRIES; RETROSPECTIVE STUDIES;

EID: 80051705162     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-11-0272     Document Type: Article

References (31)

1. Newell-Price J, Bertagna X, Grossman AB & Nieman LK. Cushing's syndrome. Lancet 2006 367 1605-1617. (doi:10.1016/S0140-6736(06)68699-6)
2. Nieman LK, Biller BMK, Findling JW, Newell-Price J, Savage MO, Stewart PM & Montori VM. The diagnosis of Cushing's syndrome: an endocrine society clinical practice guidelines. Journal of Clinical Endocrinology and Metabolism 2008 93 1526-1540. (doi:10.1210/jc.2008-0125)
3. Biller BMK, Grossman AB, Stewart PM, Melmed S, Betagna X, Bertherat J, Buchfelder M, Colao A, Hermus AR, Hofland LJ, Klibanski A, Lacroix A, Lindsay JR, Newell-Price J, Nieman LK, Petersen S, Sonino N, Stalla GK, Swearingen B, Vsmce ML, Wass JAH & Boscaro M. Treatment of adrenocorticotropindependent Cushing's syndrome: a consensus statement. Journal of Clinical Endocrinology and Metabolism 2008 93 2454-2462. (doi:10.1210/jc.2007-2734)
4. Webb SM, Badia X, Barahona MJ, Colao A, Strasburger CJ, Tabarin A, van Aken MO, Pivonello R, Stalla G, Lamberts SW &Glusman JE. Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire. European Journal of Endocrinology 2008 158 623-630. (doi:10.1530/EJE-07-0762)
5. The EuroQoL group. Centre for Health Economics, University of York, UK. EuroQoL - a new facility for the measurement of health-related quality of life. Health Policy 1990 16 199-208. (doi:10.1016/0168-8510(90)90421-9)
6. Wajchenberg BL, Mendonca BB, Liberman B, Pereira MA, Carneiro PC, Wakamatsu A & Kirschner MA. Ectopic adrenocorticotropic hormone syndrome. Endocrine Reviews 1994 15 752-787. (doi:10.1210/edrv-15-6-752)
7. Orth DN. Cushing's syndrome. New England Journal of Medicine 1995 332 791-803. (doi:10.1056/NEJM199503233321207)
8. Invitti C, Pecori Giraldi F, De Martin M & Cavagnini F. Diagnosis and management of Cushing's syndrome: results of an Italian multicentre study. Journal of Clinical Endocrinology and Metabolism 1999 84 440-448. (doi:10.1210/jc.84.2.440)
9. Isidori A, Kaltsas G, Pozza C, Frajese V, Newell-Price J, Reznek RH, Jenkins PJ, Monson JP, Grossman AB & Besser GM. The ectopic adrenocorticotropin syndrome: clinical features, diagnosis, management, and long-term follow-up. Journal of Clinical Endocrinology and Metabolism 2006 91 371-377. (doi:10.1210/jc.2005-1542)
10. Lindhom J, Juul S, Jorgensen JOL, Bjerre AP, Feldt-Rasmussen U, Hagen C, Jorgensen J, Kosteljanetz M, Kristensen LO, Laurberg P, Schmidt K & Weeke J. Incidence and late prognosis of Cushing's syndrome: a population-based study. Journal of Clinical Endocrinology and Metabolism 2001 86 117-123. (doi:10.1210/jc.86.1.117)
11. Ross EJ & Linch DC. Cushing's syndrome-killing disease: discriminatory value of signs and symptoms aiding early diagnosis. Lancet 1982 2 646-649. (doi:10.1016/S0140-6736(82)92749-0)
12. Pecori Giraldi F, Moro M & Cavagnini F. Gender-related differences in the presentation and course of Cushing's disease. Journal of Clinical Endocrinology and Metabolism 2003 88 1554-1558. (doi:10.1210/jc.2002-021518)
13. Ilias I, Torpy DJ, Pacak K, Mullen N, Wesley RA & Nieman LK. Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health. Journal of Clinical Endocrinology and Metabolism 2005 90 4955-4962. (doi:10.1210/jc.2004-2527)
14. Doi M, Sugiyama T, Izumiyama H, Yoshimoto T & Hirata Y. Clinical features and management of ectopic ACTH syndrome at a single institute in Japan. Endocrine Journal 2010 57 1061-1069. (doi:10.1507/endocrj.K10E-265)
15. Salgado LR, Villares Fragoso MCB, Knoepfelmacher M, Machado MC, Domeniece S, Albergaria Pereira MA & Bilharinho de Mendonca B. Ectopic ACTH syndrome: our experience with 25 cases. European Journal of Endocrinology 2006 155 725-733. (doi:10.1530/eje.1.02278)
16. Canalis E, Bilezikian JP, Angeli A & Giustina A. Perspectives on glucocorticoid-induced osteoporosis. Bone 2004 34 593-598. (doi:10.1016/j.bone. 2003.11.026)
17. Barahona MJ, Sucunza N, Resmini E, Fernández-Real JM, Ricart W, Moreno-Navarrete JM, Puig T, Wägner AM, Rodriguez-Espinosa J, Farrerons J & Webb SM. Deleterious effects of glucocorticoid replacement on bone in women after long-term remission of Cushing's syndrome. Journal of Bone and Mineral Research 2009 24 1841-1846. (doi:10.1359/jbmr.090505)
18. Vestergaard P, Lindholm J, Jorgensen JO, Hagen C, Hoeck HC, Laurberg P, Rejnmark L, Brixen K, Kristensen LO, Feldt-Rasmussen U & Mosekilde L. Increased risk of osteoporotic fractures in patients with Cushing's syndrome. European Journal of Endocrinology 2002 146 51-56. (doi:10.1530/eje.0.1460051)
19. Khosla S. Role of hormonal changes in the pathogenesis of osteoporosis in men. Calcified Tissue International 2004 75 110-113. (doi:10.1007/s00223-004- 0290-y)
20. Vierhapper H, Nowotny P & Waldhausl W. Production rates of testosterone in patients with Cushing's syndrome. Metabolism 2000 49 229-231. (doi:10.1016/S0026-0495(00)91429-X)
21. LeBlanc ES, Nielson CM, Marshall LM, Lapidus JA, Barrett- Connor E, Ensrud KE, Hoffman AR, Laughlin G, Ohlsson C &Orwoll ES. The effects of serum testosterone, estradiol, and sex hormone binding globulin levels on fracture risk in older men. Journal of Clinical Endocrinology and Metabolism 2009 94 3337-3346. (doi:10.1210/jc.2009-0206)
22. Orwoll E, Lambert LC, Marshall LM, Blank J, Barrett-Connor E, Cauley J, Ensrund K & Cummings SR. Endogenous testosterone levels, physical performance, and fall risk in older men. Archives of Internal Medicine 2006 166 2124-2131. (doi:10.1001/archinte.166.19.2124)
23. Huizenga NA, Koper JW, De Lange P, Pols HA, Stolk RP, Burger H, Grobbee DE, Brinkmann AO, De Jong FH & Lamberts SW. A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo. Journal of Clinical Endocrinology and Metabolism 1998 83 144-151. (doi:10.1210/jc.83.1.144)
24. Minetto M, Reimondo G, Osella G, Ventura M, Angeli A &Terzolo M. Bone loss is more severe in primary adrenal than in pituitary-dependent Cushing's syndrome. Osteoporosis International 2004 15 855-861. (doi:10.1007/s00198-004- 1616-3)
25. Tauchmanová L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G &Colao A. Bone demineralization and vertebral fractures in endogenous cortisol excess: role of disease etiology and gonadal status. Journal of Clinical Endocrinology and Metabolism 2006 91 1779-1784. (doi:10.1210/jc.2005-0582)
26. Chiodini I, Torlontano M, Carnevale V, Trischitta V & Scillitini A. Skeletal involvement in adult patients with endogenous hypercortisolism. Journal of Endocrinological Investigation 2008 31 267-276. (Pubitemid 351638408)
27. Hawn MT, Cook D, Deveney C & Sheppard BC. Quality of life after laparoscopic bilateral adrenalectomy for Cushing's disease. Surgery 2002 132 1064-1068. (doi:10.1067/msy.2002.128482)
28. Lindsay JR, Nansel T, Baid S, Gumowski J & Nieman LK. Long-term impaired quality of life in Cushing's syndrome despite initial improvement after surgical remission. Journal of Clinical Endocrinology and Metabolism 2006 91 447-453. (doi:10.1210/jc.2005-1058)
29. Johnson MD, Woodburn CJ & Vance ML. Quality of life in patients with a pituitary adenoma. Pituitary 2003 6 81-87. (doi:10.1023/B:PITU.0000004798. 27230.ed)
30. Hans-Helmut K, Bernert S, Angermeyer MC, Matschinger H, Martinez M, Vilagut G, Haro JM, De Girolamo G, de Graaf R, Kovess V & Alonso J & the ESEMeD/MHEDEA. Investigators. Comparison of population health status in six European countries. Medical Care 2000 47 255-261. (doi:10.1097/MLR. 0b013e318184759e)
31. Van Aken MO, Pereira AM, Biermasz NR, van Thiel SW, Hoftijzer HC, Smit JWA, Roelfsema F, Lamberts SWJ &Romijn JA. Quality of life in patients after long-term biochemical cure of Cushing's disease. Journal of Clinical Endocrinology and Metabolism 2005 90 3279-3286. (doi:10.1210/jc.2004-1375)