Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice

Journal of Biological Chemistry

Volumn 286, Issue 33, 2011, Pages 29227-29240

  Patra, Debabrata ^a   DeLassus, Elizabeth ^a   Hayashi, Shinya ^a   Sandell, Linda J ^a  

^a BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE FORMATION; BONE GROWTH; CHONDROCYTE DIFFERENTIATION; CHONDROCYTES; CHONDROPROGENITOR CELLS; ENDOCHONDRAL BONE DEVELOPMENT; GAIN INSIGHT; GROWTH PLATE; KNOCK OUTS; LIPID HOMEOSTASIS; MATRIX; MOUSE MODELS; OSSIFICATION CENTER; RAPID GROWTH; TRABECULAR BONES; TYPE II COLLAGENS; UNFOLDED PROTEIN RESPONSE;

ABLATION; BODY FLUIDS; BONE; CARTILAGE; CELL DEATH; STEM CELLS;

MAMMALS;

CELL PROTEIN; COL10 PROTEIN; COLLAGEN TYPE 2; IHH PROTEIN; PTHRP R PROTEIN; SERINE PROTEINASE; SITE 1 PROTEASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROCYTE HYPERTROPHIC DIFFERENTIATION; CHONDRODYSPLASIA; CONTROLLED STUDY; GENE DELETION; GROWTH PLATE; MOUSE; NEWBORN; NONHUMAN; OSSIFICATION; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; STEM CELL; TRABECULAR BONE;

ANIMALS; CELL DIFFERENTIATION; CHONDROCYTES; COLLAGEN TYPE II; GROWTH PLATE; MICE; MICE, KNOCKOUT; ORGAN SPECIFICITY; OSTEOCHONDRODYSPLASIAS; OSTEOGENESIS; PROPROTEIN CONVERTASES; SERINE ENDOPEPTIDASES; STEM CELLS;

MUS;

EID: 80051698834     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.208686     Document Type: Article

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