Response to concerns about arsenic-induced epithelial to mesenchymal transition and malignant transformation of human bronchial epithelial cells

Toxicological Sciences

Volumn 122, Issue 2, 2011, Pages 607-609

  Yang, Chengfeng ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; CD20 ANTIGEN; CD3 ANTIGEN; GREEN FLUORESCENT PROTEIN; MICRORNA; THYROID TRANSCRIPTION FACTOR 1;

BLADDER CANCER; BRONCHUS MUCOSA; CANCER INVASION; CARCINOGENESIS; CARCINOGENICITY; CELL DIFFERENTIATION; COLONY FORMATION; EPITHELIAL MESENCHYMAL TRANSITION; HISTOPATHOLOGY; HUMAN; IMMUNOFLUORESCENCE; LETTER; LIVER ADENOMA; LIVER CARCINOMA; LUNG TUMOR; MALIGNANT TRANSFORMATION; METASTASIS; NONHUMAN; TOBACCO; TRANSITIONAL CELL CARCINOMA; TUMOR GROWTH; TUMOR XENOGRAFT;

EID: 80051693274     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr151     Document Type: Letter

References (13)

1. Bredfeldt, T. G., Jagadish, B., Eblin, K. E., Mash, E. A., and Gandolfi, A. J. (2006). Monomethylarsonous acid induces transformation of human bladder cells. Toxicol. Appl. Pharmacol. 216, 69-79.
2. Killion, J. J., Radinsky, R., and Fidler, I. J. (1999). Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev. 17, 279-284.
3. Komissarova, E. V., and Rossman, T. G. (2010). Arsenite induced poly(ADPribosyl) ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure. Toxicol. Appl. Pharmacol. 243, 399-404.
4. Li, Y., Ling, M., Xu, Y., Wang, S., Li, Z., Zhou, J., Wang, X., and Liu, Q. (2010). The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite. Toxicol. Sci. 116, 174-182.
5. Reis-Filho, J. S., Carrilho, C., Valenti, C., Leitäo, D., Ribeiro, C. A., Ribeiro, S. G., and Schmitt, F. C. (2000). Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas? Pathol. Res. Pract. 196, 835-840.
6. Rossman, T. G., Uddin, A. N., Burns, F. J., and Bosland, M. C. (2001). Arsenite is a cocarcinogen with solar ultraviolet radiation for mouse skin: an animal model for arsenic carcinogenesis. Toxicol. Appl. Pharmacol. 176, 64-71.
7. Sens, D. A., Park, S., Gurel, V., Sens, M. A., Garrett, S. H., and Somji, S. (2004). Inorganic cadmium- and arsenite-induced malignant transformation of human bladder urothelial cells. Toxicol. Sci. 79, 56-63.
8. Tellez, C. S., Juri, D. E., Do, K., Bernauer, A. M., Thomas, C. L., Damiani, L. A., Tessema, M., Leng, S., and Belinsky, S. A. (2011). EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res. 71, 3087-3097.
9. Turk, A. N., Byer, S. J., Zinn, K. R., and Carroll, S. L. (2011). Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents. J. Vis. Exp. (49), pii: 2558.
10. Waalkes, M. P., Ward, J. M., Liu, J., and Diwan, B. A. (2003). Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice. Toxicol. Appl. Pharmacol. 186, 7-17.
11. Wnek, S. M., Jensen, T. J., Severson, P. L., Futscher, B. W., and Gandolfi, A. J. (2010). Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12 weeks of low-level exposure. Toxicol. Sci. 116, 44-57.
12. Zhao, C. Q., Young, M. R., Diwan, B. A., Coogan, T. P., and Waalkes, M. P. (1997). Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl. Acad. Sci. U.S.A. 94, 10907-10912.
13. Zhao, Y., Tan, Y. S., Haslam, S. Z., and Yang, C. (2010). Perfluorooctanoic acid effects on steroid hormone and growth factor levels mediate stimulation of peripubertal mammary gland development in C57BL/6 mice. Toxicol. Sci. 115, 214-224.