Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas?

Pathology Research and Practice

Volumn 196, Issue 12, 2000, Pages 835-840

  Reis Filho, Jorge S ^a   Carrilho, Carla ^b   Valenti, Carla ^a   Leitaâo, Dina ^a   Ribeiro, Carlos A ^c   Schmitt, Fernando C ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b EDUARDO MONDLANE UNIVERSITY   (Mozambique)

^c Department of Pathology   (Brazil)

Author keywords

Adenocarcinoma; Immunohistochemistry; Lung cancer; Thyroid transcription factor

Indexed keywords

BIOCHEMICAL MARKER; THYROID TRANSCRIPTION FACTOR 1;

ARTICLE; DIFFERENTIAL DIAGNOSIS; EMBRYO DEVELOPMENT; EPITHELIUM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG METASTASIS; MULTIGENE FAMILY; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

EID: 0034520812     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0344-0338(00)80084-9     Document Type: Article

References (13)

1. Thyroid transcription factor-1 is the superior immunohistochemical marker for pulmonary adenocarcinomas and large cell carcinomas compared to surfactant proteins A and B
2. Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma
3. TTF-1 gene expression in human lung tumours
4. Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas
5. Thyroid transcription factor-1 and cytokeratins 7 and 20 in pulmonary and breast carcinoma
6. Immunocytochemical expression of tissue specific transcription factor-1 in lung carcinoma
7. Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor
8. TTF-1 protein expression in pleural malignant mesotheliomas and adenocarcinomas of the lung
9. Value of thyroid transcription factor-1, E-cadherin, BG8, WT1, and CD44S immunostaining in distinguishing epithelial pleural mesothelioma from pulmonary and nonpulmonary adenocarcinoma
10. Determination of lung as the primary site of cerebral metastatic adenocarcinomas using monoclonal antibody to thyroid transcription factor-1
11. Tumors metastatic to lung
12. P53 in breast carcinomas: Association between presence of mutation and immunohistochemical expression using a semi-quantitative approach
13. The World Health Organization histological typing of lung tumors