메뉴 건너뛰기




Volumn 25, Issue 8, 2011, Pages 1229-1235

Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile

Author keywords

cytokines; immune system; immunophenotype; immunotoxicity; mice; Uncaria tomentosa

Indexed keywords

ALCOHOL; ALKALOID; CYTOKINE; OXINDOLE; UNCARIA TOMENTOSA EXTRACT; WATER;

EID: 80051682576     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3549     Document Type: Article
Times cited : (22)

References (29)
  • 2
    • 0242580038 scopus 로고    scopus 로고
    • An extract of Uncaria tomentosa inhibiting cell division and NF-κB activity without inducing cell death
    • DOI 10.1016/j.intimp.2003.07.001
    • Akesson C, Lindgren H, Pero RW,. 2003. An extract of Uncaria tomentosa inhibiting cell division and NFkappaB without inducing cell death. Int Immunopharmacol 3: 1889-1900. (Pubitemid 37421272)
    • (2003) International Immunopharmacology , vol.3 , Issue.13-14 , pp. 1889-1900
    • Akesson, C.1    Lindgren, H.2    Pero, R.W.3    Leanderson, T.4    Ivars, F.5
  • 3
    • 10344259617 scopus 로고    scopus 로고
    • Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100®
    • DOI 10.1016/j.intimp.2004.09.028, PII S1567576904003145, New Trends in Immunosuppression
    • Akesson C, Lindgren H, Pero RW, et al., 2005. Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100. Int Immunopharmacol 5: 219-229. (Pubitemid 39626707)
    • (2005) International Immunopharmacology , vol.5 , Issue.1 , pp. 219-229
    • Akesson, C.1    Lindgren, H.2    Pero, R.W.3    Leanderson, T.4    Ivars, F.5
  • 4
    • 76149105129 scopus 로고    scopus 로고
    • Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB
    • Allen-Hall L, Arnason JT, Cano P, et al., 2010. Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB. J Ethnopharmacol 127: 685-693.
    • (2010) J Ethnopharmacol , vol.127 , pp. 685-693
    • Allen-Hall, L.1    Arnason, J.T.2    Cano, P.3
  • 5
    • 0026038531 scopus 로고
    • Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa
    • Aquino R, De Feo V, De Simone F, et al., 1991. Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa. J Nat Prod 54: 453-459.
    • (1991) J Nat Prod , vol.54 , pp. 453-459
    • Aquino, R.1    De Feo, V.2    De Simone, F.3
  • 6
    • 11844269228 scopus 로고    scopus 로고
    • Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: A mechanism for anti-inflammatory activity
    • DOI 10.1016/j.phytochem.2004.10.025, PII S0031942204005692
    • Gonçalves C, Dinis T, Batista MT,. 2005. Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: a mechanism for anti-inflammatory activity. Phytochemistry 66: 89-98. (Pubitemid 40092730)
    • (2005) Phytochemistry , vol.66 , Issue.1 , pp. 89-98
    • Goncalves, C.1    Dinis, T.2    Batista, M.T.3
  • 8
    • 11844297322 scopus 로고    scopus 로고
    • Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae)
    • DOI 10.1016/j.phytochem.2004.10.022, PII S0031942204005552
    • Heitzman ME, Neto CC, Winiarz E, et al., 2005. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Phytochemistry 66: 5-29. (Pubitemid 40092722)
    • (2005) Phytochemistry , vol.66 , Issue.1 , pp. 5-29
    • Heitzman, M.E.1    Neto, C.C.2    Winiarz, E.3    Vaisberg, A.J.4    Hammond, G.B.5
  • 12
    • 0028205813 scopus 로고
    • Separation of stereoisomeric oxindole alkaloids from Uncaria tomentosa by high performance liquid chromatography
    • DOI 10.1016/0021-9673(94)80511-3
    • Laus G, Keplinger D,. 1994. Separation of stereoisomeric oxindole alkaloids from Uncaria tomentosa by high performance liquid chromatography. J Chromatogr 662: 243-249. (Pubitemid 24075181)
    • (1994) Journal of Chromatography A , vol.662 , Issue.2 , pp. 243-249
    • Laus, G.1    Keplinger, D.2
  • 13
    • 0032993973 scopus 로고    scopus 로고
    • Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa (Una de Gato)
    • DOI 10.1016/S0378-8741(98)00113-5, PII S0378874198001135
    • Lemaire I, Assinnewe V, Cano P, et al., 1999. Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana Uncaria tomentosa (Uña de Gato). J Ethnopharmacol 64: 109-115. (Pubitemid 29130091)
    • (1999) Journal of Ethnopharmacology , vol.64 , Issue.2 , pp. 109-115
    • Lemaire, I.1    Assinewe, V.2    Cano, P.3    Awang, D.V.C.4    Arnason, J.T.5
  • 14
    • 0038679490 scopus 로고    scopus 로고
    • Caracterização e avaliação de populações nativas de Unha-de-gato [Uncaria tomentosa (Willd.) D.C. e U. guianensis (Aubl.) Gmel.] no vale do rio Juruá-AC
    • Miranda E, Sousa J, Pereira R,. 2003. Characterization and evaluation of native populations of Cat's Claw (Uncaria tomentosa and U. guianensis) in the valley of Juruá river, Acre, Brazil. Rev Bras Pl Med 5: 41-46. (Pubitemid 36741073)
    • (2003) Revista Brasileira de Plantas Medicinais , vol.5 , Issue.2 , pp. 41-46
    • De Miranda, E.M.1    De Sousa, J.A.2    Pereira, R.A.3
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T., 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 65: 55-63. (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 17
    • 49749084826 scopus 로고    scopus 로고
    • In vitro cultivated Uncaria tomentosa and Uncaria guianensis with determination of the pentacyclic oxindole alkaloid contents and profiles
    • Pereira RCA, Valente LMM, Pinto JEBP, et al., 2008. In vitro cultivated Uncaria tomentosa and Uncaria guianensis with determination of the pentacyclic oxindole alkaloid contents and profiles. J Braz Chem Soc 19: 1193-1200.
    • (2008) J Braz Chem Soc , vol.19 , pp. 1193-1200
    • Pereira, R.C.A.1    Valente, L.M.M.2    Pinto, J.3
  • 18
    • 39149087954 scopus 로고    scopus 로고
    • Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2
    • Reis SRIN, Valente LMM, Sampaio AL, et al., 2008. Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2. Int Immunopharmacol 8: 468-476.
    • (2008) Int Immunopharmacol , vol.8 , pp. 468-476
    • Reis, S.1    Valente, L.M.M.2    Sampaio, A.L.3
  • 21
    • 0034142139 scopus 로고    scopus 로고
    • Enhanced DNA repair, immune function and reduced toxicity of C-MED-100(TM), a novel aqueous extract from Uncaria tomentosa
    • DOI 10.1016/S0378-8741(99)00070-7, PII S0378874199000707
    • Sheng Y, Bryngelsson C, Pero RW,. 2000. Enhanced DNA repair, immune function and reduced toxicity of C-MED-100, a novel aqueous extract from Uncaria tomentosa. J Ethnopharmacol 69: 115-126. (Pubitemid 30016026)
    • (2000) Journal of Ethnopharmacology , vol.69 , Issue.2 , pp. 115-126
    • Sheng, Y.1    Bryngelsson, C.2    Pero, R.W.3
  • 23
    • 39149105771 scopus 로고    scopus 로고
    • Cat's claw [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis (Aubl.) Gmel.]: An overview of their more relevant aspects
    • Valente LMM,. 2006. Cat's claw [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis (Aubl.) Gmel.]: an overview of their more relevant aspects. Revista Fitos 2: 48-58.
    • (2006) Revista Fitos , vol.2 , pp. 48-58
    • Valente, L.M.M.1
  • 24
    • 38949116925 scopus 로고    scopus 로고
    • Development and application of a thin layer chromatographic method for the determination of the pentacyclic oxindole alkaloid profile in South-American species of the genus Uncaria
    • Valente LMM, Alves FF, Bezerra GM, et al., 2006. Development and application of a thin layer chromatographic method for the determination of the pentacyclic oxindole alkaloid profile in South-American species of the genus Uncaria. Braz J Pharmacog 16: 216-223.
    • (2006) Braz J Pharmacog , vol.16 , pp. 216-223
    • Valente, L.M.M.1    Alves, F.F.2    Bezerra, G.M.3
  • 25
    • 0022227710 scopus 로고
    • DIE ALKALOIDE VON UNCARIA TOMENTOSA UND IHRE PHAGOZYTOSE-STEIGERNDE WIRKUNG
    • Wagner H, Kreutzkamp B, Jurcic K,. 1985. Die alkaloide von Uncaria tomentosa und ihre phagozytose-steigernde Wirkung. Planta Med 5: 419-423. (Pubitemid 16253780)
    • (1985) Planta Medica , vol.NO. 5 , pp. 419-423
    • Wagner, H.1    Kreutzkamp, B.2    Jurcic, K.3
  • 26
    • 1842536367 scopus 로고    scopus 로고
    • In vitro effects of two extracts and two pure alkaloid preparations of Uncaria tomentosa on peripheral blood mononuclear cells
    • DOI 10.1055/s-2004-815536
    • Winkler C, Wirleitner B, Schroecksnadel K, et al., 2004. In vitro effects of two extracts and two pure alkaloid preparations of Uncaria tomentosa on peripheral blood mononuclear cells. Planta Med 70: 205-210. (Pubitemid 38445185)
    • (2004) Planta Medica , vol.70 , Issue.3 , pp. 205-210
    • Winkler, C.1    Wirleitner, B.2    Schroecksnadel, K.3    Schennach, H.4    Mur, E.5    Fuchs, D.6
  • 27
    • 0032406658 scopus 로고    scopus 로고
    • Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferation-regulating factor
    • DOI 10.1055/s-2006-957561
    • Wurm M, Kacani L, Laus G, et al., 1998. Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferating regulating factor. Planta Med 64: 701-704. (Pubitemid 29021565)
    • (1998) Planta Medica , vol.64 , Issue.8 , pp. 701-704
    • Wurm, M.1    Kacani, L.2    Laus, G.3    Keplinger, K.4    Dierich, M.P.5
  • 28
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W, Flavell RA,. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89: 587-596. (Pubitemid 27511769)
    • (1997) Cell , vol.89 , Issue.4 , pp. 587-596
    • Zheng, W.-P.1    Flavell, R.A.2
  • 29
    • 73849110167 scopus 로고    scopus 로고
    • Heterogeneity and plasticity of T helper cells
    • Zhu J, Paul WE,. 2010. Heterogeneity and plasticity of T helper cells. Cell Res 20: 4-12.
    • (2010) Cell Res , vol.20 , pp. 4-12
    • Zhu, J.1    Paul, W.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.