Direct visualization and quantification of bone growth into porous titanium implants using micro computed tomography

Journal of Materials Science: Materials in Medicine

Volumn 22, Issue 5, 2011, Pages 1321-1332

  Baril, E ^a   Lefebvre, L P ^a   Hacking, S A ^b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACKSCATTERED ELECTRON MICROSCOPY; BONE DENSITY; BONE GROWTH; BONE INGROWTH; BONE VOLUME; CEMENTLESS; DATA SETS; DIRECT VISUALIZATION; MICROCOMPUTED TOMOGRAPHY; ORTHOPAEDIC IMPLANTS; PORE OPENINGS; POROUS METAL; POROUS TITANIUM; THREE DIMENSIONAL (3D) IMAGING TECHNIQUES; TIME-CONSUMING PROCESS; TISSUE PROCESSING; TISSUE RESPONSE; TITANIUM FOAMS;

COMPUTERIZED TOMOGRAPHY; HISTOLOGY; THREE DIMENSIONAL; TISSUE; TITANIUM; TOMOGRAPHY; VISUALIZATION;

BONE;

TITANIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACKSCATTERED ELECTRON MICROSCOPY; BONE DENSITY; BONE GROWTH; BONE REGENERATION; EXPERIMENTAL RABBIT; FEMUR; FOAM; HISTOLOGY; IMAGE ANALYSIS; IMPLANT; MALE; MICRO-COMPUTED TOMOGRAPHY; MICROSCOPY; NONHUMAN; POROSITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TIBIA;

ANIMALS; BONE AND BONES; MALE; MICROSCOPY, ELECTRON, SCANNING; PROSTHESES AND IMPLANTS; RABBITS; SURFACE PROPERTIES; TITANIUM; X-RAY MICROTOMOGRAPHY;

ORYCTOLAGUS CUNICULUS;

EID: 80051672430     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-011-4309-4     Document Type: Article

References (29)

1. Della Valle CJ, Mesko NW, Quigley L, Rosenberg AG, Jacobs JJ, Galante JO. Primary total hip arthroplasty with a porous-coated acetabular component. J Bone Joint Surg Am. 2009;91(5):1130-5.
2. Levine BR, Sporera S, Poggie RA, Della Vallea CJ, Jacobs JJ. Experimental and clinical performance of porous tantalum in orthopedic surgery. Biomaterials. 2006;27(27):4671-81. (Pubitemid 43849977)
3. Sporer S, Paprosky WG. The use of a trabecular metal acetabular component and trabecular metal augment for severe acetabular defects. J Arthroplasty. 2006;21(6-suppl):83-6. (Pubitemid 44293259)
4. Ryan G, Pandit A, Apatsidis DP. Fabrication methods of porous metals for use in orthopaedic applications. Biomaterials. 2006;27(13):2651-70. (Pubitemid 43122070)
5. Lefebvre LP, Baril E, Bureau MN. Effect of the oxygen content in solution on the static and cyclic deformation of titanium foams. J Mater Sci: Mater Med. 2009;20(11):2223-33.
6. Zhang Y, Ahn PB, Fitzpatrick DC, Heiner AD, Poggie RA, Brown TD. Interfacial frictional behavior: cancellous bone, cortical bone, and a novel porous tantalum biomaterial. J Musculoskeletal Res. 1999;3(4):245-51.
7. Heiner AD, Brown TD. Frictional coefficients of a new bone ingrowth structure. Trans Orthopaed Res Soc. 2007;32:1623.
8. Boyde A, Jones SJ. Back-scattered electron imaging of skeletal tissues. Metab Bone Dis Relat Res 1983-1984;5(3):145-50. (Pubitemid 14143238)
9. Assad M, Jarzem P, Leroux MA, Couillard C, Chernyshov AV, Charrette S, Rivard CH. Porous titanium-nickel for intervertebral fusion in a sheep model: part 1. Histomorphometric and radiological analyses. J Biomed Mater Res B Appl Biomater. 2003;64B(2):107-20. (Pubitemid 37517145)
10. Odgaard A, Gundersen HJG. Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstruction. Bone. 1993;14(2):173-82. (Pubitemid 23098966)
11. Feldkamp LA, Goldstein SA, Parfitt M, Jesion G, Kleerekoper M. The direct examination of three-dimensional bone architecture in vitro by computed tomography. J Bone Miner Res. 1989;4(1):3-11. (Pubitemid 19079118)
12. Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 2010;25(7):1468-86.
13. Gebauer M, Barvencik F, Mumme M, Beil FT, Vettorazzi E, Rueger JM, et al. Microarchitecture of the radial head and its changes in aging. Calcif Tissue Int. 2010;86(1):14-22.
14. Zhang ZM, Li ZC, Jiang LS, Jiang SD, Dai LY. Micro-CT and mechanical evaluation of subchondral trabecular bone structure between postmenopausal women with osteoarthritis and osteoporosis. Osteoporos Int. 2009;21(8):1383-90.
15. Bonse U, Busch F, Günnewig O, Beckmann F, Pahl R, Delling G, et al. 3D computed X-ray tomography of human cancellous bone at 8 microns spatial and 10 (-4) energy resolution. Bone Miner. 1994;25(1):25-38. (Pubitemid 24146129)
16. Kirby BJ, Davis JR, Grant JA, Morgan MJ. Monochromatic microtomographic imaging of osteoporotic bone. Phys Med Biol. 1997;42(7):1375-85. (Pubitemid 27315977)
17. Bernhardt R, Scharnweber D, Müller B, Thurner P, Schliephake H, Wyss P, et al. Comparison of microfocus and synchrotron X-ray tomography for the analysis of osseontegration around Ti6Al4 V-implants. Euro Cell Mater. 2004;7:42-51. (Pubitemid 39347335)
18. Bobyn JD, Pilliar RM, Cameron HU, Weatherly GC. The optimum pore size, for the fixation of porous-surfaced metal implants by the ingrowth of bone. Clin Orthop Relat Res. 1980;150:263-70. (Pubitemid 10039063)
19. Baril E, Lefebvre LP, Piché N. X-ray microtomographic visualization and quantification of metallic foam structure filled with second phases-examples in biomedical applications. The proceeding of the 6th Int. Conf on Porous Metals and Metallic Foams (Metfoam 2009); 2009 Sep. 1-4; Bratislava, Slovakia.
20. Otsuki B, Takemoto M, Fujibayashi S, Neo M, Kokubob T, Nakamura T. Pore throat size and connectivity determine bone and tissue ingrowth into porous implants: three-dimensional micro-CT based structural analyses of porous bioactive titanium implants. Biomaterials. 2006;27(35):5892-900. (Pubitemid 44332516)
21. Jones AC, Arns CH, Sheppard AP, Hutmacher DW, Milthorpe K, Knacksted MA. Assessment of bone ingrowth into porous biomaterials using MICRO-CT. Biomaterials. 2007;28(15):2491-504. (Pubitemid 46365916)
22. Lefebvre LP, Thomas Y. Method of making open cell material. US Patent No. 6, 660, 224 B2, 2003.
23. Wazen R, Lefebvre LP, Baril E, Nanci A. Initial evaluation of bone ingrowth into a novel porous titanium coating. J Biomed Mat Res-Part B. 2010;94(1):64-71.
24. Gauthier M, Menini R, Bureau MN, So SKV, Dion MJ, Lefebvre LP. Properties of novel titanium foams intended for biomedical applications. ASM Materials and Processes for Medical Devices Conference, 2003 Sep. 8-10; Anaheim, California: 382-387.
25. Hacking SA, Bobyn JD, Tanzer M, Krygier JJ. The osseous response to corundum blasted implant surfaces in a canine hip model. Clin Orthop. 1999;364:240-53. (Pubitemid 29334008)
26. Hacking SA, Harvey EJ, Tanzer M, Bobyn JD, Krygier JJ. Acid etched microtexture for enhancement of bone growth into porous coated implants. J Bone Joint Surg. 2003;85(8):1182-9. (Pubitemid 37461416)
27. Habibovic P, de Groot K. Osteoinductive biomaterials-properties and relevance in bone repair. J Tissue Eng Regen Med. 2007;1(1):25-32.
28. Hsieh J. Computed tomography: principles, design, artifacts, and recent advances. 2nd ed. Bellingham, New York: SPIE Press and Wiley; 2009.
29. Sethian JA. Level set methods and fast marching methods: evolving interfaces in computational geometry, fluid mechanics, computer vision, and materials science. 2nd ed. Cambridge: Cambridge University Press; 1999.