메뉴 건너뛰기




Volumn 31, Issue 9, 2011, Pages 2999-3005

Lapatinib enhances herceptin-mediated antibody-dependent cellular cytotoxicity by up-regulation of cell surface HER2 expression

Author keywords

ADCC; Breast cancer; HER2; Herceptin; Lapatinib

Indexed keywords

ANASTROZOLE; CA 15-3 ANTIGEN; CAPECITABINE; CYCLOPHOSPHAMIDE; DIMETHYL SULFOXIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; LAPATINIB; NCC ST439; PROGESTERONE RECEPTOR; RITUXIMAB; TRASTUZUMAB; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 80051643188     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (25)
  • 1
    • 0022399581 scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, McGrath J, Seeburg PH, Libermann TA, Schlessinger J, Francke U, Levinson A and Ullrich A: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 230: 1132-1139, 1985. (Pubitemid 16169997)
    • (1985) Science , vol.230 , Issue.4730 , pp. 1132-1139
    • Coussens, L.1    Yang-Feng, T.L.2    Liao, Y.-C.3
  • 2
    • 0034255737 scopus 로고    scopus 로고
    • HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes
    • DOI 10.1002/1097-0215(20000801)87:3<349::AID-IJC7>3.0.CO;2-O
    • Seliger B, Rongcun Y, Atkins D, Hammers S, Huber C, Storkel S and Kiessling R: HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. Int J Cancer 87: 349-359, 2000. (Pubitemid 30451645)
    • (2000) International Journal of Cancer , vol.87 , Issue.3 , pp. 349-359
    • Seliger, B.1    Rongcun, Y.2    Atkins, D.3    Hammers, S.4    Huber, C.5    Storkel, S.6    Kiessling, R.7
  • 3
    • 18044376819 scopus 로고    scopus 로고
    • Frequencies of HER-2/neu expression and gene amplification in patients with oesophageal squamous cell carcinoma
    • DOI 10.1038/sj.bjc.6602499
    • Mimura K, Kono K, Hanawa M, Mitsui F, Sugai H, Miyagawa N, Ooi A and Fujii H: Frequencies of HER-2/neu expression and gene amplification in patients with oesophageal squamous cell carcinoma. Br J Cancer 92: 1253-1260, 2005. (Pubitemid 40604400)
    • (2005) British Journal of Cancer , vol.92 , Issue.7 , pp. 1253-1260
    • Mimura, K.1    Kono, K.2    Hanawa, M.3    Mitsui, F.4    Sugai, H.5    Miyagawa, N.6    Ooi, A.7    Fujii, H.8
  • 5
    • 0037140070 scopus 로고    scopus 로고
    • Status of c-erbB-2 in gastric adenocarcinoma: A comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assay
    • DOI 10.1002/ijc.10257
    • Takehana T, Kunitomo K, Kono K, Kitahara F, Iizuka H, Matsumoto Y, Fujino MA and Ooi A: Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immunosorbent assay. Int J Cancer 98: 833-837, 2002. (Pubitemid 34286677)
    • (2002) International Journal of Cancer , vol.98 , Issue.6 , pp. 833-837
    • Takehana, T.1    Kunitomo, K.2    Kono, K.3    Kitahara, F.4    Iizuka, H.5    Matsumoto, Y.6    Fujino, M.A.7    Ooi, A.8
  • 9
    • 0037149539 scopus 로고    scopus 로고
    • Herceptin acts as an anti-angiogenic cocktail
    • Izumi Y, Xu L, di Tomaso E, Fukumura D and Jain RK: Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature 416: 279-280, 2002. (Pubitemid 34260234)
    • (2002) Nature , vol.416 , Issue.6878 , pp. 279-280
    • Izumi, Y.1    Xu, L.2    Di, T.E.3    Fukumura, D.4    Jain, R.K.5
  • 10
    • 0035874898 scopus 로고    scopus 로고
    • Down-regulation of the erbB-2 receptor by trastuzumab (Herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
    • Cuello M, Ettenberg SA, Clark AS, Keane MM, Posner RH, Nau MM, Dennis PA and Lipkowitz S: Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res 61: 4892-4900, 2001. (Pubitemid 32691907)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4892-4900
    • Cuello, M.1    Ettenberg, S.A.2    Clark, A.S.3    Keane, M.M.4    Posner, R.H.5    Nau, M.M.6    Dennis, P.A.7    Lipkowitz, S.8
  • 11
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • DOI 10.1038/74704
    • Clynes RA, Towers TL, Presta LG and Ravetch JV: Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 6: 443-446, 2000. (Pubitemid 30208162)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 12
    • 0037108686 scopus 로고    scopus 로고
    • Impaired antibody-dependent cellular cytotoxicity mediated by Herceptin in patients with gastric cancer
    • Kono K, Takahashi A, Ichihara F, Sugai H, Fujii H and Matsumoto Y: Impaired antibody-dependent cellular cytotoxicity mediated by Herceptin in patients with gastric cancer. Cancer Res 62: 5813-5817, 2002. (Pubitemid 35204740)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5813-5817
    • Kono, K.1    Takahashi, A.2    Ichihara, F.3    Sugai, H.4    Fujii, H.5    Matsumoto, Y.6
  • 13
    • 27244450053 scopus 로고    scopus 로고
    • Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma
    • DOI 10.1158/1078-0432.CCR-04-2476
    • Mimura K, Kono K, Hanawa M, Kanzaki M, Nakao A, Ooi A and Fujii H: Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma. Clin Cancer Res 11: 4898-4904, 2005. (Pubitemid 41557210)
    • (2005) Clinical Cancer Research , vol.11 , Issue.13 , pp. 4898-4904
    • Mimura, K.1    Kono, K.2    Hanawa, M.3    Kanzaki, M.4    Nakao, A.5    Ooi, A.6    Fujii, H.7
  • 17
    • 31544457665 scopus 로고    scopus 로고
    • Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis
    • DOI 10.1158/0008-5472.CAN-05-2506
    • Zhou Y, Li S, Hu YP, Wang J, Hauser J, Conway AN, Vinci MA, Humphrey L, Zborowska E, Willson JK and Brattain MG: Blockade of EGFR and ERBB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis. Cancer Res 66: 404-411, 2006. (Pubitemid 43166048)
    • (2006) Cancer Research , vol.66 , Issue.1 , pp. 404-411
    • Zhou, Y.1    Li, S.2    Hu, Y.P.3    Wang, J.4    Hauser, J.5    Conway, A.N.6    Vinci, M.A.7    Humphrey, L.8    Zborowska, E.9    Willson, J.K.V.10    Brattain, M.G.11
  • 19
    • 79958856696 scopus 로고    scopus 로고
    • Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody-dependent cellular cytoxicity (ADCC) of EGFR and HER2 overexpressing esophageal cancer cell lines
    • 8 APR DOI: 10.1002/ijc.25896
    • Mimura K, Kono K, Maruyama T, Watanabe M, Izawa S, Shiba S, Mizukami Y, Kawaguchi Y, Inoue M, Kono T, Choudhury A, Kiessling R and Fujii H: Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody-dependent cellular cytoxicity (ADCC) of EGFR and HER2 overexpressing esophageal cancer cell lines. Int J Cancer: 8 APR 2011, DOI: 10.1002/ijc.25896.
    • (2011) Int J Cancer
    • Mimura, K.1    Kono, K.2    Maruyama, T.3    Watanabe, M.4    Izawa, S.5    Shiba, S.6    Mizukami, Y.7    Kawaguchi, Y.8    Inoue, M.9    Kono, T.10    Choudhury, A.11    Kiessling, R.12    Fujii, H.13
  • 25
    • 30544450275 scopus 로고    scopus 로고
    • Combining lapatinib (GW572016), a small molecule inhibitor of ERBB1 and ERBB2 tyrosine kinases, with therapeutic anti-ERBB2 antibodies enhances apoptosis of ERBB2-overexpressing breast cancer cells
    • Xia W, Gerard CM, Liu L, Baudson NM, Ory TL and Spector NL: Combining lapatinib (GW572016), a small molecule inhibitor of ERBB1 and ERBB2 tyrosine kinases, with therapeutic anti-ERBB2 antibodies enhances apoptosis of ERBB2-overexpressing breast cancer cells. Oncogene 24: 6213-6221, 2005.
    • (2005) Oncogene , vol.24 , pp. 6213-6221
    • Xia, W.1    Gerard, C.M.2    Liu, L.3    Baudson, N.M.4    Ory, T.L.5    Spector, N.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.