Hyperthermia inhibits platelet hemostatic functions and selectively regulates the release of alpha-granule proteins

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 8, 2011, Pages 1562-1571

  Etulain, J ^a   Lapponi, M J ^a   Patrucchi, S J ^a   Romaniuk, M A ^a   Benzadon R ^b   Klement, G L ^c,d   Negrotto, Soledad ^a   Schattner, Mirta ^a  

^a Universidad Nacional de Río Cuarto Consejo Nacional de Investigaciones Científicas y Técnicas   (Argentina)

^b CEMIC   (Argentina)

^c TUFTS MEDICAL CENTER   (United States)

^d ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

Alpha granule secretion; Hyperthermia; Inflammation; Platelet aggregation; Platelets; Temperature

Indexed keywords

ADENOSINE TRIPHOSPHATE; CD63 ANTIGEN; ENDOSTATIN; I KAPPA B; PADGEM PROTEIN; PROTEIN KINASE SYK; STEROID RECEPTOR COACTIVATOR 1; SYNAPTOPHYSIN; THROMBOXANE A2; VASCULOTROPIN; VON WILLEBRAND FACTOR;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEMOSTASIS; HIGH TEMPERATURE; HUMAN; HYPERTHERMIA; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; TEMPERATURE DEPENDENCE; THROMBOCYTE; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; TURBIDIMETRY;

ADENOSINE TRIPHOSPHATE; BLOOD PLATELETS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEVER; FLOW CYTOMETRY; HEMOSTASIS; HOT TEMPERATURE; HUMANS; MICROSCOPY, FLUORESCENCE; NEPHELOMETRY AND TURBIDIMETRY; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASES; SECRETORY VESICLES; SIGNAL TRANSDUCTION; THROMBIN; THROMBOXANE A2; TIME FACTORS;

EID: 80051595343     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04394.x     Document Type: Article

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