Patients' understanding of clinical trials needs to be assessed in the context of understanding of overall goals of care

Supportive Care in Cancer

Volumn 19, Issue 8, 2011, Pages 1067-1068

  Yoong, Jaclyn ^a,b   Jefford, Michael ^a   Mileshkin, Linda ^a  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b Unit 805   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATTITUDE TO HEALTH; CANCER CONTROL; CANCER DIAGNOSIS; CANCER GRADING; CANCER LOCALIZATION; CANCER PREVENTION; CANCER THERAPY; CLINICAL ASSESSMENT; CLINICAL DECISION MAKING; CLINICAL TRIAL (TOPIC); CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; DISEASE SEVERITY; HUMAN; INFORMATION DISSEMINATION; INFORMED CONSENT; INTERPERSONAL COMMUNICATION; LETTER; METASTASIS; ORGANIZATION; PATIENT ATTITUDE; PATIENT CARE; PATIENT INFORMATION; PATIENT SATISFACTION; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; QUALITY OF LIFE; SCORING SYSTEM; SIDE EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

CLINICAL TRIALS AS TOPIC; FEMALE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALE; PATIENT SATISFACTION; RESEARCH SUBJECTS;

EID: 80051577655     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-011-1201-1     Document Type: Letter

References (14)

1. M Jefford L Mileshkin J Matthews H Raunow C O'Kane T Cavicchiolo, et al. 2011 Satisfaction with the decision to participate in cancer clinical trials is high, but understanding is a problem Support Care Cancer 19 3 371 379 20333413 10.1007/s00520-010-0829-6 1:STN:280:DC%2BC3M3it1ektQ%3D%3D
2. S Joffe EF Cook PD Cleary JW Clark JC Weeks 2001 Quality of informed consent: a new measure of understanding among research subjects J Natl Cancer Inst 93 2 139 147 11208884 10.1093/jnci/93.2.139 1:STN:280: DC%2BD3M7nvF2lug%3D%3D (Pubitemid 32111992)
3. S Joffe EF Cook PD Cleary JW Clark JC Weeks 2001 Quality of informed consent in cancer clinical trials: a cross-sectional survey Lancet 358 9295 1772 1777 11734235 10.1016/S0140-6736(01)06805-2 1:STN:280:DC%2BD3MnoslOktQ%3D%3D (Pubitemid 33153003)
4. E Beardsley M Jefford L Mileshkin 2007 Longer consent forms for clinical trials compromise patient understanding: so why are they lengthening? J Clin Oncol 25 9 e13 e14 17369564 10.1200/JCO.2006.10.3341
5. SA Grossman S Piantadosi C Covahey 1994 Are informed consent forms that describe clinical oncology research protocols readable by most patients and their families? J Clin Oncol 12 10 2211 2215 7931491 1:STN:280: DyaK2M%2Fhs1yrug%3D%3D (Pubitemid 24356041)
6. PS Craft CM Burns WT Smith DH Broom 2005 Knowledge of treatment intent among patients with advanced cancer: a longitudinal study Eur J Cancer Care (Engl) 14 5 417 425 10.1111/j.1365-2354.2005.00601.x 1:STN:280: DC%2BD2Mrps1Siug%3D%3D (Pubitemid 41695944)
7. RN Eidinger DV Schapira 1984 Cancer patients' insight into their treatment, prognosis, and unconventional therapies Cancer 53 12 2736 2740 6326993 10.1002/1097-0142(19840615)53:12<2736::AID-CNCR2820531233>3.0. CO;2-W 1:STN:280:DyaL2c3gsFansw%3D%3D (Pubitemid 14112914)
8. M Gattellari PN Butow MH Tattersall SM Dunn CA MacLeod 1999 Misunderstanding in cancer patients: why shoot the messenger? Ann Oncol 10 1 39 46 10076720 10.1023/A:1008336415362 1:STN:280:DyaK1M7ns1SitA%3D%3D (Pubitemid 29090590)
9. WJ Mackillop WE Stewart AD Ginsburg SS Stewart 1988 Cancer patients' perceptions of their disease and its treatment Br J Cancer 58 3 355 358 2460120 10.1038/bjc.1988.218 1:STN:280:DyaL1M%2Fis1KjsA%3D%3D
10. P Pronzato G Bertelli P Losardo M Landucci 1994 What do advanced cancer patients know of their disease? A report from Italy Support Care Cancer 2 4 242 244 7522106 10.1007/BF00365729 1:STN:280:DyaK2czntlemsw%3D%3D
11. M Jefford R Moore 2008 Improvement of informed consent and the quality of consent documents Lancet Oncol 9 5 485 493 18452859 10.1016/S1470-2045(08) 70128-1 (Pubitemid 351597797)
12. MH Tattersall M Gattellari K Voigt PN Butow 2002 When the treatment goal is not cure: are patients informed adequately? Support Care Cancer 10 4 314 321 12029431 10.1007/s005200100291 (Pubitemid 36056286)
13. LA Jansen PS Appelbaum WM Klein ND Weinstein W Cook JS Fogel, et al. 2011 Unrealistic optimism in early-phase oncology trials IRB 33 1 1 8 21314034
14. JC Weeks EF Cook SJ O'Day LM Peterson N Wenger D Reding, et al. 1998 Relationship between cancer patients' predictions of prognosis and their treatment preferences JAMA 279 21 1709 1714 9624023 10.1001/jama.279.21.1709 1:STN:280:DyaK1c3osFGjtg%3D%3D (Pubitemid 28247301)