Novel method for quantifying radiation-induced single-strand-break yields in plasmid DNA highlights 10-fold discrepancy

Analytical Biochemistry

Volumn 417, Issue 2, 2011, Pages 242-246

  Balagurumoorthy, Pichumani ^a   James Adelstein, S ^a   Kassis, Amin I ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Endonucleases; Plasmids; Radiation; Single strand breaks; Rays

Indexed keywords

BIOMOLECULES; ELECTROPHORESIS; GAMMA RAYS; HEAT RADIATION;

AGAROSE GEL ELECTROPHORESIS; CONVENTIONAL METHODS; ENDONUCLEASES; IRRADIATED SAMPLES; PLASMIDS; RADIATION RISK; RADIATION-INDUCED; SINGLE-STRAND BREAKS;

DNA;

ADENOSINE TRIPHOSPHATE; AGAROSE; ALKALI; DNA; PHOSPHORUS 32; PLASMID DNA; TRITIUM;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DENATURATION; DNA DAMAGE; DNA DETERMINATION; DNA SUPERCOILING; GAMMA RADIATION; IRRADIATION; MOLECULAR PROBE; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RADIATION DOSE; SINGLE STRANDED DNA BREAK;

EID: 80051547355     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.06.023     Document Type: Article

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