The balance between mutators and nonmutators in asexual populations

Genetics

Volumn 188, Issue 4, 2011, Pages 997-1014

  Desai, Michael M ^a   Fisher, Daniel S ^b  

^a HARVARD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ALLELIC IMBALANCE; ARTICLE; ASEXUAL REPRODUCTION; ELIMINATION REACTION; EVOLUTION; GENE MUTATION; GENETIC ANALYSIS; MOLECULAR DYNAMICS; MUTATOR GENE; NONMUTATOR GENE; POPULATION DYNAMICS; PRIORITY JOURNAL;

ALGORITHMS; ALLELES; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; GENETIC FITNESS; MODELS, GENETIC; MUTATION; PROBABILITY; REPRODUCTION, ASEXUAL;

EID: 80051529629     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.111.128116     Document Type: Article

References (55)

1. Andre, J.-B., and B. Godelle, 2006 The evolution of mutation rate in finite asexual populations. Genetics 172: 611-626.
2. Baer, C. F., M. M. Miyamoto, and D. R. Denver, 2007 Mutation rate variation in multicellular eukaryotes: causes and consequences. Nat. Rev. Genet. 8: 619-631.
3. Bjorkholm, B., M. Sjolund, P. G. Falk, O. G. Berg, L. Engstrand et al., 2001 Mutation frequency and biological cost of antibiotic resistance in helicobacter pylori. Proc. Natl. cad. Sci. USA 98: 14607-14612.
4. Boe, L., M. Danielsen, S. Knudsen, J. B. Petersen, J. Maymann et al., 2000 The frequency of mutators in populations of Escherichia coli. Mutat. Res. 448: 47-55.
5. Chao, L., and E. C. Cox, 1983 Competition between high and low mutating strains of Escherichia coli. Evolution 37: 125-134.
6. Chao, L., C. Vargas, B. B. Spear, and E. C. Cox, 1983 Transposable elements as mutator genes in evolution. Nature 303: 633-635.
7. Cox, E. C., and T. C. Gibson, 1974 Selection for high mutation rates in chemostats. Genetics 77: 169-184.
8. Dawson, K. J., 1998 Evolutionarily stable mutation rates. J. Theor. Biol. 194: 143-157.
9. Dawson, K. J., 1999 The dynamics of infinitesimally rare alleles, applied to the evolution of mutation rates and the expression of deleterious mutations. Theor. Popul. Biol. 55: 1-22.
10. del Campo, R., M. I. Morosini, E. G. G. de la Pedrosa, A. Fenoll, C. Munoz-Almagro et al., 2005 Population structure, antimicrobial resistance, and mutation frequencies of Streptococcus pneumoniae isolates from cystic fibrosis patients. J. Clin. Microbiol. 43: 2207-2214.
11. Denamur, E., and I. Matic, 2006 Evolution of mutation rates in bacteria. Mol. Microbiol. 60: 820-827.
12. Denamur, E., G. Lecointre, P. Darlu, O. Tenaillon, C. Acquaviva et al., 2000 Evolutionary implications of the frequent horizontal transfer of mismatch repair genes. Cell 103: 711-721.
13. Denamur, E., S. Bonacorsi, A. Giraud, P. Duriez, F. Hilali et al., 2002 High frequency of mutator strains among human uropathogenic Escherichia coli isolates. J. Bacteriol. 184: 605-609.
14. Denamur, E., O. Tenaillon, C. Deschamps, D. Skurnik, E. Ronco et al., 2005 Intermediate mutation frequencies favor evolution of multidrug resistance in escherichia coli. Genetics 171: 825-827.
15. Desai, M. M., and D. S. Fisher, 2007 Beneficial mutation-selection balance and the effect of linkage on positive selection. Genetics 176: 1759-1798.
16. Ewens, W. J., 2004 Mathematical Population Genetics. I. Theoretical Introduction. Springer, New York, NY.
17. Gerrish, P. J., A. Colato, A. S. Perelson, and P. D. Sniegowski, 2007 Complete genetic linkage can subvert natural selection. Proc. Natl. Acad. Sci. USA 104: 6266-6271.
18. Gillespie, J. H., 1981 Mutation modification in a random environment. Evolution 35: 468-476.
19. Giraud, A., I. Matic, O. Tenaillon, A. Clara, M. Radman et al., 2001 Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut. Science 291: 2606-2608.
20. Giraud, A., I. Matic, M. Radman, M. Fons, and F. Taddei, 2002 Mutator bacteria as a risk factor in treatment of infectious diseases. Antimicrob. Agents Chemother. 46: 863-865.
21. Gross, M. D., and E. C. Siegel, 1981 Incidence of mutator strains in Escherichia coli and coliforms in nature. Mutat. Res. 91: 107-110.
22. Haigh, J., 1978 The accumulation of deleterious genes in a population: Muller's ratchet. Theor. Popul. Biol. 14: 251-267.
23. Ishii, K., H. Matsuda, Y. Iwasa, and A. Sasaki, 1989 Evolutionarily stable mutation rate in a periodically changing environment. Genetics 121: 163-174.
24. Johnson, T., 1999a The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates. Proc. Biol. Sci. 266: 2389-2397.
25. Johnson, T., 1999b Beneficial mutations, hitchhiking and the evolution of mutation rates in sexual populations. Genetics 151: 1621-1631.
26. Johnson, T., and N. H. Barton, 2002 The effect of deleterious alleles on adaptation in asexual populations. Genetics 162: 395-411.
27. Kimura, M., 1967 On the evolutionary adjustment of spontaneous mutation rates. Genet. Res. 9: 23-34.
28. Kimura, M., and T. Maruyama, 1966 The mutational load with epistatic gene interactions in fitness. Genetics 54: 1337-1351.
29. Labat, F., O. Pradillon, L. Garry, M. Peuchmaur, B. Fantin et al., 2005 Mutator phenotype confers advantage in escherichia coli chronic urinary tract infection pathogenesis. FEMS Immunol. Med. Microbiol. 44: 317-321.
30. LeClerc, J. E., B. G. Li, W. L. Payne, and T. A. Cebula, 1996 High mutation frequencies among Escherichia coli and Salmonella pathogens. Science 274: 1208-1211.
31. LeClerc, J. E., W. L. Payne, E. Kupchella, and T. A. Cebula, 1998 Detection of mutator subpopulations in salmonella typhimurium lt2 by reversion of his alleles. Mutat. Res. 400: 89-97.
32. Leigh, E. G., 1970 Natural selection and mutability. Am. Nat. 104: 301.
33. Leigh, E. G., 1973 Evolution of mutation rates. Genetics 73: 1-18.
34. Lynch, M., 2008 The cellular, developmental and population-genetic determinants of mutation-rate evolution. Genetics 180: 933-943.
35. Mao, E. F., L. Lane, J. Lee, and J. H. Miller, 1997 Proliferation of mutators in a cell population. J. Bacteriol. 179: 417-422.
36. Matic, I., M. Radman, F. Taddei, B. Picard, C. Doit et al., 1997 Highly variable mutation rates in commensal and pathogenic Escherichia coli. Science 277: 1833-1834.
37. Notley-McRobb, L., S. Seeto, and T. Ferenci, 2002 Enrichment and elimination of muty mutators in Escherichia coli populations. Genetics 162: 1055-1062.
38. Oliver, A., R. Canton, P. Campo, F. Baquero, and J. Blazquez, 2000 High frequency of hypermutable Pseudomonas aerunginosa in cystic fibrosis lung infection. Science 288: 1251-1253.
39. Painter, P. R., 1975 Mutator genes and selection for the mutation rate in bacteria. Genetics 79: 649-660.
40. Pal, C., M. D. Macia, A. Oliver, I. Schachar, and A. Buckling, 2007 Coevolution with viruses drives the evolution of bacterial mutation rates. Nature 450: 1079-1081.
41. Peck, J. R., 1994 A ruby in the rubbish: beneficial mutations, deleterious mutations and the evolution of sex. Genetics 137: 597-606.
42. Prunier, A. L., B. Malbruny, M. Laurans, J. Brouard, J. F. Duhamel et al., 2003 High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains. J. Infect. Dis. 187: 1709-1716.
43. Richardson, A. R., Z. Yu, T. Popovic, and I. Stojiljkovic, 2002 Mutator clones of neisseria meningitidis in epidemic serogroup a disease. Proc. Natl. Acad. Sci. USA 99: 6103-6107.
44. Shaver, A. C., P. G. Dombrowski, J. Y. Sweeney, T. Treis, R. M. Zappala et al., 2002 Fitness evolution and the rise of mutator alleles in experimental Escherichia coli populations. Genetics 162: 557-566.
45. Sniegowski, P. D., P. J. Gerrish, and R. E. Lenski, 1997 Evolution of high mutation rates in experimental populations of E. coli. Nature 387: 703-705.
46. Soderberg, R. J., and O. G. Berg, 2011 Kick-starting the ratchet: the fate of mutators in asexual populations. Genetics 187: 1129-1137.
47. Taddei, F., M. Radman, J. Maynard-Smith, B. Toupance, and P. H. Gouyon et al., 1997 Role of mutator alleles in adaptive evolution. Nature 387: 700-702.
48. Tanaka, M. M., C. T. Bergstrom, and B. R. Levin, 2003 The evolution of mutator genes in bacterial populations: the roles of environmental change and timing. Genetics 164: 843-854.
49. Tenaillon, O., B. Toupance, H. Le Nagard, F. Taddei, and B. Godelle, 1999 Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria. Genetics 152: 485-493.
50. Tenaillon, O., H. Le Nagard, B. Godelle, and F. Taddei, 2000 Mutators and sex in bacteria: conflict between adaptive strategies. Proc. Natl. Acad. Sci. USA 97: 10465-10470.
51. Thompson, D. A., M. M. Desai, and A. W. Murray, 2006 Ploidy controls the success of mutators and nature of mutations during budding yeast evolution. Curr. Biol. 16: 1581-1590.
52. Travis, J., and E. Travis, 2002 Mutator dynamics in fluctuating environment. Proc. Biol. Sci. 269: 591-597.
53. Trobner, W., and R. Piechocki, 1981 Competition growth between Escherichia coli mutl and mut+ in continuously growing cultures. Z. Allg. Mikrobiol. 21: 347-349.
54. Watson, M. E., J. L. Burns, and A. L. Smith, 2004 Hypermutable haemophilus influenzae with mutations in muts are found in cystic fibrosis sputum. Microbiol. Sgm. 150: 2947-2958.
55. Wylie, C. S., C.-M. Ghim, D. Kessler, and H. Levine, 2009 The fixation probability of rare mutators in finite asexual populations. Genetics 181: 1595-1612.