메뉴 건너뛰기




Volumn 59, Issue 3, 2011, Pages 367-370

Stem cell therapy in stroke: Designing clinical trials

Author keywords

Clinical trial; Stem cell; Stroke

Indexed keywords

BIOLOGICAL MARKER;

EID: 80051508422     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.03.016     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 38049069788 scopus 로고    scopus 로고
    • Neurol stem/precursor cells for the treatment of ischemic stroke
    • M. Bacigaluppi, S. Pluchino, and G. Martino Neurol stem/precursor cells for the treatment of ischemic stroke J. Neurol. Sci. 265 2008 73 77
    • (2008) J. Neurol. Sci. , vol.265 , pp. 73-77
    • Bacigaluppi, M.1    Pluchino, S.2    Martino, G.3
  • 2
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • DOI 10.1002/ana.20501
    • Y.O. Bang, J.S. Lee, and P.H. Lee Autologous mesenchymal stem cell transplantation in stroke patients Ann. Neurol. 57 2005 874 882 (Pubitemid 40798626)
    • (2005) Annals of Neurology , vol.57 , Issue.6 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 3
    • 4644355953 scopus 로고    scopus 로고
    • Neuroimaging in stroke recovery: A position paper from the First International workshop on neuroimaging and stroke recovery
    • J. Baron, L. Cohen, and S. Cramer Neuroimaging in stroke recovery: a position paper from the First International workshop on neuroimaging and stroke recovery Cerebrovasc. Dis. 18 2004 260 267
    • (2004) Cerebrovasc. Dis. , vol.18 , pp. 260-267
    • Baron, J.1    Cohen, L.2    Cramer, S.3
  • 4
    • 33645231127 scopus 로고    scopus 로고
    • Chemokines regulate the migration of neural progenitors to sites of neuroinflammation
    • A. Belmadani, P.B. Tran, and D. Ren Chemokines regulate the migration of neural progenitors to sites of neuroinflammation J. Neurosci. 26 12 2006 3182 3191
    • (2006) J. Neurosci. , vol.26 , Issue.12 , pp. 3182-3191
    • Belmadani, A.1    Tran, P.B.2    Ren, D.3
  • 5
    • 33645860187 scopus 로고    scopus 로고
    • Transplantation of hNT neurons into the ischemic cortex: Cell survival and effect on sensorimotor behavior
    • T.M. Bliss, S. Kelly, and A.K. Shah Transplantation of hNT neurons into the ischemic cortex: cell survival and effect on sensorimotor behavior J. Neurosci. Res. 83 2006 1004 1014
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1004-1014
    • Bliss, T.M.1    Kelly, S.2    Shah, A.K.3
  • 6
    • 0032006347 scopus 로고    scopus 로고
    • Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats
    • DOI 10.1006/exnr.1997.6730
    • C.V. Borlongan, Y. Tajima, and J.Q. Trojanowski Transplantation of cryopreserved human embryonal-carcinoma-derived neuros (NT2N) promotes functional recovery in ischemic rats Exp. Neurol. 149 1998 310 321 (Pubitemid 28115069)
    • (1998) Experimental Neurology , vol.149 , Issue.2 , pp. 310-321
    • Borlongan, C.V.1    Tajima, Y.2    Trojanowski, J.Q.3    Lee, V.M.-Y.4    Sanberg, P.R.5
  • 7
    • 48849113339 scopus 로고    scopus 로고
    • Potential of stem/progenitor cells in treating stroke: The missing steps in translating cell therapy from laboratory to clinic
    • C.V. Borlongan, M. Chopp, and G.K. Steinberg Potential of stem/progenitor cells in treating stroke: the missing steps in translating cell therapy from laboratory to clinic Regen. Med. 3 2008 249 250
    • (2008) Regen. Med. , vol.3 , pp. 249-250
    • Borlongan, C.V.1    Chopp, M.2    Steinberg, G.K.3
  • 8
    • 0033603794 scopus 로고    scopus 로고
    • Users' guides to the medical literature: XIX. Applying clinical trial results A. How to use an article measuring the effect of an intervention on surrogate end points
    • DOI 10.1001/jama.282.8.771
    • H. Butcher, G. Guyatt, and D. Cook Users' guide to the medical literature. XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points. Evidence-Based Medicine working Group JAMA 282 1999 771 778 (Pubitemid 29404385)
    • (1999) Journal of the American Medical Association , vol.282 , Issue.8 , pp. 771-778
    • Bucher, H.C.1    Guyatt, G.H.2    Cook, D.J.3    Holbrook, A.4    McAlister, F.A.5
  • 10
    • 0035881367 scopus 로고    scopus 로고
    • Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats
    • DOI 10.1016/S0022-510X(01)00557-3, PII S0022510X01005573
    • J. Chen, Y. Li, and L. Wang Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats J. Neurol. Sci. 189 12 2001 49 57 (Pubitemid 32776649)
    • (2001) Journal of the Neurological Sciences , vol.189 , Issue.1-2 , pp. 49-57
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Zhang, X.5    Chopp, M.6
  • 11
    • 0037418936 scopus 로고    scopus 로고
    • Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
    • DOI 10.1161/01.RES.0000063425.51108.8D
    • J. Chen, Z.G. Zhang, and Y. Li Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats Circ. Res. 92 6 2003 692 699 (Pubitemid 36417705)
    • (2003) Circulation Research , vol.92 , Issue.6 , pp. 692-699
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3    Wang, L.4    Xu, Y.X.5    Gautam, S.C.6    Lu, M.7    Zhu, Z.8    Chopp, M.9
  • 14
    • 0041885413 scopus 로고    scopus 로고
    • Functional imaging in phase I studies: Decorations or decision making?
    • DOI 10.1200/JCO.2003.05.100
    • J.M. Collins Functional imaging in Phase I studies: decorations or decision making? J. Clin. Oncol. 21 2003 2807 2809 (Pubitemid 46621827)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.15 , pp. 2807-2809
    • Collins, J.M.1
  • 15
    • 34247869881 scopus 로고    scopus 로고
    • The case for modality-specific outcome measures in clinical trials of stroke recovery-promoting agents
    • DOI 10.1161/01.STR.0000260087.67462.80
    • S.C. Cramer, W.J. Koroshetz, and S.P. Finklestein The case for modality-specific outcome measures in clinical trials of stroke recovery-promoting agents Stroke 38 4 2007 1393 1395 (Pubitemid 351664265)
    • (2007) Stroke , vol.38 , Issue.4 , pp. 1393-1395
    • Cramer, S.C.1    Koroshetz, W.J.2    Finklestein, S.P.3
  • 16
    • 34547630679 scopus 로고    scopus 로고
    • Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum
    • DOI 10.1111/j.1460-9568.2007.05702.x
    • V. Darsalia, T. Kallu, and Z. Kokaia Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-dam,aged rat striatum Eur. J. Neurosci. 26 2007 605 614 (Pubitemid 47206801)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.3 , pp. 605-614
    • Darsalia, V.1    Kallur, T.2    Kokaia, Z.3
  • 17
    • 52449093262 scopus 로고    scopus 로고
    • The placebo treatments in neurosciences: New insights from clinical and neuroimaging studies
    • N.J. Diederich, and C.G. Goetz The placebo treatments in neurosciences: new insights from clinical and neuroimaging studies Neurology 71 2008 677 684
    • (2008) Neurology , vol.71 , pp. 677-684
    • Diederich, N.J.1    Goetz, C.G.2
  • 18
    • 0030268577 scopus 로고    scopus 로고
    • Surrogate End Points in Clinical Trials: Are We Being Misled?
    • T. Fleming, and D DeMets Surrogate end points in clinical trials: are we being misled? Ann. Intern. Med. 125 1996 605 613 (Pubitemid 126450094)
    • (1996) Annals of Internal Medicine , vol.125 , Issue.7 , pp. 605-613
    • Fleming, T.R.1    DeMets, D.L.2
  • 20
    • 59149083670 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: Cell survival and functional recovery
    • A.U. Hicks, R.S. Lappalainen, and S. Narkilahti Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery Eur. J. Neurosci. 29 2009 562 574
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 562-574
    • Hicks, A.U.1    Lappalainen, R.S.2    Narkilahti, S.3
  • 22
    • 0024852022 scopus 로고
    • Measurement of health status. Ascertaining the minimal clinically important difference
    • DOI 10.1016/0197-2456(89)90005-6
    • R. Jaeshke, J. Singer, and G.H. Guyatt Measurement of health status: ascertaining the minimal clinically important difference Controll. Clin. Trials 10 1989 407 415 (Pubitemid 20025670)
    • (1989) Controlled Clinical Trials , vol.10 , Issue.4 , pp. 407-415
    • Jaeschke, R.1    Singer, J.2    Guyatt, G.H.3
  • 23
    • 33747806913 scopus 로고    scopus 로고
    • MRI detects white matter reorganization after neural progenitor cell treatment of stroke
    • Q. Jiang, Z.G. Zhang, and G.L. Ding MRI detects white matter reorganization after neural progenitor cell treatment of stroke Neuroimage 32 2006 215 223
    • (2006) Neuroimage , vol.32 , pp. 215-223
    • Jiang, Q.1    Zhang, Z.G.2    Ding, G.L.3
  • 24
    • 33744973270 scopus 로고    scopus 로고
    • Clinical interpretation and use of stroke scales
    • DOI 10.1016/S1474-4422(06)70495-1, PII S1474442206704951
    • S.E. Kasner Clinical interpretation and use of stroke scales Lancet Neurol. 5 2006 603 612 (Pubitemid 43867434)
    • (2006) Lancet Neurology , vol.5 , Issue.7 , pp. 603-612
    • Kasner, S.E.1
  • 26
    • 34548569964 scopus 로고    scopus 로고
    • Systematic assessment of training induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation
    • J. Kleim, E. Kleim, and S. Cramer Systematic assessment of training induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation Nat. Protoc. 2 2007 1675 1684
    • (2007) Nat. Protoc. , vol.2 , pp. 1675-1684
    • Kleim, J.1    Kleim, E.2    Cramer, S.3
  • 28
    • 0035954362 scopus 로고    scopus 로고
    • Treatment of stroke in rat with intracarotid administration of marrow stromal cells
    • Y. Li, J. Chen, and L Wang Treatment of stroke in rat with intracarotid administration of marrow stromal cells Neurology 56 12 2001 1666 1672 (Pubitemid 32574564)
    • (2001) Neurology , vol.56 , Issue.12 , pp. 1666-1672
    • Li, Y.1    Chen, J.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 29
    • 0033844402 scopus 로고    scopus 로고
    • Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice
    • Y. Li, M. Chopp, and J. Chen Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice J. Cereb Blood Flow Metab. 20 9 2000 1311 1319
    • (2000) J. Cereb Blood Flow Metab. , vol.20 , Issue.9 , pp. 1311-1319
    • Li, Y.1    Chopp, M.2    Chen, J.3
  • 31
    • 33751159405 scopus 로고    scopus 로고
    • Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats
    • S. Makinen, T. Kekarainen, and J. Nystedt Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats Brain Res. 1123 1 2006 207 215
    • (2006) Brain Res. , vol.1123 , Issue.1 , pp. 207-215
    • Makinen, S.1    Kekarainen, T.2    Nystedt, J.3
  • 32
    • 0036715222 scopus 로고    scopus 로고
    • Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
    • DOI 10.1161/01.STR.0000027693.50675.C5
    • M. Modo, R.P. Stroemer, and E. Tang Effects of implantation site of stem cell grafts on behavioural recovery from stroke damage Stroke 33 2002 2270 2278 (Pubitemid 35014642)
    • (2002) Stroke , vol.33 , Issue.9 , pp. 2270-2278
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Patel, S.4    Hodges, H.5
  • 33
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute Of Neurological Disorders And Stroke Rt-Pa Stroke Study Group
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group Tissue plasminogen activator for acute ischemic stroke N. Engl. J. Med. 333 1995 1581 1587
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1581-1587
  • 36
    • 0345827419 scopus 로고    scopus 로고
    • Basal Forebrain Cholinergic System Is Involved in Rapid Nerve Growth Factor (NGF)-Induced Plasticity in the Barrel Cortex of Adult Rats
    • DOI 10.1152/jn.00489.2003
    • N. Prakash, S. Cohen-Cory, and S. Penschuck Basal forebrain cholinergic system is involved in rapid nerve growth factor (NGF)-induced plasticity in the barrel cortex of adult rats J. Neurophysiol. 91 2004 424 437 (Pubitemid 38084385)
    • (2004) Journal of Neurophysiology , vol.91 , Issue.1 , pp. 424-437
    • Prakash, N.1    Cohen-Cory, S.2    Penschuck, S.3    Frostig, R.D.4
  • 38
    • 23844487540 scopus 로고    scopus 로고
    • Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: A preliminary safety and feasibility study
    • DOI 10.1159/000086518
    • S.I. Savitz, J. Dinsmore, and J. Wu Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study Cerebrovasc. Dis. 20 2005 101 107 (Pubitemid 41160209)
    • (2005) Cerebrovascular Diseases , vol.20 , Issue.2 , pp. 101-107
    • Savitz, S.I.1    Dinsmore, J.2    Wu, J.3    Henderson, G.V.4    Stieg, P.5    Caplan, L.R.6
  • 39
    • 33748591618 scopus 로고    scopus 로고
    • A standardized motor threshold estimation procedure for transcranial magnetic stimulation research
    • DOI 10.1097/01.yct.0000235924.60364.27, PII 0012450920060900000004
    • D.J. Schutter, and J. van Honk A standardized motor threshold estimation procedure for transcranial magnetic stimulation research J. ECT 22 2006 176 178 (Pubitemid 44379371)
    • (2006) Journal of ECT , vol.22 , Issue.3 , pp. 176-178
    • Schutter, D.J.L.G.1    Van Honk, J.2
  • 41
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • STAIR Members Recommendations for standards regarding preclinical neuroprotective and restorative drug development Stroke 30 1999 2752 2758
    • (1999) Stroke , vol.30 , pp. 2752-2758
    • Members, S.1
  • 42
    • 60549090781 scopus 로고    scopus 로고
    • Stem cell therapies as an emerging paradigm in stroke (STEPS)
    • STEPS Participants Stem cell therapies as an emerging paradigm in stroke (STEPS) Stroke 40 2009 510 515
    • (2009) Stroke , vol.40 , pp. 510-515
    • Participants, S.1
  • 43
    • 44949166540 scopus 로고    scopus 로고
    • Organised inpatient (stroke unit) care for stroke
    • Stroke Unit Trialists' Collaboration CD000197
    • Stroke Unit Trialists' Collaboration Organised inpatient (stroke unit) care for stroke Cochrane Database Syst Rev. 4 2007 CD000197
    • (2007) Cochrane Database Syst Rev. , vol.4
  • 45
    • 0023103459 scopus 로고
    • Functional abilities after stroke: Measurement, natural history and prognosis
    • D.T. Wade, and RL Hewer Functional abilities after stroke: measurement, natural history and prognosis J. Neuro. Neurosurg. Psychiatry 50 1987 177 182 (Pubitemid 17016558)
    • (1987) Journal of Neurology Neurosurgery and Psychiatry , vol.50 , Issue.2 , pp. 177-182
    • Wade, D.T.1    Hewer, R.L.2
  • 47
    • 33746001384 scopus 로고    scopus 로고
    • Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats
    • DOI 10.1016/j.neuroscience.2006.04.054, PII S0306452206004982
    • C. Zhang, Y. Li, and J. Chen Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4 gap junction protein connexion-43 and synaptophysin after stroke in rats Neuroscience 141 2 2006 687 695 (Pubitemid 44066656)
    • (2006) Neuroscience , vol.141 , Issue.2 , pp. 687-695
    • Zhang, C.1    Li, Y.2    Chen, J.3    Gao, Q.4    Zacharek, A.5    Kapke, A.6    Chopp, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.