Interleukin-17A is involved in development of spontaneous pulmonary emphysema caused by Toll-like receptor 4 mutation

Acta Pharmacologica Sinica

Volumn 32, Issue 8, 2011, Pages 1045-1054

  Wang, Qing Qing ^a   Yang, Hong Zhen ^a   Liu, Han Zhi ^a   Mi, Su ^a   Zhang, Xiao Wei ^a   Yan, Hui Min ^a   Ma, Yong Gang ^a   Wang, Xiao Xing ^a   Hu, Zhuo Wei ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

emphysema; IL 17A; Th17 cells; Toll like receptor 4

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL POLARITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE MUTATION; HISTOPATHOLOGY; IMMUNOCHEMISTRY; IMMUNOPATHOGENESIS; LUNG EMPHYSEMA; LUNG LAVAGE; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TH17 CELL; WESTERN BLOTTING; WILD TYPE;

ANIMALS; INTERLEUKIN-17; MICE; MICE, INBRED C3H; MUTATION; PULMONARY EMPHYSEMA; TH17 CELLS; TOLL-LIKE RECEPTOR 4;

EID: 80051479905     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.67     Document Type: Article

References (39)

1. Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev 2007; 87: 1047-82. (Pubitemid 47084676)
2. Taraseviciene-Stewart L, Voelkel NF. Molecular pathogenesis of emphysema. J Clin Invest 2008; 118: 394-402.
3. Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, et al. Percent emphysema, airflow obstruction, and impaired left ventricular filling. N Engl J Med 2010; 362: 217-27.
4. Boutten A, Goven D, Boczkowski J, Bonay M. Oxidative stress targets in pulmonary emphysema: Focus on the Nrf2 pathway. Expert Opin Ther Targets 2010; 14: 329-46.
5. Horowitz JC, Martinez FJ, Thannickal VJ. Mesenchymal cell fate and phenotypes in the pathogenesis of emphysema. COPD 2009; 6: 201-10.
6. Calverley PM, Rennard SI. What have we learned from large drug treatment trials in COPD? Lancet 2007; 370: 774-85. (Pubitemid 47320801)
7. Zhang X, Shan P, Jiang G, Cohn L, Lee PJ. Toll-like receptor 4 deficiency causes pulmonary emphysema. J Clin Invest 2006; 116: 3050-9. (Pubitemid 44684490)
8. Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med 2007; 13: 567-9. (Pubitemid 46828488)
9. Vercelli D. Gene-environment interactions in asthma and allergy: The end of the beginning? Curr Opin Allergy Clin Immunol 2010; 10: 145-8.
10. Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007; 148: 32-46. (Pubitemid 46365005)
11. Gill R, Tsung A, Billiar T. Linking oxidative stress to inflammation: Tolllike receptors. Free Radic Biol Med 2010; 48: 1121-32.
12. Won HY, Sohn JH, Min HJ, Lee K, Woo HA, Ho YS, et al. Glutathione peroxidase 1 deficiency attenuates allergen-induced airway inflammation by suppressing Th2 and Th17 cell development. Antioxid Redox Signal 2010; 13: 575-87.
13. Inoue D, Numasaki M, Watanabe M, Kubo H, Sasaki T, Yasuda H, et al. IL-17A promotes the growth of airway epithelial cells through ERK- dependent signaling pathway. Biochem Biophys Res Commun 2006; 347: 852-8. (Pubitemid 44118197)
14. Kawakami M, Matsuo Y, Yoshiura K, Nagase T, Yamashita N. Sequential and quantitative analysis of a murine model of elastase-induced emphysema. Biol Pharm Bull 2008; 31: 1434-8. (Pubitemid 351930664)
15. D'Hulst AI, Vermaelen KY, Brusselle GG, Joos GF, Pauwels RA. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J 2005; 26: 204-13 (Pubitemid 41079063)
16. Zha RP, Xu W, Wang WY, Dong L, Wang YP. Prevention of lipopolysaccharide- induced injury by 3,5-dicaffeoylquinic acid in endothelial cells. Acta Pharmacol Sin 2007; 28: 1143-8. (Pubitemid 47197771)
17. Traidl-Hoffmann C, Mariani V, Hochrein H, Karg K, Wagner H, Ring J, et al. Pollen-associated phytoprostanes inhibit dendritic cell interleukin- production and augment T helper type 2 cell polarization. J Exp Med 2005; 201: 627-36.
18. Yang HZ, Cui B, Liu HZ, Chen ZR, Yan HM, Hua F, et al. Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironment. J Immunol 2009; 182: 692-702.
19. Jakob T, Walker PS, Krieg AM, Udey MC, Vogel JC. Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J Immunol 1998; 161: 3042-9. (Pubitemid 28425730)
20. Cai WF, Zhang XW, Yan HM, Ma YG, Wang XX, Yan J, et al. Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice. Cardiovasc Res 2010; 88: 140-9.
21. Amati L, Pepe M, Passeri ME, Mastronardi ML, Jirillo E, Covelli V. Tolllike receptor signaling mechanisms involved in dendritic cell activation: Potential therapeutic control of T cell polarization. Curr Pharm Des 2006; 12: 4247-54. (Pubitemid 44669752)
22. Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 cells. AnnuRev Immunol 2009; 27: 485-517.
23. Gaffen SL. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 2009; 9: 556-67.
24. Hong SC, Lee SH. Role of Th17 cell and autoimmunity in chronic obstructive pulmonary disease. Immune Netw 2010; 10: 109-14.
25. McKenzie BS, Kastelein RA, Cua DJ. Understanding the IL-23 - IL-17 immune pathway. Trends Immunol 2006; 27: 17-23. (Pubitemid 43083560)
26. Kishimoto T. Interleukin-6: From basic science to medicine - 40 years in immunology. Annu Rev Immunol 2005; 23: 1-21. (Pubitemid 40563163)
27. Mudter J, Yu J, Zufferey C, Br?stle A, Wirtz S, Weigmann B, et al. IRF4 regulates IL-17A promoter activity and controls ROR?t-dependent Th17 colitis in vivo. Inflamm Bowel Dis 2011; 17: 1343-58.
28. Duarte PM, Santos VR, Dos Santos FA, de Lima Pereira SA, Rodrigues DB, Napimoga MH. Role of smoking and type 2 diabetes in the immunobalance of advanced chronic periodontitis. J Periodontol 2011; 82: 429-38.
29. Yoshizaki A, Yanaba K, Iwata Y, Komura K, Ogawa A, Akiyama Y, et al. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J Immunol 2010; 185: 2502-15.
30. Harrison OJ, Foley J, Bolognese BJ, Long E 3rd, Podolin PL, Walsh PT. Airway infiltration of CD4+ CCR6+ Th17 type cells associated with chronic cigarette smoke induced airspace enlargement. Immunol Lett 2008; 121: 13-21.
31. Lane N, Robins RA, Corne J, Fairclough L. Regulation in chronic obstructive pulmonary disease: The role of regulatory T-cells and Th17 cells. Clin Sci (Lond) 2010; 119: 75-86.
32. Melgert BN, Timens W, Kerstjens HA, Geerlings M, Luinge MA, Schouten JP, et al. Effects of 4 months of smoking in mice with ovalbumin-induced airway inflammation. Clin Exp Allergy 2007; 37: 1798-808. (Pubitemid 350145340)
33. Tang H, Pang S, Wang M, Xiao X, Rong Y, Wang H, et al. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol 2010; 185: 2563-9.
34. Loser K, Vogl T, Voskort M, Lueken A, Kupas V, Nacken W, et al. The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells. Nat Med 2010; 16: 713-7.
35. Mu HH, Hasebe A, Van Schelt A, Cole BC. Novel interactions of a microbial superantigen with TLR2 and TLR4 differentially regulate IL- 17 and Th17-associated cytokines. Cell Microbiol 2011; 13: 374-87.
36. Bhan U, Ballinger MN, Zeng X, Newstead MJ, Cornicelli MD, Standiford TJ. Cooperative interactions between TLR4 and TLR9 regulate interleukin 23 and 17 production in a murine model of gram negative bacterial pneumonia. PLoS One 2010; 5: E9896.
37. van de Veerdonk FL, Teirlinck AC, Kleinnijenhuis J, Kullberg BJ, van Crevel R, van der Meer JW, et al. Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1. J Leukoc Biol 2010; 88: 227-32.
38. Banus S, Stenger RM, Gremmer ER, Dormans JA, Mooi FR, Kimman TG, et al. The role of Toll-like receptor-4 in pertussis vaccine-induced immunity. BMC Immunol 2008; 9: 21.
39. Wenink MH, Santegoets KC, Broen JC, van Bon L, Abdollahi-Roodsaz S, Popa C, et al. TLR2 promotes Th2/Th17 responses via TLR4 and TLR7/8 by abrogating the type I IFN amplification loop. J Immunol 2009; 183: 6960-70.