Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

Developmental Biology

Volumn 357, Issue 1, 2011, Pages 227-234

  Plageman, Timothy F ^a   Zacharias, Amanda L ^c   Gage, Phillip J ^c   Lang, Richard A ^a,b  

^a Molecular Immunology   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; F ACTIN; MYOSIN II; NERVE CELL ADHESION MOLECULE; SHROOM 3 PROTEIN; TRANSCRIPTION FACTOR PITX2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CELL SHAPE; CONTROLLED STUDY; EMBRYO; EPITHELIUM; GENE INTERACTION; HETEROZYGOSITY; INTESTINE; MESENTERY; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

EID: 80051473676     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2011.06.027     Document Type: Article

References (33)

1. Ai D., Liu W., Ma L., Dong F., Lu M.F., Wang D., Verzi M.P., Cai C., Gage P.J., Evans S., et al. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev. Biol. 2006, 296(2):437-449.
2. Campione M., Steinbeisser H., Schweickert A., Deissler K., van Bebber F., Lowe L.A., Nowotschin S., Viebahn C., Haffter P., Kuehn M.R., et al. The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. Development 1999, 126(6):1225-1234.
3. Chung M.I., Nascone-Yoder N.M., Grover S.A., Drysdale T.A., Wallingford J.B. Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut. Development 2010, 137(8):1339-1349.
4. Davis N.M., Kurpios N.A., Sun X., Gros J., Martin J.F., Tabin C.J. The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery. Dev. Cell 2008, 15(1):134-145.
5. Gage P.J., Suh H., Camper S.A. Dosage requirement of Pitx2 for development of multiple organs. Development 1999, 126(20):4643-4651.
6. Haigo S.L., Hildebrand J.D., Harland R.M., Wallingford J.B. Shroom induces apical constriction and is required for hingepoint formation during neural tube closure. Curr. Biol. 2003, 13(24):2125-2137.
7. Hardin J., Keller R. The behaviour and function of bottle cells during gastrulation of Xenopus laevis. Development 1988, 103(1):211-230.
8. Hildebrand J.D. Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network. J. Cell Sci. 2005, 118(Pt 22):5191-5203.
9. Hildebrand J.D., Soriano P. Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell 1999, 99(5):485-497.
10. Kostetskii I., Li J., Xiong Y., Zhou R., Ferrari V.A., Patel V.V., Molkentin J.D., Radice G.L. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ. Res. 2005, 96(3):346-354.
11. Kurpios N.A., Ibanes M., Davis N.M., Lui W., Katz T., Martin J.F., Izpisua Belmonte J.C., Tabin C.J. The direction of gut looping is established by changes in the extracellular matrix and in cell:cell adhesion. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(25):8499-8506.
12. Lee C., Scherr H.M., Wallingford J.B. Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change. Development 2007, 134(7):1431-1441.
13. Lee C., Le M.P., Wallingford J.B. The shroom family proteins play broad roles in the morphogenesis of thickened epithelial sheets. Dev. Dyn. 2009, 238(6):1480-1491.
14. Leonard M., Zhang L., Zhai N., Cader A., Chan Y., Nowak R.B., Fowler V.M., Menko A.S. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens 2010, Dev Biol.
15. Leptin M., Grunewald B. Cell shape changes during gastrulation in Drosophila. Development 1990, 110(1):73-84.
16. Lin C.R., Kioussi C., O'Connell S., Briata P., Szeto D., Liu F., Izpisua-Belmonte J.C., Rosenfeld M.G. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature 1999, 401(6750):279-282.
17. Liu C., Liu W., Lu M.F., Brown N.A., Martin J.F. Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development 2001, 128(11):2039-2048.
18. Logan M., Pagan-Westphal S.M., Smith D.M., Paganessi L., Tabin C.J. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell 1998, 94(3):307-317.
19. Lu M.F., Pressman C., Dyer R., Johnson R.L., Martin J.F. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 1999, 401(6750):276-278.
20. Morita H., Nandadasa S., Yamamoto T.S., Terasaka-Iioka C., Wylie C., Ueno N. Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Development 2010, 137(8):1315-1325.
21. Nandadasa S., Tao Q., Menon N.R., Heasman J., Wylie C. N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements. Development 2009, 136(8):1327-1338.
22. Nishimura T., Takeichi M. Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling. Development 2008, 135(8):1493-1502.
23. Novak A., Guo C., Yang W., Nagy A., Lobe C.G. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 2000, 28(3-4):147-155.
24. Pilot F., Lecuit T. Compartmentalized morphogenesis in epithelia: from cell to tissue shape. Dev. Dyn. 2005, 232(3):685-694.
25. Plageman T.F., Chung M.I., Lou M., Smith A.N., Hildebrand J.D., Wallingford J.B., Lang R.A. Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination. Development 2010, 137(3):405-415.
26. Pontoriero G.F., Smith A.N., Miller L.A., Radice G.L., West-Mays J.A., Lang R.A. Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev. Biol. 2009, 326(2):403-417.
27. Radice G.L., Rayburn H., Matsunami H., Knudsen K.A., Takeichi M., Hynes R.O. Developmental defects in mouse embryos lacking N-cadherin. Dev. Biol. 1997, 181(1):64-78.
28. Ryan A.K., Blumberg B., Rodriguez-Esteban C., Yonei-Tamura S., Tamura K., Tsukui T., de la Pena J., Sabbagh W., Greenwald J., Choe S., et al. Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature 1998, 394(6693):545-551.
29. Sawyer J.K., Harris N.J., Slep K.C., Gaul U., Peifer M. The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J. Cell Biol. 2009, 186(1):57-73.
30. Shiratori H., Sakuma R., Watanabe M., Hashiguchi H., Mochida K., Sakai Y., Nishino J., Saijoh Y., Whitman M., Hamada H. Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. Mol. Cell 2001, 7(1):137-149.
31. Shiratori H., Yashiro K., Shen M.M., Hamada H. Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs. Development 2006, 133(15):3015-3025.
32. Smith A.N., Miller L.A., Song N., Taketo M.M., Lang R.A. The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev. Biol. 2005, 285(2):477-489.
33. Yoshioka H., Meno C., Koshiba K., Sugihara M., Itoh H., Ishimaru Y., Inoue T., Ohuchi H., Semina E.V., Murray J.C., et al. Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell 1998, 94(3):299-305.