Recombinant hBMP4 incorporated with non-canonical amino acid for binding to hydroxyapatite

Biotechnology Letters

Volumn 33, Issue 9, 2011, Pages 1885-1890

  Sakuragi, Makoto ^a   Kitajima, Takashi ^a   Nagamune, Teruyuki ^b   Ito, Yoshihiro ^a  

^a RIKEN   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

BMP protein; Hydroxyapatite; Non canonical amino acid; Phosphorylated serine; Protein engineering; Sortase A; Statherin

Indexed keywords

BMP PROTEIN; NON-CANONICAL AMINO ACID; PHOSPHORYLATED SERINE; PROTEIN ENGINEERING; SORTASE; STATHERIN;

APATITE; BONE; GENETIC ENGINEERING; HYDROXYAPATITE; PEPTIDES; PHOSPHORYLATION;

AMINO ACIDS;

AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; BMP4 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 4; CYSTEINE PROTEINASE; HYDROXYAPATITE; RECOMBINANT PROTEIN; SERINE; SORTASE A;

ARTICLE; BONE DEVELOPMENT; CELL LINE; DRUG EFFECT; GENETICS; HUMAN; MESENCHYMAL STEM CELL; METABOLISM; PROTEIN BINDING;

AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; BONE MORPHOGENETIC PROTEIN 4; CELL LINE; CYSTEINE ENDOPEPTIDASES; DURAPATITE; HUMANS; MESENCHYMAL STEM CELLS; OSTEOGENESIS; PROTEIN BINDING; RECOMBINANT PROTEINS; SERINE;

EID: 80051472826     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-011-0637-1     Document Type: Article

References (21)

1. Chen D, Zhao M, Mundy GR (2004) Bone morphogenetic proteins. Growth Factors 22: 233-241.
2. Gilbert M, Shaw WJ, Long JR, Nelson K, Drobny GP, Giachelli CM, Stayton PS (2000) Chimeric peptides of statherin and osteopontin that bind hydroxyapatite and mediate cell adhesion. J Biol Chem 275: 16213-16218.
3. Hafiz Uddin M, Matsumoto T, Ishihara S, Nakahira A, Olazaki M, Sohmura T (2007) Modification of apatite materials for bone tissue engineering and drug delivery carriers. Curr Med Chem 14: 2726-2733.
4. Ito Y (2008) Covalently immobilized biosignal molecule materials for tissue engineering. Soft Matter 4: 46-56.
5. Ito Y (2009) Growth factors on biomaterial surfaces. In: Puleo DA, Bizios R (eds) Biological interactions on materials surfaces: understanding and controlling protein, cell and tissue responses. Springer, New York, pp 173-197.
6. Kamitakahara M, Ohtsuki C, Miyazaki T (2007) Coating of bone-like apatite for development of bioactive materials for bone reconstruction. Biomed Mater 2: R17-R23.
7. Kashiwagi K, Tsuji T, Shiba K (2009) Directional BMP-2 for functionalization of titanium surfaces. Biomaterials 30: 1166-1175.
8. Liu H, Webster TJ (2010) Ceramic/polymer nanocomposites with tunable drug delivery capability at specific disease sites. J Biomed Mater Res A 93: 1180-1192.
9. Mazmanian SK, Liu G, Ton-That H, Schneewind O (1999) Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science 285: 760-763.
10. Misra DN (1997) Interaction of ortho-phospho-l-serine with hydroxyapatite: formation of a surface complex. J Colloid Interface Sci 194: 249-255.
11. Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BL (1988) Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol 106: 441-450.
12. Parthasarathy R, Subramanian S, Boder ET (2007) Sortase A as a novel molecular "stapler" for sequence-specific protein conjugation. Bioconjugate Chem 18: 469-476.
13. Proft T (2009) Sortase-mediated protein ligation: an emerging biotechnology tool for protein modification and immobilisation. Biotechnol Lett 32: 1-10.
14. Raj PA, Johnsson M, Levine MJ, Nancollas GH (1992) Salivary statherin. Dependence on sequence, charge, hydrogen bonding potency, and helical conformation for adsorption to hydroxyapatite and inhibition of mineralization. J Biol Chem 267: 5968-5976.
15. Schuessele A, Mayr H, Tessmar J, Goepferich A (2009) Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces. J Biomed Mater Res A 90: 959-971.
16. Shaw WJ, Long JR, Dindot JL, Campbell AA, Stayton PS, Drobny GP (2000) Determination of statherin N-terminal peptide conformation on hydroxyapatite crystals. J Am Chem Soc 122: 1709-1716.
17. Tanaka T, Yamamoto T, Tsukiji S, Nagamune T (2008) Site-specific protein modification on living cells catalyzed by sortase. ChemBioChem 9: 802-807.
18. Taylor SM, Jones PA (1979) Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17: 771-779.
19. Yamaguchi A, Ishizuya T, Kintou N, Wada Y, Katagiri T, Wozney JM, Rosen V, Yoshiki S (1996) Effects of BMP-2, BMP4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem Biophys Res Commun 220: 366-371.
20. Yang Y, Cui Q, Sahai N (2010) How does bone sialoprotein promote the nucleation of hydroxyapatite? A molecular dynamics study using model peptides of different conformations. Langmuir 26: 9848-9859.
21. Yuasa T, Kataoka H, Kinto N, Iwamoto M, Enomoto-Iwamoto M, Ikemura S-I, Ueno N, Shibata Y, Kurosawa H, Yamaguchi A (2002) Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2. J Cell Physiol 193: 225-232.