메뉴 건너뛰기




Volumn 35, Issue 9, 2011, Pages 1164-1169

Dasatinib is safe and effective in unselected chronic myeloid leukaemia elderly patients resistant/intolerant to imatinib

(25)  Latagliata, Roberto a   Breccia, Massimo a   Castagnetti, Fausto b   Stagno, Fabio c   Luciano, Luigiana d   Gozzini, Antonella e   Ulisciani, Stefano f   Cavazzini, Francesco g   Annunziata, Mario h   Sorà, Federica i   Rossi, Antonella Russo j   Pregno, Patrizia k   Montefusco, Enrico l   Abruzzese, Elisabetta m   Crisà, Elena n   Musto, Pellegrino o   Tiribelli, Mario p   Binotto, Gianni q   Occhini, Ubaldo r   Feo, Costanzo s   more..


Author keywords

Chronic Myeloid Leukaemia; Dasatinib; Elderly; Safety

Indexed keywords

DASATINIB; IMATINIB;

EID: 80051471275     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.05.015     Document Type: Article
Times cited : (33)

References (19)
  • 2
    • 37249016890 scopus 로고    scopus 로고
    • BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria
    • Branford S., Seymour J., Grigg A., Arthur C., Rudzki Z., Lynch K., et al. BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria. Clin Cancer Res 2007, 13:7080-7086.
    • (2007) Clin Cancer Res , vol.13 , pp. 7080-7086
    • Branford, S.1    Seymour, J.2    Grigg, A.3    Arthur, C.4    Rudzki, Z.5    Lynch, K.6
  • 3
    • 38949178846 scopus 로고    scopus 로고
    • Favorable long-term follow-up results over six years for response, survival and safety with imatinib mesylate therapy in chronic phase chronic myeloid leukemia post failure of interferon-alpha treatment
    • Hochhaus A., Druker B., Sawyers C., Guilhot F., Schiffer C.A., Cortes J., et al. Favorable long-term follow-up results over six years for response, survival and safety with imatinib mesylate therapy in chronic phase chronic myeloid leukemia post failure of interferon-alpha treatment. Blood 2008, 111:1039-1043.
    • (2008) Blood , vol.111 , pp. 1039-1043
    • Hochhaus, A.1    Druker, B.2    Sawyers, C.3    Guilhot, F.4    Schiffer, C.A.5    Cortes, J.6
  • 4
    • 10744232328 scopus 로고    scopus 로고
    • Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
    • Branford S., Rudzki Z., Walsh S., Parkinson I., Grigg A., Szer J., et al. Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. Blood 2003, 102:276-283.
    • (2003) Blood , vol.102 , pp. 276-283
    • Branford, S.1    Rudzki, Z.2    Walsh, S.3    Parkinson, I.4    Grigg, A.5    Szer, J.6
  • 5
    • 37149012329 scopus 로고    scopus 로고
    • Strategies for overcoming imatinib resistance in chronic myeloid leukemia
    • Kujawski L., Talpaz M. Strategies for overcoming imatinib resistance in chronic myeloid leukemia. Leuk Lymph 2007, 48:2310-2322.
    • (2007) Leuk Lymph , vol.48 , pp. 2310-2322
    • Kujawski, L.1    Talpaz, M.2
  • 6
    • 21144451094 scopus 로고    scopus 로고
    • In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
    • O'Hare T., Walters D.K., Stoffregen E.P., Jia T., Manley P.W., Mestan J., et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res 2005, 65:4500-4505.
    • (2005) Cancer Res , vol.65 , pp. 4500-4505
    • O'Hare, T.1    Walters, D.K.2    Stoffregen, E.P.3    Jia, T.4    Manley, P.W.5    Mestan, J.6
  • 7
    • 33745283618 scopus 로고    scopus 로고
    • The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants
    • Tokarski J.S., Newitt J.A., Chang C.Y., Cheng J.D., Wittekind M., Kiefer S.E., et al. The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res 2006, 66:5790-5797.
    • (2006) Cancer Res , vol.66 , pp. 5790-5797
    • Tokarski, J.S.1    Newitt, J.A.2    Chang, C.Y.3    Cheng, J.D.4    Wittekind, M.5    Kiefer, S.E.6
  • 8
    • 33947280081 scopus 로고    scopus 로고
    • Dasatinib induces notable hematologic and cytogenetic responses in chronic phase chronic myeloid leukemia after failure of imatinib therapy
    • Hochhaus A., Kantarjian H.M., Baccarani M., Lipton J.H., Apperley J.F., Druker B.J., et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic phase chronic myeloid leukemia after failure of imatinib therapy. Blood 2007, 109:2303-2309.
    • (2007) Blood , vol.109 , pp. 2303-2309
    • Hochhaus, A.1    Kantarjian, H.M.2    Baccarani, M.3    Lipton, J.H.4    Apperley, J.F.5    Druker, B.J.6
  • 9
    • 45149087139 scopus 로고    scopus 로고
    • Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
    • Hochhaus A., Baccarani M., Deininger M., Apperley J.F., Lipton J.H., Goldberg S.L., et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib. Leukemia 2008, 22:1200-1206.
    • (2008) Leukemia , vol.22 , pp. 1200-1206
    • Hochhaus, A.1    Baccarani, M.2    Deininger, M.3    Apperley, J.F.4    Lipton, J.H.5    Goldberg, S.L.6
  • 10
    • 70149105272 scopus 로고    scopus 로고
    • Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized Phase 2 study (START-R)
    • Kantarjian H.M., Pasquini R., Levy V., Jootar S., Holowiecki J., Hamerschlak N., et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized Phase 2 study (START-R). Cancer 2009, 115:4136-4147.
    • (2009) Cancer , vol.115 , pp. 4136-4147
    • Kantarjian, H.M.1    Pasquini, R.2    Levy, V.3    Jootar, S.4    Holowiecki, J.5    Hamerschlak, N.6
  • 11
    • 76549116248 scopus 로고    scopus 로고
    • Potent, transient inhibition of BCR-ABL with dasatinib 100mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
    • Shah N.P., Kim D.W., Kantarjian H.M., Rousselot P., Llacer P.E., Enrico A., et al. Potent, transient inhibition of BCR-ABL with dasatinib 100mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica 2010, 95:232-240.
    • (2010) Haematologica , vol.95 , pp. 232-240
    • Shah, N.P.1    Kim, D.W.2    Kantarjian, H.M.3    Rousselot, P.4    Llacer, P.E.5    Enrico, A.6
  • 12
    • 0041917185 scopus 로고    scopus 로고
    • Effects of age on prognosis with imatinib mesylate therapy for patients with Philadelphia chromosome-positive chronic myelogenous leukemia
    • Cortes J., Talpaz M., O'Brien S., Giles F., Beth Rios M., Shan J., et al. Effects of age on prognosis with imatinib mesylate therapy for patients with Philadelphia chromosome-positive chronic myelogenous leukemia. Cancer 2003, 15(98:):1105-1113.
    • (2003) Cancer , vol.15 , Issue.98 , pp. 1105-1113
    • Cortes, J.1    Talpaz, M.2    O'Brien, S.3    Giles, F.4    Beth Rios, M.5    Shan, J.6
  • 13
    • 19944432935 scopus 로고    scopus 로고
    • Older patients with Ph+ chronic myelogenous leukemia (CML): results of imatinib mesylate treatment
    • Latagliata R., Breccia M., Carmosino I., Sarlo C., Montefusco E., Mancini M., et al. Older patients with Ph+ chronic myelogenous leukemia (CML): results of imatinib mesylate treatment. Leuk Res 2005, 29:287-291.
    • (2005) Leuk Res , vol.29 , pp. 287-291
    • Latagliata, R.1    Breccia, M.2    Carmosino, I.3    Sarlo, C.4    Montefusco, E.5    Mancini, M.6
  • 14
    • 33846935242 scopus 로고    scopus 로고
    • Impact of age on the outcome of patients with chronic myeloid leukemia in late chronic phase: results of a phase II study of the GIMEMA CML Working Party
    • Rosti G., Iacobucci I., Bassi S., Castagnetti F., Amabile M., Cilloni D., et al. Impact of age on the outcome of patients with chronic myeloid leukemia in late chronic phase: results of a phase II study of the GIMEMA CML Working Party. Haematologica 2007, 92:101-105.
    • (2007) Haematologica , vol.92 , pp. 101-105
    • Rosti, G.1    Iacobucci, I.2    Bassi, S.3    Castagnetti, F.4    Amabile, M.5    Cilloni, D.6
  • 15
    • 62549108246 scopus 로고    scopus 로고
    • Clinical trials underestimate the age of chronic myeloid leukemia (CML) patients. Incidence and median age of Ph/BCR-ABL-positive CML and other chronic myeloproliferative disorders in a representative area in Germany
    • Rohrbacher M., Berger U., Hochhaus A., Metzgeroth G., Adam K., Lahaye T., et al. Clinical trials underestimate the age of chronic myeloid leukemia (CML) patients. Incidence and median age of Ph/BCR-ABL-positive CML and other chronic myeloproliferative disorders in a representative area in Germany. Leukemia 2009, 23:602-604.
    • (2009) Leukemia , vol.23 , pp. 602-604
    • Rohrbacher, M.1    Berger, U.2    Hochhaus, A.3    Metzgeroth, G.4    Adam, K.5    Lahaye, T.6
  • 16
    • 33747154547 scopus 로고    scopus 로고
    • Evolving concepts in the management of chronic myeloid leukemia. Recommendations from an expert panel on behalf of the European Leukemianet
    • Baccarani M., Saglio G., Goldman J., Hochhaus A., Simonsson B., Appelbaum F., et al. Evolving concepts in the management of chronic myeloid leukemia. Recommendations from an expert panel on behalf of the European Leukemianet. Blood 2006, 108:1809-1818.
    • (2006) Blood , vol.108 , pp. 1809-1818
    • Baccarani, M.1    Saglio, G.2    Goldman, J.3    Hochhaus, A.4    Simonsson, B.5    Appelbaum, F.6
  • 17
    • 33745603988 scopus 로고    scopus 로고
    • Patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
    • Hughes T., Deininger M., Hochhaus A., Branford S., Radich J., Kaeda J., et al. patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood 2006, 108:28-37.
    • (2006) Blood , vol.108 , pp. 28-37
    • Hughes, T.1    Deininger, M.2    Hochhaus, A.3    Branford, S.4    Radich, J.5    Kaeda, J.6
  • 18
    • 54049139246 scopus 로고    scopus 로고
    • Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials
    • Branford S., Fletcher L., Cross N.C., Muller M.C., Hochhaus A., Kim D.W., et al. Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials. Blood 2008, 112:3330-3338.
    • (2008) Blood , vol.112 , pp. 3330-3338
    • Branford, S.1    Fletcher, L.2    Cross, N.C.3    Muller, M.C.4    Hochhaus, A.5    Kim, D.W.6
  • 19
    • 38349081290 scopus 로고    scopus 로고
    • Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories
    • Muller M.C., Erben P., Saglio G., Gottardi E., Nyvold C.G., Schenk T., et al. Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories. Leukemia 2008, 22:96-102.
    • (2008) Leukemia , vol.22 , pp. 96-102
    • Muller, M.C.1    Erben, P.2    Saglio, G.3    Gottardi, E.4    Nyvold, C.G.5    Schenk, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.