Role of self-medication in the development of comorbid anxiety and substance use disorders: A longitudinal investigation

Archives of General Psychiatry

Volumn 68, Issue 8, 2011, Pages 800-807

  Robinson, Jennifer ^a   Sareen, Jitender ^a   Cox, Brian J ^a   Bolton, James M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANXIETY DISORDER; ARTICLE; COMORBIDITY; CONTROLLED STUDY; DEMOGRAPHY; EDUCATIONAL STATUS; ETHNICITY; FEMALE; HEALTH SURVEY; HUMAN; INCOME; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MARRIAGE; NATIONAL HEALTH ORGANIZATION; RACE; RISK FACTOR; SELF MEDICATION; SOCIAL ASPECT; SOCIAL PHOBIA; STATISTICAL ANALYSIS; SUBSTANCE ABUSE; UNITED STATES; URBAN POPULATION;

ADOLESCENT; ADULT; AGED; ANXIETY; DIAGNOSIS, DUAL (PSYCHIATRY); FEMALE; HEALTH SURVEYS; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; RISK FACTORS; SELF MEDICATION; SUBSTANCE-RELATED DISORDERS;

EID: 79961215800     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archgenpsychiatry.2011.75     Document Type: Article

References (51)

1. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiatry. 1994;51(1):8-19. (Pubitemid 24028993)
2. Roy-Byrne PP, Stang P, Wittchen HU, Ustun B, Walters EE, Kessler RC. Lifetime panic-depression comorbidity in the National Comorbidity Survey: association with symptoms, impairment, course and help-seeking. Br J Psychiatry. 2000; 176:229-235. (Pubitemid 30179841)
3. Bijl RV, Ravelli A. Psychiatric morbidity, service use, and need for care in the general population: results of The Netherlands Mental Health Survey and Incidence Study. Am J Public Health. 2000;90(4):602-607. (Pubitemid 30167422)
4. Merikangas KR, Zhang H, Avenevoli S, Acharyya S, Neuenschwander M, Angst J; Zurich Cohort Study. Longitudinal trajectories of depression and anxiety in a prospective community study: the Zurich Cohort Study. Arch Gen Psychiatry. 2003;60(10):993-1000. (Pubitemid 37222082)
5. Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication [published correction appears in Arch Gen Psychiatry. 2005;62(7):709]. Arch Gen Psychiatry. 2005;62(6):617-627.
6. Bibb JL, Chambless DL. Alcohol use and abuse among diagnosed agoraphobics. Behav Res Ther. 1986;24(1):49-58.
7. de Graaf R, Bijl RV, Smit F, Vollebergh WA, Spijker J. Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study. Am J Psychiatry. 2002; 159(4):620-629.
8. Sareen J, McWilliams L, Cox B, Stein MB. Does a U-shaped relationship exist between alcohol use and DSM-III-R mood and anxiety disorders? J Affect Disord. 2004;82(1):113-118. (Pubitemid 39311974)
9. Swendsen JD, Merikangas KR, Canino GJ, Kessler RC, Rubio-Stipec M, Angst J. The comorbidity of alcoholism with anxiety and depressive disorders in four geographic communities. Compr Psychiatry. 1998;39(4):176-184. (Pubitemid 28326189)
10. Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, Pickering RP, Kaplan K. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry. 2004;61(8): 807-816. (Pubitemid 39031120)
11. Mullaney JA, Trippett CJ. Alcohol dependence and phobias: clinical description and relevance. Br J Psychiatry. 1979;135:565-573. (Pubitemid 10214533)
12. Ross HE, Glaser FB, Germanson T. The prevalence of psychiatric disorders in patients with alcohol and other drug problems. Arch Gen Psychiatry. 1988; 45(11):1023-1031. (Pubitemid 18261765)
13. Smail P, Stockwell T, Canter S, Hodgson R. Alcohol dependence and phobic anxiety states. I. A prevalence study. Br J Psychiatry. 1984;144:53-57. (Pubitemid 14214784)
14. Conger JJ. Alcoholism: theory, problem and challenge, II: reinforcement theory and the dynamics of alcoholism. Q J Stud Alcohol. 1956;17(2):296-305.
15. Quitkin FM, Rifkin A, Kaplan J, Klein DF. Phobic anxiety syndrome complicated by drug dependence and addiction: a treatable form of drug abuse. Arch Gen Psychiatry. 1972;27(2):159-162.
16. Thomas SE, Randall CL, Carrigan MH. Drinking to cope in socially anxious individuals: a controlled study. Alcohol Clin Exp Res. 2003;27(12):1937-1943. (Pubitemid 38005062)
17. Falk DE, Yi HY, Hilton ME. Age of onset and temporal sequencing of lifetime DSM-IV alcohol use disorders relative to comorbid mood and anxiety disorders. Drug Alcohol Depend. 2008;94(1-3):234-245.
18. Merikangas KR, Mehta RL, Molnar BE, Walters EE, Swendsen JD, Aguilar- Gaziola S, Bijl R, Borges G, Caraveo-Anduaga JJ, DeWit DJ, Kolody B, Vega WA, Wittchen HU, Kessler RC. Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology. Addict Behav. 1998;23(6):893-907. (Pubitemid 28443200)
19. Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J. γ-Aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry. 2006; 63(9):957-968. (Pubitemid 44330454)
20. Kushner MG. Relationship between alcohol problems and anxiety disorders. Am J Psychiatry. 1996;153(1):139-140. (Pubitemid 26026183)
21. Abrams K, Kushner M, Medina KL, Voight A. The pharmacologic and expectancy effects of alcohol on social anxiety in individuals with social phobia. Drug Alcohol Depend. 2001;64(2):219-231. (Pubitemid 32816965)
22. Carrigan MH, Randall CL. Self-medication in social phobia: a review of the alcohol literature. Addict Behav. 2003;28(2):269-284. (Pubitemid 36164859)
23. Schuckit MA, Hesselbrock V. Alcohol dependence and anxiety disorders: what is the relationship? Am J Psychiatry. 1994;151(12):1723-1734. (Pubitemid 24370891)
24. Tomlinson KL, Tate SR, Anderson KG, McCarthy DM, Brown SA. An examination of self-medication and rebound effects: psychiatric symptomatology before and after alcohol or drug relapse. Addict Behav. 2006;31(3):461-474. (Pubitemid 43288111)
25. Schuckit MA. Comorbidity between substance use disorders and psychiatric conditions. Addiction. 2006;101(suppl 1):76-88. (Pubitemid 44199498)
26. De Soto CB, O'Donnell WE, Allred LJ, Lopes CE. Symptomatology in alcoholics at various stages of abstinence. Alcohol Clin Exp Res. 1985;9(6):505-512. (Pubitemid 16176032)
27. Smith RJ, Aston-Jones G. Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence. Brain Struct Funct. 2008;213(1-2):43-61.
28. Kushner MG, Abrams K, Borchardt C. The relationship between anxiety disorders and alcohol use disorders: a review of major perspectives and findings. Clin Psychol Rev. 2000;20(2):149-171. (Pubitemid 30100430)
29. Labouvie E, Bates ME, Pandina RJ. Age of first use: its reliability and predictive utility. J Stud Alcohol. 1997;58(6):638-643. (Pubitemid 27498060)
30. Wilhelm K, Parker G. Sex differences in lifetime depression rates: fact or artefact? Psychol Med. 1994;24(1):97-111. (Pubitemid 24083686)
31. Grant BF, Moore TC, Kaplan K. Source and Accuracy Statement: Wave 1 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Bethesda, MD: National Institute on Alcohol Abuse and Alcoholism; 2003.
32. Grant BF, Dawson DA, Hasin DS. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV Version. Bethesda, MD: National Institute on Alcohol Abuse and Alcoholism; 2001.
33. Ruan WJ, Goldstein RB, Chou SP, Smith SM, Saha TD, Pickering RP, Dawson DA, Huang B, Stinson FS, Grant BF. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): reliability of new psychiatric diagnostic modules and risk factors in a general population sample. Drug Alcohol Depend. 2008;92(1-3):27-36. (Pubitemid 350218195)
34. Bolton JM, Robinson J, Sareen J. Self-medication of mood disorders with alcohol and drugs in the National Epidemiologic Survey on Alcohol and Related Conditions. J Affect Disord. 2009;115(3):367-375.
35. Robinson J, Sareen J, Cox BJ, Bolton J. Self-medication of anxiety disorders with alcohol and drugs: results from a nationally representative sample. J Anxiety Disord. 2009;23(1):38-45.
36. Robinson JA, Sareen J, Cox BJ, Bolton JM. Correlates of self-medication for anxiety disorders: results from the National Epidemiolgic Survey on Alcohol and Related Conditions. J Nerv Ment Dis. 2009;197(12):873-878.
37. Research Triangle Institute. Software for Survey Data Analysis (SUDAAN), Version 8.0. Research Triangle Park, NC: Research Triangle Institute; 2002.
38. Rockhill B, Newman B, Weinberg C. Use and misuse of population attributable fractions. Am J Public Health. 1998;88(1):15-19.
39. Young TK. Population Health: Concepts and Methods. 2nd ed. New York, NY: Oxford University Press; 2005.
40. Grant BF, Goldstein RB, Chou SP, Huang B, Stinson FS, Dawson DA, Saha TD, Smith SM, Pulay AJ, Pickering RP, Ruan WJ, Compton WM. Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. Mol Psychiatry. 2009;14(11):1051-1066.
41. Stockwell T, Smail P, Hodgson R, Canter S. Alcohol dependence and phobic anxiety states, II: a retrospective study. Br J Psychiatry. 1984;144:58-63.
42. Khantzian EJ. The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. Harv Rev Psychiatry. 1997;4(5):231- 244.
43. Hien DA, Jiang H, Campbell AN, Hu MC, Miele GM, Cohen LR, Brigham GS, Capstick C, Kulaga A, Robinson J, Suarez-Morales L, Nunes EV. Do treatment improvements in PTSD severity affect substance use outcomes? a secondary analysis from a randomized clinical trial in NIDA's Clinical Trials Network. Am J Psychiatry. 2010;167(1):95-101.
44. Glantz MD, Anthony JC, Berglund PA, Degenhardt L, Dierker L, Kalaydjian A, Merikangas KR, Ruscio AM, Swendsen J, Kessler RC. Mental disorders as risk factors for later substance dependence: estimates of optimal prevention and treatment benefits. Psychol Med. 2009;39(8):1365-1377.
45. Rosenbaum JF, Biederman J, Bolduc-Murphy EA, Faraone SV, Chaloff J, Hirshfeld DR, Kagan J. Behavioral inhibition in childhood: a risk factor for anxiety disorders. Harv Rev Psychiatry. 1993;1(1):2-16.
46. Schwartz CE, Snidman N, Kagan J. Adolescent social anxiety as an outcome of inhibited temperament in childhood. J Am Acad Child Adolesc Psychiatry. 1999; 38(8):1008-1015. (Pubitemid 29353036)
47. Stockwell T, Bolderston H. Alcohol and phobias. Br J Addict. 1987;82(9):971-979. (Pubitemid 17159789)
48. George DT, Nutt DJ, Dwyer BA, Linnoila M. Alcoholism and panic disorder: is the comorbidity more than coincidence? Acta Psychiatr Scand. 1990;81(2): 97-107. (Pubitemid 20192377)
49. Merikangas KR, He JP, Burstein M, Swanson SA, Avenevoli S, Cui L, Benjet C, Georgiades K, Swendsen J. Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication- Adolescent Supplement (NCS-A). J Am Acad Child Adolesc Psychiatry. 2010; 49(10):980-989.
50. Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication [published correction appears in Arch Gen Psychiatry. 2005;62(7):768]. Arch Gen Psychiatry. 2005;62(6):593-602. (Pubitemid 40973434)
51. Leeies M, Pagura J, Sareen J, Bolton JM. The use of alcohol and drugs to self-medicate symptoms of posttraumatic stress disorder. Depress Anxiety. 2010; 27(8):731-736.