Debate does a reversible penumbra exist in intracerebral haemorrhage?

British Journal of Neurosurgery

Volumn 25, Issue 4, 2011, Pages 523-525

  Kirkman, Matthew Anthony ^a  

^a SALFORD ROYAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

imaging; Intracerebral haemorrhage; ischaemic penumbra; metabolic derangement; microdialysis; perihaematomal hypoperfusion

Indexed keywords

ARTICLE; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; BRAIN PERFUSION; COMPUTER ASSISTED TOMOGRAPHY; CONSERVATIVE TREATMENT; DIFFUSION WEIGHTED IMAGING; ELECTROENCEPHALOGRAM; HUMAN; HYPERTENSION; INTRACRANIAL PRESSURE; ISCHEMIC PENUMBRA; MEAN ARTERIAL PRESSURE; NEUROSURGERY; NONHUMAN; OXYGEN EXTRACTION FRACTION; PERFUSION WEIGHTED IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; SEIZURE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TRAUMATIC BRAIN INJURY;

BLOOD FLOW VELOCITY; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; CEREBROVASCULAR CIRCULATION; DIAGNOSTIC IMAGING; HUMANS; METABOLIC DISEASES;

EID: 79961198903     PISSN: 02688697     EISSN: 1360046X     Source Type: Journal    
DOI: 10.3109/02688697.2011.578773     Document Type: Article

References (25)

1. van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 2010;9(2):167-76.
2. Qureshi AI, Mendelow AD, Hanley DF. Intracerebral haemorrhage. Lancet 2009;373:1632-44.
3. Elliott J, Smith M. The acute management of intracerebral haemorrhage: a clinical review. Anesth Analg 2010;110(5): 1419-27.
4. Mendelow AD. Mechanisms of ischemic brain damage with intracerebral hemorrhage. Stroke 1993;24(suppl 1):I115-7. (Pubitemid 23350067)
5. Kingman TA, Mendelow AD, Graham DI, Teasdale GM. Experimental intracerebral mass: time-related effects on local cerebral blood-flow. J Neurosurg 1987;67:732-8. (Pubitemid 17161405)
6. Nehls DG, Mendelow AD, Graham DI, Teasdale GM, McCulloch J. Experimental intracerebral haemorrhage: early removal of a spontaneous mass lesion improves late outcome. Neurosurgery 1990;27:675-82.
7. Herweh C, Juttler E, Schellinger PD, Klotz E, Jenetzky E, Orakcioglu B, Sartor K, Schramm P. Evidence against a perihemorrhagic penumbra provided by perfusion computer tomography. Stroke 2007;38:2941-2947. (Pubitemid 350035687)
8. Herweh C, Juttler E, Schellinger PD, Klotz E, Schramm P. Perfusion CT in hyperacute cerebral haemorrhage within 3 hours after symptom onset: is there an early perihemorrhagic penumbra? J Neuroimaging 2010;20(4):350-3.
9. Schellinger PD, Fiebach JB, Hoffman K, et al. Stroke MRI in intracerebral haemorrhage: is there a perihaemorrhagic penumbra? Stroke 2003;34:1674-80.
10. Orakcioglu B, Becker K, Sakowitz OW, et al. MRI of the Perhemorrhagic zone in a Rat ICH model: effect of hematoma evacuation. Neurocrit Care 2008;8:448-55.
11. Mayer SA, Lignelli A, Fink ME, et al. Perilesional blood flow and edema formation in acute intracerebral hemorrhage: a SPECT study. Stroke 1998;29:1791-98. (Pubitemid 28399965)
12. Tayal AH, Gupta R, Yonas H, et al. Quantitative perihematomal blood flow in spontaneous intracerebral hemorrhage predicts in-hospital functional outcome. Stroke 2007;38:319-24. (Pubitemid 46184302)
13. Qureshi AI, Wilson DA, Hanley DF, Traystman RJ. No evidence for an ischemic penumbra in massive experimental intracerebral hemorrhage. Neurology 1999;52(2):266-72. (Pubitemid 29059050)
14. Pascual AM, Lopez-Mut JV, Benllock V, Chamarro R, Soler J, Lainez MJA. Perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage at baseline and during the 1st and 2nd week: a longitudinal study. Cerebrovasc Dis 2007;23:6-13. (Pubitemid 46112796)
15. Faindardi E, Borrelli M, Saletti A, et al. CT perfusion mapping of hemodynamic disturbances associated to acute spontaneous intracerebral hemorrhage. Neuroradiology 2008; 50:729-40.
16. Zazulia AR, Diringer MN, Videen TO, et al. Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage. J Cereb Blood Flow Metab 2001;21:804-10. (Pubitemid 32613534)
17. Kim-Han JS, Kopp SJ, Dugan LL, Diringer MN. Perihematomal mitochondrial dysfunction after intracerebral hemorrhage. Stroke 2006;37:2457-62. (Pubitemid 44454660)
18. Vespa P, Bergsneider M, Hattori N, et al. Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab 2005;25:763-74. (Pubitemid 40705611)
19. Zazulia AR, Videen TO, Powers WJ. Transient focal increase in perihematomal glucose metabolism after acute human intracerebral hemorrhage. Stroke 2009;40:1638-43.
20. Vespa P, O'Phelan K, Mirabelli J, et al. Acute seizures after intracerebral hemorrhage: a factor in progressive midline shift and outcome. Neurology 2003;60:1441-6. (Pubitemid 36554803)
21. Claassen J, Jette N, Chum F, et al. Electrographic seizures and periodic discharges after intracerebral hemorrhage. Neurology 2007;69:1356-65. (Pubitemid 47482450)
22. Fabricius M, Fuhr S, Bhatia R, et al. Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 2006;129:778-90. (Pubitemid 43278239)
23. Nilsson OG, Polito A, Saveland H, Understedt U, Nordstrom CH. Are primary supratentorial intracerebral hemorrhages surrounded by a biochemical penumbra? A microdialysis study. Neurosurgery 2006;59(3):521-8.
24. Davis SM, Broderick J, Hennerici M, et al. Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology 2006;66(8):1175-81. (Pubitemid 43739699)
25. Powers WJ, Zazulia AR, Videen TO, et al. Autoregulation of cerebral blood flow surround acute (6 to 22 hours) intracerebral hemorrhage. Neurology 2001;10:18-24. (Pubitemid 32634845)