Stroke MRI in intracerebral hemorrhage: Is there a perihemorrhagic penumbra?

Stroke

Volumn 34, Issue 7, 2003, Pages 1674-1679

  Schellinger, Peter D ^a,b   Fiebach, Jochen B ^a   Hoffmann, Katrin ^a   Becker, Kristina ^a   Orakcioglu, Berk ^a   Kollmar, Rainer ^a   Jüttler, Eric ^a   Schramm, Peter ^a   Schwab, Stefan ^a   Sartor, Klaus ^a   Hacke, Werner ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Intracerebral hemorrhage; Magnetic resonance imaging, diffusion weighted; Magnetic resonance imaging, perfusion weighted; Penumbra; Risk

Indexed keywords

ADULT; AGED; APOPTOSIS; ARTICLE; BRAIN HEMORRHAGE; BRAIN PERFUSION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DISEASE SEVERITY; FEMALE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; RATING SCALE; STROKE;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; BRAIN; CEREBRAL HEMORRHAGE; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR CIRCULATION; DISEASE PROGRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0038168536     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000076010.10696.55     Document Type: Article

References (29)

1. Diringer MN. Intracerebral hemorrhage: pathophysiology and management. Crit Care Med. 1993;21:1591-1603.
2. Qureshi AI, Tuhrim S, Broderick JP, Batjer HH, Hondo H, Hanley DF. Spontaneous intracranial hemorrhage. N Engl J Med. 2001;344:1450-1460.
3. Fernandes HM, Gregson B, Siddique S, Mendelow AD. Surgery in intracerebral hemorrhage: the uncertainty continues. Stroke. 2000;31:2511-2516.
4. Bullock R, Brock Utne J, van Dellen J, Blake G. Intracerebral hemorrhage in a primate model: effect on regional cerebral blood flow. Surg Neurol. 1988;29:101-107.
5. Mun Bryce S, Kroh FO, White J, Rosenberg GA. Brain lactate and pH dissociation in edema: 1H- and 31P-NMR in collagenase-induced hemorrhage in rats. Am J Physiol. 1993;265:R697-R702.
6. Deinsberger W, Vogel J, Fuchs C, Auer LM, Kuschinsky W, Boker DK. Fibrinolysis and aspiration of experimental intracerebral hematoma reduces the volume of ischemic brain in rats. Neurol Res. 1999;21:517-523.
7. Ogawa T, Hatazawa J, Inugami A, Murakami M, Fujita H, Shimosegawa E, Noguchi K, Okudera T, Kanno I, Uemura K, et al. Carbon-11-methionine PET evaluation of intracerebral hematoma: distinguishing neoplastic from non-neoplastic hematoma. J Nucl Med. 1995;36:2175-2179.
8. Zazulia AR, Diringer MN, Videen TO, Adams RE, Yundt K, Aiyagari V, Grubb RL Jr, Powers WJ. Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage. J Cereb Blood Flow Metab. 2001;21:804-810.
9. Kidwell CS, Saver JL, Mattiello J, Warach S, Liebeskind DS, Starkman S, Vespa PM, Villablanca JP, Martin NA, Frazee J, Alger JR. Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intra-cerebral hemorrhage. Neurology. 2001;57:1611-1617.
10. Schellinger PD, Fiebach JB, Jansen O, Ringleb PA, Mohr A, Steiner T, Heiland S, Schwab S, Pohlers O, Ryssel H, Orakcioglu B, Sartor K, Hacke W. Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann Neurol. 2001;49:460-469.
11. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304-1305.
12. Powers WJ, Zazulia AR, Videen TO, Adams RE, Yundt KD, Aiyagari V, Grubb RL Jr, Diringer MN. Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage. Neurology. 2001;57:18-24.
13. Perthen JE, Calamante F, Gadian DG, Connelly A. Is quantification of bolus tracking MRI reliable without deconvolution? Magn Res Med. 2002;47:61-67.
14. Morgenstern LB, Frankowski RF, Shedden P, Pasteur W, Grotta JC. Surgical treatment for intracerebral hemorrhage (STICH). Stroke. 1998;51:1359-1363.
15. Carhuapoma JR, Wang PY, Beauchamp NJ, Keyl PM, Hanley DF, Barker PB. Diffusion-weighted MRI and proton MR spectroscopic imaging in the study of secondary neuronal injury after intracerebral hemorrhage. Stroke. 2000;31:726-732.
16. Ropper AH, Zervas NT. Cerebral blood flow after experimental basal ganglia hemorrhage. Ann Neurol. 1982;11:266-271.
17. Videen TO, Dunford-Shore JE, Diringer MN, Powers WJ. Correction for partial volume effects in regional blood flow measurements adjacent to hematomas in humans with intracerebral hemorrhage: implementation and validation. J Comput Assist Tomogr. 1999;23:248-256.
18. Castillo J, Dávalos A, Álvarez-Sabín J, Pumar JM, Leira R, Silva Y, Montaner J, Kase CS. Molecular signatures of brain injury after intracerebral hemorrhage. Neurology. 2002;58:624-629.
19. Qureshi AI, Wilson DA, Hanley DF, Traystman RJ. No evidence for an ischemic penumbra in massive experimental intracerebral hemorrhage. Neurology. 1999;52:266-272.
20. Schellinger PD, Jansen O, Fiebach JB, Hacke W, Sartor K. A standardized MRI stroke protocol: comparison with CT in hyperacute intracerebral hemorrhage. Stroke. 1999;30:765-768.
21. Linfante I, Llinas RH, Caplan LR, Warach S. MRI features of intracerebral hemorrhage within 2 hours from symptom onset. Stroke. 1999;30:2263-2267.
22. Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, Ölkers T, Hirsch JG, Heiland S, Jansen O, et al. Stroke MRI is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. N Engl J Med. 2003:submitted for publication.
23. Nighoghossian N, Hermier M, Adeleine P, Blanc-Lasserre K, Derex L, Honnorat J, Philippeau F, Dugor JF, Froment JC, Trouillas P. Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke: a gradient-echo T2*-weighted brain MRI study. Stroke. 2002;33:735-742.
24. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, et al. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 2002;33:95-98.
25. Neumann-Haefelin T, Wittsack HJ, Wenserski F, Siebler M, Seitz RJ, Moedder U, Freund HJ. Diffusion- and perfusion-weighted MRI: the DWI/PWI mismatch region in acute stroke. Stroke. 1999;30:1591-1597.
26. Nath FP, Kelly PT, Jenkins A, Mendelow AD, Graham DI, Teasdale GM. Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry. J Neurosurg. 1987;66:555-562.
27. Gebel JM Jr, Jauch EC, Brott TG, Khoury J, Sauerbeck L, Salisbury S, Spilker J, Tomsick TA, Duldner J, Broderick JP. Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral hemorrhage. Stroke. 2002;33:2636-2641.
28. Hirano T, Read SJ, Abbott DF, Sachinidis JI, Tochon-Danguy HJ, Egan GF, Bladin CF, Scott AM, McKay WJ, Donnan GA. No evidence of hypoxic tissue on 18F-fluoromisonidazole PET after intracerebral hemorrhage. Neurology. 1999;53:2179-2182.
29. Chu WJ, Mason GF, Pan JW, Hetherington HP, Liu HG, San Pedro EC, Mountz JM. Regional cerebral blood flow and magnetic resonance spectroscopic imaging findings in diaschisis from stroke. Stroke. 2002;33:1243-1248.