Alkali-metal mediated zincation of N-heterocyclic substrates using the lithium zincate complex, (THF)Li(TMP)Zn(tBu)2 and applications in in situ cross coupling reactions

Tetrahedron Letters

Volumn 52, Issue 36, 2011, Pages 4590-4594

  Blair, Victoria L ^a   Blakemore, David C ^b   Hay, Duncan ^b   Hevia, Eva ^a   Pryde, David C ^b  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Lithium; Metallation; Mixed metal reagents; N Heterocycles; Zincation

Indexed keywords

ALKALI METAL; HETEROCYCLIC COMPOUND; HYDROGEN; IODINE; LITHIUM; LITHIUM ZINCATE COMPLEX; PALLADIUM; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; METALLATION;

EID: 79961173024     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.06.090     Document Type: Article

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