Single high-dose treatment with glucosaminyl-muramyl dipeptide is ineffective in treating ankylosing spondylitis

Rheumatology International

Volumn 31, Issue 8, 2011, Pages 1101-1103

  Britanova, Olga V ^a   Staroverov, Dmitriy B ^a   Chkalina, Anna V ^a   Kotlobay, Alexei A ^a   Zvezdova, Ekaterina S ^a   Bochkova, Anna G ^b   Chudakov, Dmitriy M ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b V A NASONOVA RESEARCH INSTITUTE OF RHEUMATOLOGY   (Russian Federation)

Author keywords

Ankylosing spondylitis; Autoimmune T cells; Likopid; Muramyl dipeptide; NOD2 receptor; TNF alpha level

Indexed keywords

GLUCOSAMINYLMURAMYL DIPEPTIDE; INFLIXIMAB; LIKOPID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANKYLOSING SPONDYLITIS; APOPTOSIS; ARTICLE; BLOOD SAMPLING; BONE SCINTISCANNING; CASE REPORT; CD8+ T LYMPHOCYTE; DRUG MEGADOSE; FEVER; FLOW CYTOMETRY; HUMAN; LYMPHOCYTE CLONE; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; TREATMENT OUTCOME;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIRHEUMATIC AGENTS; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; SPONDYLITIS, ANKYLOSING; T-LYMPHOCYTE SUBSETS; TREATMENT FAILURE;

EID: 79961171629     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-010-1663-3     Document Type: Article

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