Contextual and psychosocial influences on antiretroviral therapy adherence in rural Zimbabwe: Towards a systematic framework for programme planners

International Journal of Health Planning and Management

Volumn 26, Issue 3, 2011, Pages 296-318

  Skovdal, Morten ^a   Campbell, Catherine ^a   Nhongo, Kundai ^b   Nyamukapa, Constance ^b,c   Gregson, Simon ^b,c  

^a LONDON SCHOOL OF ECONOMICS   (United Kingdom)

^b BIOMEDICAL RESEARCH AND TRAINING INSTITUTE   (Zimbabwe)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Adherence; Antiretroviral therapy; HIV and AIDS; Social context; Treatment; Zimbabwe

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; COMPLIANCE; DISEASE TREATMENT; DRUG RESISTANCE; HEALTH POLICY; HEALTH RISK; HEALTH WORKER; HUMAN IMMUNODEFICIENCY VIRUS; POLICY IMPLEMENTATION; POVERTY; PSYCHOLOGY; RESOURCE AVAILABILITY; RURAL AREA; SOCIAL IMPACT;

ARTICLE; HEALTH CARE QUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERVIEW; MALE; METHODOLOGY; PATIENT COMPLIANCE; POVERTY; PROGRAM DEVELOPMENT; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; RURAL POPULATION; SOCIAL SUPPORT; STATISTICS; TRAFFIC AND TRANSPORT;

ANTI-HIV AGENTS; HIV INFECTIONS; HUMANS; INTERVIEWS AS TOPIC; MALE; MEDICATION ADHERENCE; POVERTY; PROGRAM DEVELOPMENT; PSYCHOLOGY; QUALITY OF HEALTH CARE; RURAL POPULATION; SOCIAL SUPPORT; TRANSPORTATION;

ZIMBABWE;

EID: 79961167211     PISSN: 07496753     EISSN: 10991751     Source Type: Journal    
DOI: 10.1002/hpm.1082     Document Type: Article

References (44)

1. Adato M, Bassett L. 2008. What is the Potential of Cash Transfers to Strengthen Families Affected by HIV and AIDS? A Review of the Evidence on Impacts and Key Policy Debates. International Food Policy Research Institute (IFPRI): Washinton, D.C.
2. Adewuya AO, Afolabi MO, Ola BA, Ogundele OA, Ajibare AO, Oladipo BF, et al. 2010. The effect of psychological distress on medication adherence in persons with HIV infection in Nigeria. Psychosomatics 51(1): 68-73.
3. Attaran A. 2007. Adherence to HAART: Africans take medicines more faithfully than North Americans. PLoS Medicine 4(2): e83.
4. Attride-Stirling J. 2001. Thematic networks: an analytic tool for qualitative research. Qualitative Research 1(3): 385-405.
5. Bisson GP, Rowh A, Weinstein R, Gaolathe T, Frank I, Gross R. 2008. Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in Botswana. Journal of Acquired Immune Deficiency Syndromes 49(1): 107-110. DOI: 110.1097/QAI.1090b1013e3181820141.
6. Campbell C, Cornish F. 2010. Towards a 'fourth generation' of approaches to HIV/AIDS management: creating contexts for effective community mobilisation. AIDS Care, 22(2): 1569-1579.
7. Campbell C, Scott K, Skovdal M, Chirwa C, Mupambireyi Z, Gregson S. 2011a. How do notions of 'a good patient' impact on patient/nurse relationships and ART adherence in Zimbabwe., in preparation.
8. Campbell C, Skovdal M, Mugurungi O, Nyamukapa C, Gregson S. 2011b. "We, the AIDS people.": through what mechanisms have antiretroviral therapy created a context for ARV users to resist stigma and construct positive identities? American Journal of Public Health, 101(6): 1004-1010.
9. Chalker J, Andualem T, Minzi O, Ntaganira J, Ojoo A, Waako P, et al. 2008. Monitoring adherence and defaulting for antiretroviral therapy in 5 East African countries: an urgent need for standards. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill.) 7(4): 193-199.
10. Dahab M, Charalambous S, Hamilton R, Fielding K, Kielmann K, Churchyard G, et al. 2008. "That is why I stopped the ART": patients & providers' perspectives on barriers to end enablers of HIV treatment adherence in a South African workplace programme. BMC Public Health 8(63): 1-6.
11. Fitzgerald M, Collumbien M, Hosegood V. 2010. "No one can ask me 'Why do you take that stuff?'": men's experiences of antiretroviral treatment in South Africa. AIDS Care 22(3): 355-360.
12. Flick U. 2002. An Introduction to Qualitative Research, 2nd edn. Sage: London.
13. Flyvbjerg B. 2001. Making Social Science Matter: Why Social Inquiry Fails and How It Can Count Again. Cambridge University Press: New York.
14. Gill C, Davidson H, Jonathon S, Donald T, Sabin L. 2005. No room for complacency about adherence to antiretroviral therapy in sub-Saharan Africa. AIDS 19(12): 1243-1249.
15. Goudge J, Ngoma B, Manderson L, Schneider H. 2009. Stigma, identity and resistance among people living with HIV in South Africa. Journal of Social Aspects HIV/AIDS 6(3): 94-104.
16. Gregson S, Gonese E, Hallett TB, Taruberekera N, Hargrove JW, Lopman B, et al. 2010. HIV decline in Zimbabwe due to reductions in risky sex? Evidence from a comprehensive epidemiological review. International Journal of Epidemiology 39: 1311-1323.
17. Hardon AP, Akurut D, Comoro C, Ekezie C, Irunde HF, Gerrits T, et al. 2007. Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS Care 19(5): 658-665.
18. Kempf M-C, Pisu M, Dumcheva A, Westfall AO, Kilby JM, Saag MS. 2009. Gender differences in discontinuation of antiretroviral treatment regimens. Journal of Acquired Immune Deficiency Syndromes 52(3): 336-341. DOI: 310.1097/QAI.1090b1013e3181b1628be.
19. Kip E, Ehlers V, van der Wal D. 2009. Patients' adherence to anti-retroviral therapy in Botswana. Journal of Nursing Scholarship 41(2): 149-157.
20. Krebs DW, Chi BH, Mulenga Y, Morris M, Cantrell RA, Mulenga L, et al. 2008. Community-based follow-up for late patients enrolled in a district-wide programme for antiretroviral therapy in Lusaka, Zambia. AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV 20(3): 311-317.
21. McCoy D, Chopra M, Loewenson R, Aitken J-M, Ngulube T, Muula A, et al. 2005. Expanding access to antiretroviral therapy in sub-Saharan Africa: avoiding the pitfalls and dangers, capitalizing on the opportunities. American Journal of Public Health 95(1): 18-22.
22. Mills EJ, Nachega JB, Bangsberg DR, Singh S, Rachlis B, Wu P, et al. 2006a. Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators. PLoS Medicine 3: e438.
23. Mills EJ, Nachega JB, Buchan I, Orbinski J, Attaran A, Singh S, et al. 2006b. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA 296: 679-690.
24. Mshana G, Wamoyi J, Busza J, Zaba B, Changalucha J, Kaluvya S, et al. 2006. Barriers to accessing antiretroviral therapy in Kisesa, Tanzania: a qualitative study of early rural referrals to the national program. AIDS Patient Care and STDs 20(9): 649-657.
25. Murray LK, Semrau K, McCurley E, Thea DM, Scott N, Mwiya M, et al. 2009. Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women: a qualitative study. AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV 21(1): 78-86.
26. Nachega J, Knowlton A, Deluca A, Schoeman J, Watkinson L, Efron A, et al. 2006. Treatment supporter to improve adherence to antiretroviral therapy in HIV-infected South African adults. Journal of Acquired Immune Deficiency Syndromes 43(1): 127-133.
27. Nsigaye R, Wringe A, Roura M, Kalluvya S, Urassa M, Busza J, et al. 2009. From HIV diagnosis to treatment: evaluation of a referral system to promote and monitor access to antiretroviral therapy in rural Tanzania. Journal of the International AIDS Society 12(1): 31.
28. Peltzer K, Preez N, Ramlagan S, Anderson J. 2010. Antiretroviral treatment adherence among HIV patients in KwaZulu-Natal, South Africa. BMC Public Health 10: 111.
29. Posse M, Meheus F, van Asten H, van der Ven A, & Baltussen R. 2008. Barriers to access to antiretroviral treatment in developing countries: a review. Tropical Medicine & International Health 13(7): 904-913.
30. Rosen S, Fox MP, Gill CJ. 2007. Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review. PLoS Medicine 4(10): e298.
31. Roura M, Busza J, Wringe A, Mbata D, Urassa M, Zaba B. 2009. Barriers to sustaining antiretroviral treatment in Kisesa, Tanzania: a follow-up study to understand attrition from the antiretroviral program. AIDS Patient Care and STDs 23: 203-210.
32. Sanjobo N, Frich J, Fretheim A. 2008. Barriers and facilitators to patients' adherence to antiretroviral treatment in Zambia: a qualitative study. SAHARA-J 4(2): 136-143.
33. Skovdal M, Campbell C, Madanhire C, Mupambireyi Z, Nyamukapa C, Gregson S. 2011. Masculinity as a barrier to men's use of HIV services in Zimbabwe. Globalisation and Health 7: 13.
34. Skovdal M, Campbell C, Madanhire C, Nyamukapa C, Gregson S. 2011. When masculinity interferes with women's treatment of HIV infection: A qualitative study about adherence to antiretroviral therapy in Zimbabwe. Journal of the International AIDS Society, 14: 29. [accessed on 9 June 2011].
35. UNAIDS. 2010. Zimbabwe-2010 Country Progress Report. UNAIDS: Geneva. [accessed on 9 April 2010].
36. Uzochukwu BSC, Onwujekwe OE, Onoka AC, Okoli C, Uguru NP, Chukwuogo OI. 2009. Determinants of non-adherence to subsidized anti-retroviral treatment in southeast Nigeria. Health Policy Plan 24(3): 189-196. DOI: 10.1093/heapol/czp006.
37. Ware NC, Idoko J, Kaaya S, Biraro IA, Wyatt MA, Agbaji O, et al. 2009. Explaining adherence success in sub-Saharan Africa: an ethnographic study. PLoS Medicine 6(1): e1000011.
38. Watt M, Maman S, Jacobson M, Laiser J, John M. 2009a. Missed opportunities for religious organizations to support people living with HIV/AIDS: findings from Tanzania. AIDS Patient Care and STDs 23(5): 389-394.
39. Watt MH, Maman S, Earp JA, Eng E, Setel PW, Golin CE, et al. 2009b. "It's all the time in my mind": facilitators of adherence to antiretroviral therapy in a Tanzanian setting. Social Science & Medicine 68(10): 1793-1800.
40. Weiser S, Wolfe W, Bangsberg D, Thior I, Gilbert P, Makhema J, et al. 2003. Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana. Journal of Acquired Immune Deficiency Syndromes 34(3): 281-288.
41. WHO. 2010. World Health Statistics 2010. WHO Press: Geneva. [accessed on 5 December 2010].
42. WHO, UNAIDS, UNICEF. 2009. Towards Universal Access: Scaling up priority HIV/AIDs interventions in the health sector-Progress Report, September 2009 edn. WHO Press: Geneva [accessed on 5 December 2010].
43. Wringe A, Roura M, Urassa M, Busza J, Athanas V, Zaba B. 2009. Doubts, denial and divine intervention: understanding delayed attendance and poor retention rates at a HIV treatment programme in rural Tanzania. AIDS Care 21: 632-637.
44. Zimbabwe Ministry of Health and Child Welfare. 2009. Zimbabwe National HIV and AIDS Estimates. Zimbabwe Ministry of Health and Child Welfare: Harare.