New insights from hemichordate genomes: Prebilaterian origin and parallel modifications in the paired domain of the Pax gene eyegone

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution

Volumn 316 B, Issue 6, 2011, Pages 387-392

  Friedrich, Markus ^a,b   Caravas, Jason ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DROSOPHILA PROTEIN; EYE GONE PROTEIN, DROSOPHILA; EYE PROTEIN; HOMEODOMAIN PROTEIN; ISOPROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; REPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; COMPARATIVE STUDY; DROSOPHILA; GENE EXPRESSION REGULATION; GENETICS; GENOME; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MUTATION; TRANSGENIC ANIMAL;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; EYE PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; HOMEODOMAIN PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PAIRED BOX TRANSCRIPTION FACTORS; PROTEIN ISOFORMS; REPRESSOR PROTEINS;

ECHINOIDEA; HEXAPODA; METAZOA; VERTEBRATA;

EID: 79961146411     PISSN: 15525007     EISSN: 15525015     Source Type: Journal    
DOI: 10.1002/jez.b.21412     Document Type: Article

References (24)

1. Aldaz S, Morata G, Azpiazu N. 2003. The Pax-homeobox gene eyegone is involved in the subdivision of the thorax of Drosophila. Development 130:4473-4482.
2. Bao R, Friedrich M. 2009. Molecular evolution of the Drosophila retinome: exceptional gene gain in the higher Diptera. Mol Biol Evol 26:1273-1287.
3. Chi N, Epstein JA. 2002. Getting your Pax straight: Pax proteins in development and disease. Trends Genet 18:41-47.
4. Czerny T, Busslinger M. 1995. DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). Mol Cell Biol 15:2858.
5. Czerny T, Schaffner G, Busslinger M. 1993. DNA sequence recognition by Pax proteins: Bipartite structure of the paired domain and its binding site. Genes Dev 7:2048-2061.
6. Epstein J, Glaser T, Cai J, Jepeal L, Walton D, Maas R. 1994. Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev 8:2022.
7. Glardon S, Holland LZ, Gehring WJ, Holland ND. 1998. Isolation and developmental expression of the Amphioxus pax-6 gene (amphipax-6): Insights into eye and photoreceptor evolution. Development 125:2701-2710.
8. Groger H, Callaerts P, Gehring WJ, Schmid V. 2000. Characterization and expression analysis of an ancestor-type Pax gene in the hydrozoan jellyfish Podocoryne carnea. Mech Dev 94:157-169.
9. Heffer A, Shultz JW, Pick L. 2010. Surprising flexibility in a conserved Hox transcription factor over 550 million years of evolution. Proc Natl Acad Sci USA 107:18040-18045.
10. Huelsenbeck JP, Ronquist F. 2001. Mrbayes: Bayesian inference of phylogenetic trees. Bioinformatics 17:754-755.
11. Jun S, Wallen RV, Goriely A, Kalionis B, Desplan C. 1998. Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition. Proc Natl Acad Sci USA 95:13720-13725.
12. Kurowski M, Bujnicki J. 2003. Genesilico protein structure prediction meta-server. NAR 31:3305.
13. Lynch V, Wagner G. 2011. Revisiting a classic example of transcription factor functional equivalence: are eyeless and Pax6 functionally equivalent or divergent? J Exp Zool B (Mol Dev Evol) 316B:93-98.
14. Maier H, Ostraat R, Parenti S, Fitzsimmons D, Abraham L, Garvie C, Hagman J. 2003. Requirements for selective recruitment of Ets proteins and activation of mb 1/Ig-α gene transcription by Pax 5 (BSAP). NAR 31:5483.
15. Matus D, Pang K, Daly M, Martindale M. 2007. Expression of Pax gene family members in the anthozoan cnidarian, Nematostella vectensis. Evol Dev 9:25-38.
16. Pichaud F, Desplan C. 2002. Pax genes and eye organogenesis. Curr Opin Genet Dev 12:430-434.
17. Rodrigues AB, Moses K. 2004. Growth and specification: Fly Pax6 homologs eyegone and eyeless have distinct functions. Bioessays 26:600-603.
18. Ronquist F, Huelsenbeck JP. 2003. Mrbayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19:1572-1574.
19. Short S, Holland L. 2008. The evolution of alternative splicing in the Pax family: The view from the basal chordate Amphioxus. J Mol Evol 66:605-620.
20. Sun H, Merugu S, Gu X, Kang YY, Dickinson DP, Callaerts P, Li W-H. 2002. Identification of essential amino acid changes in paired domain evolution using a novel combination of evolutionary analysis and in vitro and in vivo studies. Mol Biol Evol 19:1490-1500.
21. Xu W, Rould MA, Jun S, Desplan C, Pabo CO. 1995. Crystal structure of a paired domain-DNA complex at 2.5 a resolution reveals structural basis for Pax developmental mutations. Cell 80:639-650.
22. Xu H, Rould M, Xu W, Epstein J, Maas R, Pabo C. 1999. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev 13:1263.
23. Yao JG, Sun YH. 2005. Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development. Embo J 24:2602-2612.
24. ZarinKamar N, Yang X, Bao R, Friedrich F, Beutel R, Friedrich M. The Pax gene eyegone facilitates repression of eye development in Tribolium. EvoDevo, in press.