메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in Hepatocellular carcinoma development

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; LUCIFERASE; MICRORNA; MICRORNA 146A; MICRORNA 190; MICRORNA 26A; MICRORNA 29C; RNA; UNCLASSIFIED DRUG; PRIMER DNA; TRANSACTIVATOR PROTEIN;

EID: 79961136142     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022888     Document Type: Article
Times cited : (66)

References (68)
  • 1
    • 0030902570 scopus 로고    scopus 로고
    • Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma
    • Feitelson MA, Duan LX, (1997) Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. Am J Pathol 150: 1141-1157.
    • (1997) Am J Pathol , vol.150 , pp. 1141-1157
    • Feitelson, M.A.1    Duan, L.X.2
  • 2
    • 33646337650 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and hepatitis B virus
    • Chan HL, Sung JJ, (2006) Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 26: 153-161.
    • (2006) Semin Liver Dis , vol.26 , pp. 153-161
    • Chan, H.L.1    Sung, J.J.2
  • 3
    • 4744351642 scopus 로고    scopus 로고
    • Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2
    • Cheng AS, Chan HL, Leung WK, To KF, Go MY, et al. (2004) Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2. Mod Pathol 17: 1169-1179.
    • (2004) Mod Pathol , vol.17 , pp. 1169-1179
    • Cheng, A.S.1    Chan, H.L.2    Leung, W.K.3    To, K.F.4    Go, M.Y.5
  • 4
    • 0029147911 scopus 로고
    • The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors
    • Doria M, Klein N, Lucito R, Schneider RJ, (1995) The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. EMBO J 14: 4747-4757.
    • (1995) EMBO J , vol.14 , pp. 4747-4757
    • Doria, M.1    Klein, N.2    Lucito, R.3    Schneider, R.J.4
  • 5
    • 0035896631 scopus 로고    scopus 로고
    • X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway
    • Diao J, Khine AA, Sarangi F, Hsu E, Iorio C, et al. (2001) X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway. J Biol Chem 276: 8328-8340.
    • (2001) J Biol Chem , vol.276 , pp. 8328-8340
    • Diao, J.1    Khine, A.A.2    Sarangi, F.3    Hsu, E.4    Iorio, C.5
  • 6
    • 48549099121 scopus 로고    scopus 로고
    • COX-2 mediates hepatitis B virus X protein abrogation of p53-induced apoptosis
    • Cheng AS, Yu J, Lai PB, Chan HL, Sung JJ, (2008) COX-2 mediates hepatitis B virus X protein abrogation of p53-induced apoptosis. Biochem Biophys Res Commun 374: 175-180.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 175-180
    • Cheng, A.S.1    Yu, J.2    Lai, P.B.3    Chan, H.L.4    Sung, J.J.5
  • 7
    • 0028890351 scopus 로고
    • Hepatitis B virus transactivator protein X interacts with the TATA-binding protein
    • Qadri I, Maguire HF, Siddiqui A, (1995) Hepatitis B virus transactivator protein X interacts with the TATA-binding protein. Proc Natl Acad Sci USA 92: 1003-1007.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1003-1007
    • Qadri, I.1    Maguire, H.F.2    Siddiqui, A.3
  • 8
    • 33947528120 scopus 로고    scopus 로고
    • The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription
    • Cougot D, Wu Y, Cairo S, Caramel J, Renard CA, et al. (2007) The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription. J Biol Chem 282: 4277-4287.
    • (2007) J Biol Chem , vol.282 , pp. 4277-4287
    • Cougot, D.1    Wu, Y.2    Cairo, S.3    Caramel, J.4    Renard, C.A.5
  • 9
    • 34247190634 scopus 로고    scopus 로고
    • Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein
    • Park IY, Sohn BH, Yu E, Suh DJ, Chung YH, et al. (2007) Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology 132: 1476-1494.
    • (2007) Gastroenterology , vol.132 , pp. 1476-1494
    • Park, I.Y.1    Sohn, B.H.2    Yu, E.3    Suh, D.J.4    Chung, Y.H.5
  • 10
    • 0033607041 scopus 로고    scopus 로고
    • Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx
    • Sirma H, Giannini C, Poussin K, Paterlini P, Kremsdorf D, et al. (1999) Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. Oncogene 18: 4848-4859.
    • (1999) Oncogene , vol.18 , pp. 4848-4859
    • Sirma, H.1    Giannini, C.2    Poussin, K.3    Paterlini, P.4    Kremsdorf, D.5
  • 11
    • 0035502957 scopus 로고    scopus 로고
    • Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues
    • Tu H, Bonura C, Giannini C, Mouly H, Soussan P, et al. (2001) Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues. Cancer Res 61: 7803-7810.
    • (2001) Cancer Res , vol.61 , pp. 7803-7810
    • Tu, H.1    Bonura, C.2    Giannini, C.3    Mouly, H.4    Soussan, P.5
  • 12
    • 0042671276 scopus 로고    scopus 로고
    • Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection
    • Iavarone M, Trabut JB, Delpuech O, Carnot F, Colombo M, et al. (2003) Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection. J Hepatol 39: 253-261.
    • (2003) J Hepatol , vol.39 , pp. 253-261
    • Iavarone, M.1    Trabut, J.B.2    Delpuech, O.3    Carnot, F.4    Colombo, M.5
  • 13
    • 52649139395 scopus 로고    scopus 로고
    • COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis
    • Ma NF, Lau SH, Hu L, Xie D, Wu J, et al. (2008) COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis. Clin Cancer Res 14: 5061-5068.
    • (2008) Clin Cancer Res , vol.14 , pp. 5061-5068
    • Ma, N.F.1    Lau, S.H.2    Hu, L.3    Xie, D.4    Wu, J.5
  • 14
    • 37449003586 scopus 로고    scopus 로고
    • Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma
    • Xu R, Zhang X, Zhang W, Fang Y, Zheng S, et al. (2007) Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma. Hepatology 46: 1810-1820.
    • (2007) Hepatology , vol.46 , pp. 1810-1820
    • Xu, R.1    Zhang, X.2    Zhang, W.3    Fang, Y.4    Zheng, S.5
  • 15
    • 34249901562 scopus 로고    scopus 로고
    • RNA interference targeting HBx suppresses tumor growth and enhances cisplatin chemosensitivity in human hepatocellular carcinoma
    • Cheng AS, Wong N, Tse AM, Chan KY, Chan KK, et al. (2007) RNA interference targeting HBx suppresses tumor growth and enhances cisplatin chemosensitivity in human hepatocellular carcinoma. Cancer Lett 253: 43-52.
    • (2007) Cancer Lett , vol.253 , pp. 43-52
    • Cheng, A.S.1    Wong, N.2    Tse, A.M.3    Chan, K.Y.4    Chan, K.K.5
  • 16
    • 62549156668 scopus 로고    scopus 로고
    • Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6
    • Wang X, Wang HK, McCoy JP, Banerjee NS, Rader JS, et al. (2009) Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. RNA 15: 637-647.
    • (2009) RNA , vol.15 , pp. 637-647
    • Wang, X.1    Wang, H.K.2    McCoy, J.P.3    Banerjee, N.S.4    Rader, J.S.5
  • 17
    • 58049170793 scopus 로고    scopus 로고
    • MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes
    • Pichler K, Schneider G, Grassmann R, (2008) MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes. Retrovirology 5: 100.
    • (2008) Retrovirology , vol.5 , pp. 100
    • Pichler, K.1    Schneider, G.2    Grassmann, R.3
  • 18
    • 38849160013 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways
    • Cameron JE, Yin Q, Fewell C, Lacey M, McBride J, et al. (2008) Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways. J Virol 82: 1946-1958.
    • (2008) J Virol , vol.82 , pp. 1946-1958
    • Cameron, J.E.1    Yin, Q.2    Fewell, C.3    Lacey, M.4    McBride, J.5
  • 19
    • 77953574309 scopus 로고    scopus 로고
    • Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3
    • Wang Y, Lu Y, Toh ST, Sung WK, Tan P, et al. (2010) Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3. J Hepatol 53: 57-66.
    • (2010) J Hepatol , vol.53 , pp. 57-66
    • Wang, Y.1    Lu, Y.2    Toh, S.T.3    Sung, W.K.4    Tan, P.5
  • 20
    • 0033960043 scopus 로고    scopus 로고
    • A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice
    • Brown JJ, Parashar B, Moshage H, Tanaka KE, Engelhardt D, et al. (2000) A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice. Hepatology 31: 173-181.
    • (2000) Hepatology , vol.31 , pp. 173-181
    • Brown, J.J.1    Parashar, B.2    Moshage, H.3    Tanaka, K.E.4    Engelhardt, D.5
  • 21
    • 77950600868 scopus 로고    scopus 로고
    • Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells
    • Cheng B, Zheng Y, Guo X, Wang Y, Liu C, (2010) Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells. Liver Int 30: 319-326.
    • (2010) Liver Int , vol.30 , pp. 319-326
    • Cheng, B.1    Zheng, Y.2    Guo, X.3    Wang, Y.4    Liu, C.5
  • 22
    • 41149091600 scopus 로고    scopus 로고
    • Genotype-specific genomic markers associated with primary hepatomas, based on complete genomic sequencing of hepatitis B virus
    • Sung JJ, Tsui SK, Tse CH, Ng EY, Leung KS, et al. (2008) Genotype-specific genomic markers associated with primary hepatomas, based on complete genomic sequencing of hepatitis B virus. J Virol 82: 3604-3611.
    • (2008) J Virol , vol.82 , pp. 3604-3611
    • Sung, J.J.1    Tsui, S.K.2    Tse, C.H.3    Ng, E.Y.4    Leung, K.S.5
  • 23
    • 0025669868 scopus 로고
    • Correlation of tissue-specific methylation with gene inactivity in hepatitis B virus transgenic mice
    • Araki K, Akagi K, Miyazaki J, Matsubara K, Yamamura K, (1990) Correlation of tissue-specific methylation with gene inactivity in hepatitis B virus transgenic mice. Jpn J Cancer Res 81: 1265-1271.
    • (1990) Jpn J Cancer Res , vol.81 , pp. 1265-1271
    • Araki, K.1    Akagi, K.2    Miyazaki, J.3    Matsubara, K.4    Yamamura, K.5
  • 24
    • 34547487035 scopus 로고    scopus 로고
    • Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin
    • Chen Y, Lin MC, Yao H, Wang H, Zhang AQ, et al. (2007) Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. Hepatology 46: 200-208.
    • (2007) Hepatology , vol.46 , pp. 200-208
    • Chen, Y.1    Lin, M.C.2    Yao, H.3    Wang, H.4    Zhang, A.Q.5
  • 25
    • 31544465230 scopus 로고    scopus 로고
    • Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters
    • Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, et al. (2006) Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. Mol Cell 21: 393-404.
    • (2006) Mol Cell , vol.21 , pp. 393-404
    • Cheng, A.S.1    Jin, V.X.2    Fan, M.3    Smith, L.T.4    Liyanarachchi, S.5
  • 26
    • 70350724544 scopus 로고    scopus 로고
    • Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22
    • Lung RW, Tong JH, Sung YM, Leung PS, Ng DC, et al. (2009) Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22. Neoplasia 11: 1174-1184.
    • (2009) Neoplasia , vol.11 , pp. 1174-1184
    • Lung, R.W.1    Tong, J.H.2    Sung, Y.M.3    Leung, P.S.4    Ng, D.C.5
  • 27
    • 0025907983 scopus 로고
    • HBx gene of hepatitis B virus induces liver cancer in transgenic mice
    • Kim CM, Koike K, Saito I, Miyamura T, Jay G, (1991) HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 351: 317-320.
    • (1991) Nature , vol.351 , pp. 317-320
    • Kim, C.M.1    Koike, K.2    Saito, I.3    Miyamura, T.4    Jay, G.5
  • 28
    • 4644219526 scopus 로고    scopus 로고
    • Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma
    • Chan HL, Hui AY, Wong ML, Tse AM, Hung LC, et al. (2004) Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma. Gut 53: 1494-1498.
    • (2004) Gut , vol.53 , pp. 1494-1498
    • Chan, H.L.1    Hui, A.Y.2    Wong, M.L.3    Tse, A.M.4    Hung, L.C.5
  • 29
    • 38349094747 scopus 로고    scopus 로고
    • High viral load and hepatitis B virus subgenotype ce are associated with increased risk of hepatocellular carcinoma
    • Chan HL, Tse CH, Mo F, Koh J, Wong VW, et al. (2008) High viral load and hepatitis B virus subgenotype ce are associated with increased risk of hepatocellular carcinoma. J Clin Oncol 26: 177-182.
    • (2008) J Clin Oncol , vol.26 , pp. 177-182
    • Chan, H.L.1    Tse, C.H.2    Mo, F.3    Koh, J.4    Wong, V.W.5
  • 30
    • 78651411120 scopus 로고    scopus 로고
    • MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2
    • Lu J, He ML, Wang L, Chen Y, Liu X, et al. (2011) MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res 71: 225-233.
    • (2011) Cancer Res , vol.71 , pp. 225-233
    • Lu, J.1    He, M.L.2    Wang, L.3    Chen, Y.4    Liu, X.5
  • 31
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, et al. (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137: 1005-1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3    Wentzel, E.A.4    Montgomery, C.L.5
  • 32
    • 76749165688 scopus 로고    scopus 로고
    • MiRNA-26b regulates the expression of cyclooxygenase-2 in desferrioxamine-treated CNE cells
    • Ji Y, He Y, Liu L, Zhong X, (2010) MiRNA-26b regulates the expression of cyclooxygenase-2 in desferrioxamine-treated CNE cells. FEBS Lett 584: 961-967.
    • (2010) FEBS Lett , vol.584 , pp. 961-967
    • Ji, Y.1    He, Y.2    Liu, L.3    Zhong, X.4
  • 33
    • 79952308806 scopus 로고    scopus 로고
    • Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b
    • In press
    • Ma YL, Zhang P, Wang F, Moyer MP, Yang JJ, et al. (2010) Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b. J Cell Mol Med In press.
    • (2010) J Cell Mol Med
    • Ma, Y.L.1    Zhang, P.2    Wang, F.3    Moyer, M.P.4    Yang, J.J.5
  • 34
    • 77950602604 scopus 로고    scopus 로고
    • Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    • Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, et al. (2010) Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 51: 836-845.
    • (2010) Hepatology , vol.51 , pp. 836-845
    • Xiong, Y.1    Fang, J.H.2    Yun, J.P.3    Yang, J.4    Zhang, Y.5
  • 35
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, et al. (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 104: 15805-15810.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15805-15810
    • Fabbri, M.1    Garzon, R.2    Cimmino, A.3    Liu, Z.4    Zanesi, N.5
  • 36
    • 39149134593 scopus 로고    scopus 로고
    • Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis
    • Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, et al. (2008) Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis. Leukemia 22: 330-338.
    • (2008) Leukemia , vol.22 , pp. 330-338
    • Marton, S.1    Garcia, M.R.2    Robello, C.3    Persson, H.4    Trajtenberg, F.5
  • 37
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, et al. (2011) Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 30: 843-853.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3    Chen, W.4    Callander, N.S.5
  • 38
    • 40449131878 scopus 로고    scopus 로고
    • Loss of mir-146a function in hormone-refractory prostate cancer
    • Lin SL, Chiang A, Chang D, Ying SY, (2008) Loss of mir-146a function in hormone-refractory prostate cancer. RNA 14: 417-424.
    • (2008) RNA , vol.14 , pp. 417-424
    • Lin, S.L.1    Chiang, A.2    Chang, D.3    Ying, S.Y.4
  • 39
    • 76049113205 scopus 로고    scopus 로고
    • Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes
    • Braconi C, Valeri N, Gasparini P, Huang N, Taccioli C, et al. (2010) Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes. Clin Cancer Res 16: 957-966.
    • (2010) Clin Cancer Res , vol.16 , pp. 957-966
    • Braconi, C.1    Valeri, N.2    Gasparini, P.3    Huang, N.4    Taccioli, C.5
  • 40
    • 77957198921 scopus 로고    scopus 로고
    • MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells
    • Xu C, Liu S, Fu H, Li S, Tie Y, et al. (2010) MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells. Eur J Cancer 46: 2828-2836.
    • (2010) Eur J Cancer , vol.46 , pp. 2828-2836
    • Xu, C.1    Liu, S.2    Fu, H.3    Li, S.4    Tie, Y.5
  • 41
    • 70349168446 scopus 로고    scopus 로고
    • Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation
    • Huang X, Ding L, Bennewith KL, Tong RT, Welford SM, et al. (2009) Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Mol Cell 35: 856-867.
    • (2009) Mol Cell , vol.35 , pp. 856-867
    • Huang, X.1    Ding, L.2    Bennewith, K.L.3    Tong, R.T.4    Welford, S.M.5
  • 42
    • 78650944900 scopus 로고    scopus 로고
    • MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1)
    • Tsuchiya S, Fujiwara T, Sato F, Shimada Y, Tanaka E, et al. (2011) MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). J Biol Chem 286: 420-428.
    • (2011) J Biol Chem , vol.286 , pp. 420-428
    • Tsuchiya, S.1    Fujiwara, T.2    Sato, F.3    Shimada, Y.4    Tanaka, E.5
  • 43
    • 69249228684 scopus 로고    scopus 로고
    • Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts
    • Maes OC, Sarojini H, Wang E, (2009) Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts. J Cell Physiol 221: 109-119.
    • (2009) J Cell Physiol , vol.221 , pp. 109-119
    • Maes, O.C.1    Sarojini, H.2    Wang, E.3
  • 44
    • 62849115345 scopus 로고    scopus 로고
    • Subcellular mislocalization of mutant hepatitis B X proteins contributes to modulation of STAT/SOCS signaling in hepatocellular carcinoma
    • Bock CT, Toan NL, Koeberlein B, Song le H, Chin R, et al. (2008) Subcellular mislocalization of mutant hepatitis B X proteins contributes to modulation of STAT/SOCS signaling in hepatocellular carcinoma. Intervirology 51: 432-443.
    • (2008) Intervirology , vol.51 , pp. 432-443
    • Bock, C.T.1    Toan, N.L.2    Koeberlein, B.3    Song le, H.4    Chin, R.5
  • 45
    • 38949184246 scopus 로고    scopus 로고
    • Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival
    • Jiang J, Gusev Y, Aderca I, Mettler TA, Nagorney DM, et al. (2008) Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin Cancer Res 14: 419-427.
    • (2008) Clin Cancer Res , vol.14 , pp. 419-427
    • Jiang, J.1    Gusev, Y.2    Aderca, I.3    Mettler, T.A.4    Nagorney, D.M.5
  • 46
    • 50549084147 scopus 로고    scopus 로고
    • Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma
    • Li W, Xie L, He X, Li J, Tu K, et al. (2008) Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma. Int J Cancer 123: 1616-1622.
    • (2008) Int J Cancer , vol.123 , pp. 1616-1622
    • Li, W.1    Xie, L.2    He, X.3    Li, J.4    Tu, K.5
  • 47
    • 76049108572 scopus 로고    scopus 로고
    • MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling
    • Wong QW, Ching AK, Chan AW, Choy KW, To KF, et al. (2010) MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling. Clin Cancer Res 16: 867-875.
    • (2010) Clin Cancer Res , vol.16 , pp. 867-875
    • Wong, Q.W.1    Ching, A.K.2    Chan, A.W.3    Choy, K.W.4    To, K.F.5
  • 48
    • 59149098054 scopus 로고    scopus 로고
    • MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
    • Su H, Yang JR, Xu T, Huang J, Xu L, et al. (2009) MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 69: 1135-1142.
    • (2009) Cancer Res , vol.69 , pp. 1135-1142
    • Su, H.1    Yang, J.R.2    Xu, T.3    Huang, J.4    Xu, L.5
  • 49
    • 46249125127 scopus 로고    scopus 로고
    • MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1
    • Wong QW, Lung RW, Law PT, Lai PB, Chan KY, et al. (2008) MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology 135: 257-269.
    • (2008) Gastroenterology , vol.135 , pp. 257-269
    • Wong, Q.W.1    Lung, R.W.2    Law, P.T.3    Lai, P.B.4    Chan, K.Y.5
  • 50
    • 65449154685 scopus 로고    scopus 로고
    • Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma
    • Ura S, Honda M, Yamashita T, Ueda T, Takatori H, et al. (2009) Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma. Hepatology 49: 1098-1112.
    • (2009) Hepatology , vol.49 , pp. 1098-1112
    • Ura, S.1    Honda, M.2    Yamashita, T.3    Ueda, T.4    Takatori, H.5
  • 51
    • 77952028244 scopus 로고    scopus 로고
    • MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma
    • Chen J, Feilotter HE, Pare GC, Zhang X, Pemberton JG, et al. (2010) MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma. Am J Pathol 176: 2520-2529.
    • (2010) Am J Pathol , vol.176 , pp. 2520-2529
    • Chen, J.1    Feilotter, H.E.2    Pare, G.C.3    Zhang, X.4    Pemberton, J.G.5
  • 52
    • 70449124422 scopus 로고    scopus 로고
    • Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
    • Li XF, Yan PJ, Shao ZM, (2009) Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. Oncogene 28: 3937-3948.
    • (2009) Oncogene , vol.28 , pp. 3937-3948
    • Li, X.F.1    Yan, P.J.2    Shao, Z.M.3
  • 53
    • 77955590791 scopus 로고    scopus 로고
    • miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer
    • Rauhala HE, Jalava SE, Isotalo J, Bracken H, Lehmusvaara S, et al. (2010) miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer. Int J Cancer 127: 1363-1372.
    • (2010) Int J Cancer , vol.127 , pp. 1363-1372
    • Rauhala, H.E.1    Jalava, S.E.2    Isotalo, J.3    Bracken, H.4    Lehmusvaara, S.5
  • 54
    • 0030787584 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha
    • Su F, Schneider RJ, (1997) Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha. Proc Natl Acad Sci USA 94: 8744-8749.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8744-8749
    • Su, F.1    Schneider, R.J.2
  • 55
    • 25844447771 scopus 로고    scopus 로고
    • The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage
    • Lee AT, Ren J, Wong ET, Ban KH, Lee LA, et al. (2005) The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage. J Biol Chem 280: 33525-33535.
    • (2005) J Biol Chem , vol.280 , pp. 33525-33535
    • Lee, A.T.1    Ren, J.2    Wong, E.T.3    Ban, K.H.4    Lee, L.A.5
  • 56
    • 34548306767 scopus 로고    scopus 로고
    • X protein of hepatitis B virus functions as a transcriptional corepressor on the human telomerase promoter
    • Su JM, Lai XM, Lan KH, Li CP, Chao Y, et al. (2007) X protein of hepatitis B virus functions as a transcriptional corepressor on the human telomerase promoter. Hepatology 46: 402-413.
    • (2007) Hepatology , vol.46 , pp. 402-413
    • Su, J.M.1    Lai, X.M.2    Lan, K.H.3    Li, C.P.4    Chao, Y.5
  • 57
    • 33745146547 scopus 로고    scopus 로고
    • Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells
    • Han J, Ding L, Yuan B, Yang X, Wang X, et al. (2006) Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells. Nucleic Acids Res 34: 3095-3106.
    • (2006) Nucleic Acids Res , vol.34 , pp. 3095-3106
    • Han, J.1    Ding, L.2    Yuan, B.3    Yang, X.4    Wang, X.5
  • 58
    • 69249110047 scopus 로고    scopus 로고
    • Deregulated direct targets of the hepatitis B virus (HBV) protein, HBx, identified through chromatin immunoprecipitation and expression microarray profiling
    • Sung WK, Lu Y, Lee CW, Zhang D, Ronaghi M, et al. (2009) Deregulated direct targets of the hepatitis B virus (HBV) protein, HBx, identified through chromatin immunoprecipitation and expression microarray profiling. J Biol Chem 284: 21941-21954.
    • (2009) J Biol Chem , vol.284 , pp. 21941-21954
    • Sung, W.K.1    Lu, Y.2    Lee, C.W.3    Zhang, D.4    Ronaghi, M.5
  • 59
    • 77957954445 scopus 로고    scopus 로고
    • Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development
    • Xu H, He JH, Xiao ZD, Zhang QQ, Chen YQ, et al. (2010) Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology 52: 1431-1442.
    • (2010) Hepatology , vol.52 , pp. 1431-1442
    • Xu, H.1    He, J.H.2    Xiao, Z.D.3    Zhang, Q.Q.4    Chen, Y.Q.5
  • 60
    • 61349112251 scopus 로고    scopus 로고
    • MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
    • Sander S, Bullinger L, Klapproth K, Fiedler K, Kestler HA, et al. (2008) MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 112: 4202-4212.
    • (2008) Blood , vol.112 , pp. 4202-4212
    • Sander, S.1    Bullinger, L.2    Klapproth, K.3    Fiedler, K.4    Kestler, H.A.5
  • 61
    • 78650412626 scopus 로고    scopus 로고
    • Epigenetic regulation of signaling pathways in cancer: role of the histone methyltransferase EZH2
    • Tsang DP, Cheng AS, (2011) Epigenetic regulation of signaling pathways in cancer: role of the histone methyltransferase EZH2. J Gastroenterol Hepatol 26: 19-27.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 19-27
    • Tsang, D.P.1    Cheng, A.S.2
  • 62
    • 79957912993 scopus 로고    scopus 로고
    • EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis
    • Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, et al. (2011) EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis. Cancer Res 71: 4028-4039.
    • (2011) Cancer Res , vol.71 , pp. 4028-4039
    • Cheng, A.S.1    Lau, S.S.2    Chen, Y.3    Kondo, Y.4    Li, M.S.5
  • 63
    • 44649179545 scopus 로고    scopus 로고
    • MicroRNAs and cancer epigenetics
    • Fabbri M, (2008) MicroRNAs and cancer epigenetics. Curr Opin Investig Drugs 9: 583-590.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 583-590
    • Fabbri, M.1
  • 64
    • 70349871321 scopus 로고    scopus 로고
    • MicroRNA expression, survival, and response to interferon in liver cancer
    • Ji J, Shi J, Budhu A, Yu Z, Forgues M, et al. (2009) MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med 361: 1437-1447.
    • (2009) N Engl J Med , vol.361 , pp. 1437-1447
    • Ji, J.1    Shi, J.2    Budhu, A.3    Yu, Z.4    Forgues, M.5
  • 65
    • 54549119169 scopus 로고    scopus 로고
    • NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma
    • Wang H, Garzon R, Sun H, Ladner KJ, Singh R, et al. (2008) NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell 14: 369-381.
    • (2008) Cancer Cell , vol.14 , pp. 369-381
    • Wang, H.1    Garzon, R.2    Sun, H.3    Ladner, K.J.4    Singh, R.5
  • 67
    • 60549090858 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
    • Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS, et al. (2009) Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res 69: 1279-1283.
    • (2009) Cancer Res , vol.69 , pp. 1279-1283
    • Hurst, D.R.1    Edmonds, M.D.2    Scott, G.K.3    Benz, C.C.4    Vaidya, K.S.5
  • 68
    • 44449111693 scopus 로고    scopus 로고
    • MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins
    • Sengupta S, den Boon JA, Chen IH, Newton MA, Stanhope SA, et al. (2008) MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A 105: 5874-5878.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5874-5878
    • Sengupta, S.1    den Boon, J.A.2    Chen, I.H.3    Newton, M.A.4    Stanhope, S.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.