Measuring autoantibodies against IL-17F and IL-22 in autoimmune polyendocrine syndrome type I by radioligand binding assay using fusion proteins

Scandinavian Journal of Immunology

Volumn 74, Issue 3, 2011, Pages 327-333

  Oftedal, B E V ^a,b   Kampe O ^c   Meager, A ^d   Ahlgren, K M ^c   Lobell, A ^c   Husebye, E S ^a,b   Wolff, A S B ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c UPPSALA UNIVERSITY   (Sweden)

^d NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DIMER; HETERODIMER; HOMODIMER; HYBRID PROTEIN; INTERLEUKIN 17F; INTERLEUKIN 22; MONOMER; RADIOLIGAND;

ADULT; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; BINDING ASSAY; CLINICAL ARTICLE; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; MUCOCUTANEOUS CANDIDIASIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SCREENING TEST; SENSITIVITY AND SPECIFICITY; STANDARDIZATION;

ADULT; AUTOANTIBODIES; CANDIDIASIS, CHRONIC MUCOCUTANEOUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTERLEUKIN-17; INTERLEUKINS; MALE; NORWAY; POLYENDOCRINOPATHIES, AUTOIMMUNE; PROTEIN MULTIMERIZATION; RADIOLIGAND ASSAY; RECOMBINANT FUSION PROTEINS; SENSITIVITY AND SPECIFICITY;

EID: 79961124370     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2011.02573.x     Document Type: Article

References (29)

1. Alimohammadi M, Björklund P, Hallgren A et al. Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. N Engl J Med 2008;358:1018-28.
2. Ahonen P, Myllarniemi S, Sipila I, Perheentupa J. Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med 1990;322:1829-36.
3. Husebye ES, Perheentupa J, Rautemaa R, Kämpe O. Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I. J Intern Med 2009;265:514-29.
4. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat Genet 1997;17:399-403.
5. Nagamine K, Peterson P, Scott HS et al. Positional cloning of the APECED gene. Nat Genet 1997;17:393-8.
6. Wolff AS, Erichsen MM, Meager A et al. Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. J Clin Endocrinol Metab 2007;92:595-603.
7. Abramson J, Giraud M, Benoist C, Mathis D. Aire's partners in the molecular control of immunological tolerance. Cell 2010;140:123-35.
8. Derbinski J, Schulte A, Kyewski B, Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001;2:1032-9.
9. Gibson TJ, Ramu C, Gemund C, Aasland R. The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor. Trends Biochem Sci 1998;23:242-4.
10. Heino M, Peterson P, Kudoh J et al. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun 1999;257:821-5.
11. Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Holländer GA. Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol 2000;165:1976-83.
12. Koh AS, Kuo AJ, Park SY et al. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc Natl Acad Sci U S A 2008;105:15878-83.
13. Kisand K, Boe Wolff AS, Podkrajsek KT et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med 2010;207:299-308.
14. Puel A, Doffinger R, Natividad A et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med 2010;207:291-7.
15. Hymowitz SG, Filvaroff EH, Yin JP et al. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J 2001;20:5332-41.
16. Onishi RM, Gaffen SL. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology 2010;129:311-21.
17. Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity 2004;21:241-54.
18. Wright JF, Guo Y, Quazi A et al. Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells. J Biol Chem 2007;282:13447-55.
19. de Oliveira Neto M, Ferreira JR Jr, Colau D et al. Interleukin-22 forms dimers that are recognized by two interleukin-22R1 receptor chains. Biophys J 2008;94:1754-65.
20. Eyerich K, Foerster S, Rombold S et al. Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22. J Invest Dermatol 2008;128:2640-5.
21. Puel A, Cypowyj S, Bustamante J et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 2011;332:65-8.
22. Ahlgren KM, Moretti S, Lundgren BA et al. Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model. Eur J Immunol 2011;41:235-45.
23. Husebye ES, Gebre-Medhin G, Tuomi T et al. Autoantibodies against aromatic L-amino acid decarboxylase in autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab 1997;82:147-50.
24. Cheng Y, Patel DJ. An efficient system for small protein expression and refolding. Biochem Biophys Res Commun 2004;317:401-5.
25. Torn C, Mueller PW, Schlosser M, Bonifacio E, Bingley PJ. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2. Diabetologia 2008;51:846-52.
26. Persson A, Becker C, Hansson I, Nilsson A, Torn C. Comparison of measurements of autoantibodies to glutamic acid decarboxylase and islet antigen-2 in whole blood eluates from dried blood spots using the RSR-enzyme linked immunosorbent assay kits and in-house radioimmunoassays. Exp Diabetes Res 2010;2010:173652.
27. Perheentupa J. Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Clin Endocrinol Metab 2006;91:2843-50.
28. Zlotogora J, Shapiro MS. Polyglandular autoimmune syndrome type I among Iranian Jews. J Med Genet 1992;29:824-6.
29. Oftedal BE, Wolff AS, Bratland E et al. Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clin Immunol 2008;129:163-9.