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Volumn 301, Issue 2, 2011, Pages

Trapping of BMP receptors in distinct membrane domains inhibits their function in pulmonary arterial hypertension

Author keywords

Bone morphogenic protein receptors; Colocalization; Mutants; Smad signaling

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CLATHRIN; SMAD PROTEIN;

EID: 79961092518     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00300.2010     Document Type: Article
Times cited : (14)

References (37)
  • 2
    • 0033526067 scopus 로고    scopus 로고
    • Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
    • Bhatia M, Bonnet D, Wu D, Murdoch B, Wrana J, Gallacher L, Dick JE. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med 189: 1139-1148, 1999.
    • (1999) J Exp Med , vol.189 , pp. 1139-1148
    • Bhatia, M.1    Bonnet, D.2    Wu, D.3    Murdoch, B.4    Wrana, J.5    Gallacher, L.6    Dick, J.E.7
  • 3
    • 70349590581 scopus 로고    scopus 로고
    • FRET reveals novel protein-receptor interaction of bone morphogenetic proteins receptors and adaptor protein 2 at the cell surface
    • Bragdon B, Thinakaran S, Bonor J, Underhill TM, Petersen NO, Nohe A. FRET reveals novel protein-receptor interaction of bone morphogenetic proteins receptors and adaptor protein 2 at the cell surface. Biophys J 97: 1428-1435, 2009.
    • (2009) Biophys J , vol.97 , pp. 1428-1435
    • Bragdon, B.1    Thinakaran, S.2    Bonor, J.3    Underhill, T.M.4    Petersen, N.O.5    Nohe, A.6
  • 4
    • 0031883792 scopus 로고    scopus 로고
    • An image correlation analysis of the distribution of clathrin associated adaptor protein (AP-2) at the plasma membrane
    • Brown CM, Petersen NO. An image correlation analysis of the distribution of clathrin associated adaptor protein (AP-2) at the plasma membrane. J Cell Sci 111: 271-281, 1998.
    • (1998) J Cell Sci , vol.111 , pp. 271-281
    • Brown, C.M.1    Petersen, N.O.2
  • 5
    • 0035721752 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
    • Caestecker MD, Meyrick B. Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension. Respir Res 2: 193-197, 2001.
    • (2001) Respir Res , vol.2 , pp. 193-197
    • Caestecker, M.D.1    Meyrick, B.2
  • 6
    • 0025672641 scopus 로고
    • Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone
    • Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA, Wozney JM. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87: 9843-9847, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazzi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5    Wang, E.A.6    Wozney, J.M.7
  • 8
    • 0035854367 scopus 로고    scopus 로고
    • Endocytosis and signaling: An inseparable partnership
    • Di Fiore PP, De Camilli P. Endocytosis and signaling: an inseparable partnership. Cell 106: 1-4, 2001.
    • (2001) Cell , vol.106 , pp. 1-4
    • di Fiore, P.P.1    de Camilli, P.2
  • 9
    • 0035490884 scopus 로고    scopus 로고
    • The endocytosis pathway: A mosaic of domains
    • Gruenberg J. The endocytosis pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2: 721-730, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 721-730
    • Gruenberg, J.1
  • 11
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BL. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10: 1580-1594, 1996.
    • (1996) Genes Dev , vol.10 , pp. 1580-1594
    • Hogan, B.L.1
  • 13
    • 0032516862 scopus 로고    scopus 로고
    • Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer
    • Jonk LJC, Itoh S, Heldin CH, ten Dijke P, Kruijer W. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer. J Biol Chem 273: 21145- 21142, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 21142-21145
    • Jonk, L.J.C.1    Itoh, S.2    Heldin, C.H.3    ten Dijke, P.4    Kruijer, W.5
  • 14
    • 0030773834 scopus 로고    scopus 로고
    • Opposing BMP and EGF signaling pathways coverage on the TGF-β family mediator Smad1
    • Kretzschmar M, Doody J, Massague J. Opposing BMP and EGF signaling pathways coverage on the TGF-β family mediator Smad1. Nature 389: 618-622, 1997.
    • (1997) Nature , vol.389 , pp. 618-622
    • Kretzschmar, M.1    Doody, J.2    Massague, J.3
  • 18
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massague J. TGF-β signal transduction. Annu Rev Biochem 67: 753-791, 1998.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massague, J.1
  • 19
    • 44349101103 scopus 로고    scopus 로고
    • Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signaling in pulmonary arterial hypertension
    • Nasim AT, Ghouri A, Patel James V, Rudarakanchana N B, Morrell NW, Trembath RC. Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signaling in pulmonary arterial hypertension. Hum Mol Genet 17: 1683-1694, 2008.
    • (2008) Hum Mol Genet , vol.17 , pp. 1683-1694
    • Nasim, A.T.1    Ghouri, A.2    Patel James, V.3    Rudarakanchana, N.B.4    Morrell, N.W.5    Trembath, R.C.6
  • 20
    • 0036735752 scopus 로고    scopus 로고
    • Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension
    • Nishihara A, Watabe T, Imamura T, Miyazono K. Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension. Mol Biol Cell 13: 3055-3063, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 3055-3063
    • Nishihara, A.1    Watabe, T.2    Imamura, T.3    Miyazono, K.4
  • 21
    • 0037085287 scopus 로고    scopus 로고
    • The mode of bone morphogenetic protein (BMP) receptor oligomer- ization determines different BMP-2 signaling pathways
    • Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis Y, Knaus P. The mode of bone morphogenetic protein (BMP) receptor oligomer- ization determines different BMP-2 signaling pathways. J Biol Chem 277: 5330-5338, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 5330-5338
    • Nohe, A.1    Hassel, S.2    Ehrlich, M.3    Neubauer, F.4    Sebald, W.5    Henis, Y.6    Knaus, P.7
  • 22
    • 0346996450 scopus 로고    scopus 로고
    • Signal transduction of bone morphogenetic protein receptors
    • Nohe A, Keating E, Knaus P, Petersen NO. Signal transduction of bone morphogenetic protein receptors. Cell Signal 16: 291-299, 2004.
    • (2004) Cell Signal , vol.16 , pp. 291-299
    • Nohe, A.1    Keating, E.2    Knaus, P.3    Petersen, N.O.4
  • 23
    • 1642388432 scopus 로고    scopus 로고
    • Caveolin-1 isoform reorganization studied by image correlation spectroscopy
    • Nohe A, Keating E, Loh C, Underhill MT, Petersen NO. Caveolin-1 isoform reorganization studied by image correlation spectroscopy. Faraday Discuss 126: 185-195, 2004.
    • (2004) Faraday Discuss , vol.126 , pp. 185-195
    • Nohe, A.1    Keating, E.2    Loh, C.3    Underhill, M.T.4    Petersen, N.O.5
  • 24
    • 0041885046 scopus 로고    scopus 로고
    • Effect of the distribution and clustering of the type IA BMP receptor (ALK3) with the type II BMP receptor on the activation of signaling pathways
    • Nohe A, Keating E, Underhill T, Knaus P, Petersen NO. Effect of the distribution and clustering of the type IA BMP receptor (ALK3) with the type II BMP receptor on the activation of signaling pathways. J Cell Sci 116: 3277-3284, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 3277-3284
    • Nohe, A.1    Keating, E.2    Underhill, T.3    Knaus, P.4    Petersen, N.O.5
  • 25
    • 14644396524 scopus 로고    scopus 로고
    • Dynamics and interaction of caveolin-1 isoforms with BMP-receptors
    • Nohe A, Keating E, Underhill T, Knaus P, Petersen NO. Dynamics and interaction of caveolin-1 isoforms with BMP-receptors. J Cell Sci 118: 643-650, 2005.
    • (2005) J Cell Sci , vol.118 , pp. 643-650
    • Nohe, A.1    Keating, E.2    Underhill, T.3    Knaus, P.4    Petersen, N.O.5
  • 26
    • 0027217936 scopus 로고
    • Quantitation of membrane receptor distributions by image correlation spectroscopy: Concept and application
    • Petersen NO, Hoddelius PL, Wiseman PW, Seger O, Magnusson K. Quantitation of membrane receptor distributions by image correlation spectroscopy: concept and application. Biophys J 65: 1135-1146, 1993.
    • (1993) Biophys J , vol.65 , pp. 1135-1146
    • Petersen, N.O.1    Hoddelius, P.L.2    Wiseman, P.W.3    Seger, O.4    Magnusson, K.5
  • 27
    • 0035817629 scopus 로고    scopus 로고
    • Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways
    • Puri V, Watanabe R, Singh RD, Dominguez M, Brown JC, Wheatley CL, Mark DL, Pagano RE. Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways. J Cell Biol 154: 535-547, 2001.
    • (2001) J Cell Biol , vol.154 , pp. 535-547
    • Puri, V.1    Watanabe, R.2    Singh, R.D.3    Dominguez, M.4    Brown, J.C.5    Wheatley, C.L.6    Mark, D.L.7    Pagano, R.E.8
  • 29
    • 0031031440 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Rubin LJ. Primary pulmonary hypertension. N Engl J Med 336: 111-117, 1997.
    • (1997) N Engl J Med , vol.336 , pp. 111-117
    • Rubin, L.J.1
  • 31
    • 0034778362 scopus 로고    scopus 로고
    • New insights into the pathogenesis and treatment of primary pulmonary hypertension
    • Rudarakanchana N, Trembath RC, Morrell NW. New insights into the pathogenesis and treatment of primary pulmonary hypertension. Thorax 56: 888-890, 2001.
    • (2001) Thorax , vol.56 , pp. 888-890
    • Rudarakanchana, N.1    Trembath, R.C.2    Morrell, N.W.3
  • 33
    • 0031795289 scopus 로고    scopus 로고
    • Diffusion of transferrin receptor clusters
    • Srivastava M, Petersen NO. Diffusion of transferrin receptor clusters. Biophys Chem 75: 201-211, 1998.
    • (1998) Biophys Chem , vol.75 , pp. 201-211
    • Srivastava, M.1    Petersen, N.O.2
  • 35
    • 0027520440 scopus 로고
    • Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
    • Wang LH, Rothberg KG, Anderson RGW. Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol 123: 1007-1117, 1993.
    • (1993) J Cell Biol , vol.123 , pp. 1007-1117
    • Wang, L.H.1    Rothberg, K.G.2    Anderson, R.G.W.3
  • 36
    • 0343035665 scopus 로고    scopus 로고
    • Aggregation of PDGF-β receptors in human skin fibroblasts: Characterization by image correlation spectroscopy (ICS)
    • Wiseman PW, Höddelius P, Petersen NO, Magnusson K. Aggregation of PDGF-β receptors in human skin fibroblasts: characterization by image correlation spectroscopy (ICS). FEBS Lett 401: 43-48, 1997.
    • (1997) FEBS Lett , vol.401 , pp. 43-48
    • Wiseman, P.W.1    Höddelius, P.2    Petersen, N.O.3    Magnusson, K.4
  • 37
    • 0033027026 scopus 로고    scopus 로고
    • Image correlation spectroscopy. II. Optimization for ultrasensitive detection of preexisting platelet-derived growth factor-β receptor oligomers on intact cells
    • Wiseman PW, Petersen NO. Image correlation spectroscopy. II. Optimization for ultrasensitive detection of preexisting platelet-derived growth factor-β receptor oligomers on intact cells. Biophys J 76: 963-977, 1999.
    • (1999) Biophys J , vol.76 , pp. 963-977
    • Wiseman, P.W.1    Petersen, N.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.