메뉴 건너뛰기




Volumn 6, Issue 6, 2011, Pages 648-657

Probing elongating and branching β-D-galactosyltransferase activities in Leishmania parasites by making use of synthetic phosphoglycans

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEXTRO GALACTOSYLTRANSFERASE; BETA GALACTOSIDASE; ESTER DERIVATIVE; GALACTOSYLTRANSFERASE; LIPOPHOSPHOGLYCAN; OLIGOSACCHARIDE; PHOSPHODIESTER; TRITIUM; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE;

EID: 79961087840     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100416j     Document Type: Conference Paper
Times cited : (6)

References (40)
  • 1
    • 0036319712 scopus 로고    scopus 로고
    • Visceral leishmaniasis: Current status of control, diagnosis, and treatment, and a proposed research and development agenda
    • DOI 10.1016/S1473-3099(02)00347-X
    • Guerin, P. J., Olliaro, P., Sundar, S., Boelaert, M., Croft, S. L., Desjeux, P., Wasunna, M. K., and Bryceson, A. D. M. (2002) Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. Lancet Infect. Dis. 2, 494-501. (Pubitemid 34826855)
    • (2002) Lancet Infectious Diseases , vol.2 , Issue.8 , pp. 494-501
    • Guerin, P.J.1    Olliaro, P.2    Sundar, S.3    Boelaert, M.4    Croft, S.L.5    Desjeux, P.6    Wasunna, M.K.7    Bryceson, A.D.M.8
  • 2
    • 0037442697 scopus 로고    scopus 로고
    • Leishmaniasis: New approaches to disease control
    • Davies, C. R., Paul, K., Croft, S. L., and Sundar, S. (2003) Leishmaniasis: New approaches to disease control. BMJ [Br. Med. J.] 326, 377-382. (Pubitemid 36241477)
    • (2003) British Medical Journal , vol.326 , Issue.7385 , pp. 377-382
    • Davies, C.R.1    Kaye, P.2    Croft, S.L.3    Sundar, S.4
  • 3
    • 33846121304 scopus 로고    scopus 로고
    • HIV-1 replication is stimulated by sodium stibogluconate, the therapeutic mainstay in the treatment of leishmaniasis
    • DOI 10.1086/510398
    • Barat, C., Zhao, C., Ouellette, M., and Tremblay, M. J. (2007) HIV-1 replication is stimulated by sodium stibogluconate, the therapeutic mainstay in the treatment of leishmaniasis. J. Infect. Dis. 195, 236-245. (Pubitemid 46080056)
    • (2007) Journal of Infectious Diseases , vol.195 , Issue.2 , pp. 236-245
    • Barat, C.1    Zhao, C.2    Ouellette, M.3    Tremblay, M.J.4
  • 6
    • 33646700031 scopus 로고    scopus 로고
    • New world cutaneous leishmaniasis in travellers
    • DOI 10.1016/S1473-3099(06)70492-3, PII S1473309906704923
    • Schwartz, E., Hatz, Cr., and Blum, J. (2006) New world cutaneous leishmaniasis in travellers. Lancet Infect. Dis. 6, 342-349. (Pubitemid 43737272)
    • (2006) Lancet Infectious Diseases , vol.6 , Issue.6 , pp. 342-349
    • Schwartz, E.1    Hatz, C.2    Blum, J.3
  • 7
    • 0027257177 scopus 로고
    • The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes
    • McConville, M. J., and Ferguson, M. A. J. (1993) The structure, biosynthesis and functions of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukariotes. Biochem. J. 294, 305-324. (Pubitemid 23268825)
    • (1993) Biochemical Journal , vol.294 , Issue.2 , pp. 305-324
    • McConville, M.J.1    Ferguson, M.A.J.2
  • 8
    • 0034959183 scopus 로고    scopus 로고
    • Glycoconjugate structures of parasitic protozoa
    • Guha-Niyogi, A., Sullivan, D. R., and Turco, S. J. (2001) Glycoconjugate structures of parasitic protozoa. Glycobiology 11, 45R-59R. (Pubitemid 32605649)
    • (2001) Glycobiology , vol.11 , Issue.4
    • Guha-Niyogi, A.1    Sullivan, D.R.2    Turco, S.J.3
  • 9
    • 0035003815 scopus 로고    scopus 로고
    • Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species
    • DOI 10.1016/S1471-4922(01)01895-5, PII S1471492201018955
    • Turco, S. J., Späth, G. F., and Beverley, S. M. (2001) Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species. Trends Parasitol. 17, 223-226. (Pubitemid 32422166)
    • (2001) Trends in Parasitology , vol.17 , Issue.5 , pp. 223-226
    • Turco, S.J.1    Spath, G.F.2    Beverley, S.M.3
  • 10
    • 0042322609 scopus 로고    scopus 로고
    • Persistence without pathology in phosphoglycan-deficient Leishmania major
    • DOI 10.1126/science.1087499
    • Späth, G. F., Lye, L.-F., Segawa, H., Sacks, D., Turco, S. J., and Beverley, S. M. (2003) Persistence without pathology in phosphoglycandeficient Leishmania major. Science 301, 1241-1243. (Pubitemid 37052214)
    • (2003) Science , vol.301 , Issue.5637 , pp. 1241-1243
    • Spath, G.F.1    Lye, L.-F.2    Segawa, H.3    Sacks, D.L.4    Turco, S.J.5    Beverley, S.M.6
  • 11
    • 3342875937 scopus 로고    scopus 로고
    • Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG
    • DOI 10.1038/nature02675
    • Rogers, M. E., Ilg, T., Nikolaev, A. V., Ferguson, M. A. J., and Bates, P. (2004) Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG. Nature 430, 463-467. (Pubitemid 38987909)
    • (2004) Nature , vol.430 , Issue.6998 , pp. 463-467
    • Rogers, M.E.1    Ilg, T.2    Nikolaev, A.V.3    Ferguson, M.A.J.4    Bates, P.A.5
  • 12
    • 77955536094 scopus 로고    scopus 로고
    • Structure, functions, and biosynthesis of glycoconjugates of Leishmania spp. cell surface
    • Moscow
    • Novozhilova, N. M., and Bovin, N. V. (2010) Structure, functions, and biosynthesis of glycoconjugates of Leishmania spp. cell surface. Biochemistry (Moscow) 75, 770-780.
    • (2010) Biochemistry , vol.75 , pp. 770-780
    • Novozhilova, N.M.1    Bovin, N.V.2
  • 17
    • 0027286397 scopus 로고
    • Molecular variation in Leishmania
    • Moody, S. F. (1993) Molecular variation in Leishmania. Acta Trop. 53, 185-204. (Pubitemid 23176383)
    • (1993) Acta Tropica , vol.53 , Issue.3-4 , pp. 185-204
    • Moody, S.F.1
  • 19
    • 0033520079 scopus 로고    scopus 로고
    • Intra-species and stage-specific polymorphisms in lipophosphoglycan structure control Leishmania donovani-sand fly interactions
    • Mahoney, A. B., Sacks, D. L., Saraiva, E., Modi, G., and Turco, S. J. (1999) Intra-species and stage-specific polymorphisms in lipophosphoglycan structure control Leishmania donovani-sand fly interactions. Biochemistry 38, 9813-9823.
    • (1999) Biochemistry , vol.38 , pp. 9813-9823
    • Mahoney, A.B.1    Sacks, D.L.2    Saraiva, E.3    Modi, G.4    Turco, S.J.5
  • 21
    • 0025770425 scopus 로고
    • Cell-free biosynthesis of lipophosphoglycan from Leishmania donovani
    • Carver, M. A., and Turco, S. J. (1991) Cell-free biosynthesis of lipophosphoglycan from Leishmania donovani. J. Biol. Chem. 266, 10974-10981.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10974-10981
    • Carver, M.A.1    Turco, S.J.2
  • 22
    • 0028576469 scopus 로고
    • Biosynthesis of lipophosphoglycan from Leishmania major: Characterization of (β1-3) - galactosyltransferase(s)
    • Ng, K., Handman, E., and Bacic, A. (1994) Biosynthesis of lipophosphoglycan from Leishmania major: characterization of (β1-3)- galactosyltransferase(s). Glycobiology 4, 845-853.
    • (1994) Glycobiology , vol.4 , pp. 845-853
    • Ng, K.1    Handman, E.2    Bacic, A.3
  • 23
    • 0029948482 scopus 로고    scopus 로고
    • Biosynthesis of lipophosphoglycan from Leishmania major: Solubilization and characterization of a (β1-3)-galactosyltransferase
    • Ng, K., Handman, E., and Bacic, A. (1996) Biosynthesis of lipophosphoglycan from Leishmania major: solubilisation and characterization of a (β1-3)-galactosyltransferase. Biochem. J. 317, 247-255. (Pubitemid 26238353)
    • (1996) Biochemical Journal , vol.317 , Issue.1 , pp. 247-255
    • Ng, K.1    Handman, E.2    Bacic, A.3
  • 24
    • 0038121032 scopus 로고    scopus 로고
    • Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions
    • DOI 10.1074/jbc.M301568200
    • Dobson, D. E., Scholtes, L. D., Valdez, K. E., Sullivan, D. R., Mengeling, B. J., Cilmi, S., Turco, S. J., and Beverley, S. M. (2003) Functional identification of galactosyltransferases (SCGs) required for species-specificmodifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions. J. Biol. Chem. 278, 15523-15531. (Pubitemid 36799659)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.18 , pp. 15523-15531
    • Dobson, D.E.1    Scholtes, L.D.2    Valdez, K.E.3    Sullivan, D.R.4    Mengeling, B.J.5    Cilmi, S.6    Turco, S.J.7    Beverley, S.M.8
  • 25
    • 0029664952 scopus 로고    scopus 로고
    • Deficiency in β1,3-galactosyltransferase of a Leishmania major lipophosphoglycan mutant adversely influences the Leishmania-sand fly interaction
    • DOI 10.1074/jbc.271.34.20573
    • Butcher, B. A., Turco, S. J., Hilty, B. A., Pimenta, P. F., Panunzio, M., and Sacks, D. L. (1996) Deficiency in β1,3-galactosyltransferase of a Leishmania major lipophosphoglycan mutant adversely influences the Leishmania-sand fly interaction. J. Biol. Chem. 271, 20573-20579. (Pubitemid 26281834)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.34 , pp. 20573-20579
    • Butcher, B.A.1    Turco, S.J.2    Hilty, B.A.3    Pimentai, P.F.4    Panunzio, M.5    Sacks, D.L.6
  • 26
    • 1542407031 scopus 로고    scopus 로고
    • Infectivity and attenuation of Leishmania donovani promastigotes II: Association of the loss of parasite infectivity with the terminal galactosylation of precursor acceptors present in virulent parasites by the developmentally regulated galactosyltransferase
    • DOI 10.1111/j.1365-3024.2003.00660.x
    • Bhaumik, S., Basu, R., Roy, S., and De, T. (2003) Infectivity and attenuation of Leishmania donovani promastigotes II: Association of the loss of parasite infectivity with the terminal galactosylation of precursor acceptors present in virulent parasites by the developmentally regulated galactosyltransferase. Parasite Immunol. 25, 517-520. (Pubitemid 38333813)
    • (2003) Parasite Immunology , vol.25 , Issue.10 , pp. 517-520
    • Bhaumik, S.1    Basu, R.2    Roy, S.3    De, T.4
  • 27
    • 0029833568 scopus 로고    scopus 로고
    • Synthetic phospho-oligosaccharide fragments of lipophosphoglycan as accepters for Leishmania major α-D-mannosylphosphate transferase
    • Brown, G. M., Millar, A. R., Masterson, C., Brimacombe, J. S., Nikolaev, A. V., and Ferguson, M. A. J. (1996) Synthetic phosphooligosaccharide fragments of lipophosphoglycan as acceptors for Leishmania major R-D-mannosylphosphate transferase. Eur. J. Biochem. 242, 410-416. (Pubitemid 26414247)
    • (1996) European Journal of Biochemistry , vol.242 , Issue.2 , pp. 410-416
    • Brown, G.M.1    Millar, A.R.2    Masterson, C.3    Brimacombe, J.S.4    Nikolaev, A.V.5    Ferguson, M.A.J.6
  • 28
    • 0034636834 scopus 로고    scopus 로고
    • Characterization of the elongating α-D-mannosyl phosphate transferase from three species of Leishmania using synthetic acceptor substrate analogues
    • DOI 10.1021/bi000371s
    • Routier, F. H., Higson, A. P., Ivanova, I. A., Ross, A. J., Tsvetkov, Y. E., Yahunsky, D. V., Bates, P. A., Nikolaev, A. V., and Ferguson, M. A. J. (2000) Characterization of the elongating R-D-mannosyl phosphate transferase from three species of Leishmania using synthetic acceptor substrate analogues. Biochemistry 39, 8017-8025. (Pubitemid 30452376)
    • (2000) Biochemistry , vol.39 , Issue.27 , pp. 8017-8025
    • Routier, F.H.1    Higson, A.P.2    Ivanova, I.A.3    Ross, A.J.4    Tsvetkov, Y.E.5    Yashunsky, D.V.6    Bates, P.A.7    Nikolaev, A.V.8    Ferguson, M.A.J.9
  • 29
    • 0026752091 scopus 로고
    • Biosynthesis of lipophosphoglycan from Leishmania donovani: Characterization of mannosylphosphate transfer in vitro
    • Carver, M. A., and Turco, S. J. (1992) Biosynthesis of lipophosphoglycan from Leishmania donovani: characterization of mannosylphosphate transfer in vitro. Arch. Biochem. Biophys. 295, 309-317.
    • (1992) Arch. Biochem. Biophys. , vol.295 , pp. 309-317
    • Carver, M.A.1    Turco, S.J.2
  • 30
    • 33744980906 scopus 로고    scopus 로고
    • Parasite glycoconjugates. Part 16: Synthesis of a disaccharide and phosphorylated di- and tri-saccharides from Leishmania lipophosphoglycan
    • DOI 10.1016/j.carres.2006.03.026, PII S0008621506001479
    • Ross, A. J., Sizova, O. V., and Nikolaev, A. V. (2006) Synthesis of a disaccharide and phosphorylated di- and tri-saccharides from Leishmania lipophosphoglycan. Carbohydr. Res. 341, 1954-1964. (Pubitemid 43866032)
    • (2006) Carbohydrate Research , vol.341 , Issue.11 , pp. 1954-1964
    • Ross, A.J.1    Sizova, O.V.2    Nikolaev, A.V.3
  • 31
    • 0346100754 scopus 로고
    • Chemical synthesis of disaccharide and phosphorylated oligosaccharide fragments of Leishmania donovani antigenic lipophosphoglycan
    • Perkin Trans.
    • Nikolaev, A. V., Rutherford, T. J., Ferguson, M. A. J., and Brimacombe, J. S. (1995) Chemical synthesis of disaccharide and phosphorylated oligosaccharide fragments of Leishmania donovani antigenic lipophosphoglycan. J. Chem. Soc., Perkin Trans. 1 1977-1987.
    • (1995) J. Chem. Soc , vol.1 , pp. 1977-1987
    • Nikolaev, A.V.1    Rutherford, T.J.2    Ferguson, M.A.J.3    Brimacombe, J.S.4
  • 32
    • 33748675089 scopus 로고    scopus 로고
    • Parasite glycoconjugates. Part 8. Chemical synthesis of a heptaglycosyl triphosphate fragment of Leishmania mexicana lipo- and proteo-phosphoglycan and of a phosphorylated trisaccharide fragment of Leishmania donovani surface lipophosphoglycan
    • Higson, A. P., Tsvetkov, Y. E., Ferguson, M. A. J., and Nikolaev, A. V. (1998) Chemical synthesis of a heptaglycosyl triphosphate fragment of Leishmania mexicana lipo- and proteo-phosphoglycan and of a phosphorylated trisaccharide fragment of Leishmania donovani surface lipophosphoglycan. J. Chem. Soc., Perkin Trans. 1 2587-2595. (Pubitemid 128759774)
    • (1998) Journal of the Chemical Society - Perkin Transactions 1 , Issue.16 , pp. 2587-2595
    • Higson, A.P.1    Tsvetkov, Y.E.2    Ferguson, M.A.J.3    Nikolaev, A.V.4
  • 33
    • 33748583481 scopus 로고    scopus 로고
    • Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan
    • Nikolaev, A. V., Rutherford, T. J., Ferguson, M. A. J., and Brimacombe, J. S. (1996) Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani lipophosphoglycan. J. Chem. Soc., Perkin Trans. 1 1559-1566. (Pubitemid 126790722)
    • (1996) Journal of the Chemical Society - Perkin Transactions 1 , Issue.13 , pp. 1559-1566
    • Nikolaev, A.V.1    Rutherford, T.J.2    Ferguson, M.A.J.3    Brimacombe, J.S.4
  • 34
    • 15944389847 scopus 로고    scopus 로고
    • Synthetic fragments of antigenic lipophosphoglycans from Leishmania major and Leishmania mexicana and their use for characterisation of the Leishmania elongating α-D-mannopyranosylphosphate transferase
    • DOI 10.1002/chem.200400563
    • Higson, A. P.,Ross,A. J.,Tsvetkov,Y. E.,Routier, F.H., Sizova,O.V., Ferguson,M.A. J., andNikolaev, A. V. (2005) Synthetic fragments of antigenic lipophosphoglycan from Leishmania major and Leishmania mexicana and their use for characterization of the Leishmania elongating R-D-mannopyranosylphosphate transferase. Chem.-Eur. J. 11, 2019-2030. (Pubitemid 40446002)
    • (2005) Chemistry - A European Journal , vol.11 , Issue.7 , pp. 2019-2030
    • Higson, A.P.1    Ross, A.J.2    Tsvetkov, Y.E.3    Routier, F.H.4    Sizova, O.V.5    Ferguson, M.A.J.6    Nikolaev, A.V.7
  • 35
    • 0035974418 scopus 로고    scopus 로고
    • Synthesis of β-D-Galp-(1 →4)-α-D-Manp methanephosphonate, a substrate analogue for the elongating α-D-mannosyl phosphate transferase in the Leishmania
    • DOI 10.1016/S0040-4039(01)00961-3, PII S0040403901009613
    • Borodkin, V. S., Ferguson, M. A. J., and Nikolaev, A. V. (2001) Synthesis of β-D-Galp-(1f4)-R-D-Manp methanephosphonate, a substrate analogue for the elongating R-D-mannosyl phosphate transferase in the Leishmania. Tetrahedron Lett. 42, 5305-5308. (Pubitemid 32635153)
    • (2001) Tetrahedron Letters , vol.42 , Issue.31 , pp. 5305-5308
    • Borodkin, V.S.1    Ferguson, M.A.J.2    Nikolaev, A.V.3
  • 36
    • 0037152272 scopus 로고    scopus 로고
    • Synthesis of oligomeric phosphono analogues of Leishmania lipophosphoglycan fragments
    • Borodkin, V. S., Milne, F. C., Ferguson, M. A. J., and Nikolaev, A. V. (2002) Synthesis of oligomeric phosphono analogues of Leishmania lipophosphoglycan fragments. Tetrahedron Lett. 43, 7821-7825.
    • (2002) Tetrahedron Lett. , vol.43 , pp. 7821-7825
    • Borodkin, V.S.1    Milne, F.C.2    Ferguson, M.A.J.3    Nikolaev, A.V.4
  • 37
    • 0029761956 scopus 로고    scopus 로고
    • Characterization of lipophosphoglycan from a ricin-resistant mutant of Leishmania major
    • Opat, A., Ng, K. F., Handman, E., and Bacic, A. (1996) Characterization of lipophosphoglycan from a Ricin-resistant mutant of Leishmania major. Glycobiology 6, 387-397. (Pubitemid 26281040)
    • (1996) Glycobiology , vol.6 , Issue.4 , pp. 387-397
    • Opat, A.1    Ng, K.2    Currie, G.3    Handman, E.4    Bacic, A.5
  • 38
    • 0034175620 scopus 로고    scopus 로고
    • Application of MPEG soluble polymer support in the synthesis of oligo- phosphosaccharide fragments from the Leishmania lipophosphoglycan
    • DOI 10.1016/S0040-4039(00)00153-2, PII S0040403900001532
    • Ross, A. J., Ivanova, I. A., Higson, A. P., and Nikolaev, A. V. (2000) Application of MPEG soluble polymer support in the synthesis of oligo-phosphosaccharide fragments from the Leishmania lipophosphoglycan. Tetrahedron Lett. 41, 2449-2452. (Pubitemid 30217083)
    • (2000) Tetrahedron Letters , vol.41 , Issue.14 , pp. 2449-2452
    • Ross, A.J.1    Ivanova, I.A.2    Higson, A.P.3    Nikolaev, A.V.4
  • 39
    • 33749946901 scopus 로고
    • Colorimetric method for determination of sugars and related substances
    • Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., and Smith, F. (1956) Colorimetric method for determination of sugars and related substances. Anal. Chem. 28, 350-356.
    • (1956) Anal. Chem. , vol.28 , pp. 350-356
    • Dubois, M.1    Gilles, K.A.2    Hamilton, J.K.3    Rebers, P.A.4    Smith, F.5
  • 40
    • 0025211779 scopus 로고
    • Quantitation of protein
    • DOI 10.1016/0076-6879(90)82008-P
    • Stoscheck, C. M. (1990) Quantitation of protein. Methods Enzymol. 182, 50-68. (Pubitemid 20154379)
    • (1990) Methods in Enzymology , vol.182 , pp. 50-68
    • Stoscheck, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.