Understanding the nature of early HCV RNA blips and the use of mathematical modeling of viral kinetics during IFN-based therapy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 29, 2011, Pages

  Guedj, Jeremie ^a   Dahari, Harel ^a,b   Perelson, Alan S ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEGINTERFERON ALPHA; RIBAVIRIN; VIRUS RNA;

ANTIVIRAL THERAPY; DRUG RESPONSE; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; KINETICS; LETTER; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; VIRAL CLEARANCE; VIRION; VIRUS LOAD;

HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERON-ALPHA; KINETICS; MODELS, BIOLOGICAL; RIBAVIRIN; RNA, VIRAL; TAIWAN; VIRAL LOAD;

HEPATITIS C VIRUS;

EID: 79961034813     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1104149108     Document Type: Letter

References (5)

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4. Guedj J, Rong L, Dahari H, Perelson AS (2010) A perspective on modelling hepatitis C virus infection. J Viral Hepat 17:825-833.
5. Klatt NR, et al. (2010) CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells. PLoS Pathog 6:e1000747.