The effect of pharmacological treatment on ADMA in patients with heart failure

Frontiers in Bioscience - Elite

Volumn 3 E, Issue 4, 2011, Pages 1310-1314

  Riccioni, Graziano ^a   Speranza, Lorenza ^b   Scotti, Luca ^c   Bucciarelli, Valentina ^c   Ilio, Emanuela Di ^c   D'Orazio, Nicolantonio ^c   Pesce, Mirko ^b   Aceto, Antonio ^c   Sorrenti, Valeria ^d   Frigiola, Alessandro ^e   Bucciarelli, Tonino ^c  

^a SAN CAMILLO DE LELLIS HOSPITAL   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c University Hospital of Chieti   (Italy)

^d UNIVERSITY OF CATANIA   (Italy)

^e IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

ADMA; Asymmetric dimethylarginine; Heart failure; Pulmonary oedema

Indexed keywords

6 N,N' DIMETHYLARGININE; ANGIOTENSIN RECEPTOR ANTAGONIST; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; GLYCERYL TRINITRATE; N(G),N(G) DIMETHYLARGININE; ARGININE; DRUG DERIVATIVE; N,N DIMETHYLARGININE; N,N-DIMETHYLARGININE;

ACUTE HEART FAILURE; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONGESTIVE HEART FAILURE; CRITICALLY ILL PATIENT; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTENSIVE CARE; MALE; NEW YORK HEART ASSOCIATION CLASS; BLOOD; HEART FAILURE; MIDDLE AGED;

AGED; ARGININE; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED;

EID: 79960991697     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/e334     Document Type: Article

References (36)

1. A. J. Cardounel, J. L. Zweier: Endogenous methylarginines regulate neuronal nitric. oxide synthase and prevent excitotoxic injury. J Biol Chem 277, 33995-34002 (2002)
2. P. Vallance, A. Leone, A. Calver, J. Collier, S. Moncada: Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339, 572-575 (1992)
3. M. T. Bedford, S. G. Clarke: Protein arginine methylation in mammals: who, what, and why. Mol Cell 33, 1-13 (2009)
4. R. H. Böger: The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor. Cardiovas Res 59, 824-833 (2003) (Pubitemid 38366238)
5. T. Nicholson, T. Chen, S. Richard: The role of protein arginine methylation in normal and diseased cells. Pharmacol Res 60, 466-474 (2009)
6. C. T. Tran, M. P. Fox, P. Vallance, J. N. Leiper: Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68, 101-105 (2000)
7. R. H. Böger: Asymmetric dimethylarginine (ADMA): a novel risk marker in cardiovascular medicine and beyond. Ann Med 38, 126-136 (2006)
8. A. Ito, P. S. Tsao, S. Adimoolam, M. Kimoto, T. Ogawa, J. P. Cooke: Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation 99, 3092-3095 (1999) (Pubitemid 29289071)
9. V. Sorrenti, F. Mazza, A. Campisi, L. Vanella, G. Li Volti, C. Di Giacomo: High glucose. mediated imbalance of nitric oxide synthase and dimethylarginine dimethylaminohydrolase expression in endothelial cells. Curr Neurovasc Res 3, 49-54 (2006)
10. K. Y. Lin, A. Ito, T. Asagami, P. S. Tsao, S. Adimoolam, M. Kimoto, H. Tsuji, G. M. Reaven, J. P. Cooke: Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 20, 987-992 (2002) (Pubitemid 34925335)
11. S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats: 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. J Am Coll Cardiol 53, 1-90 (2009)
12. [No author listed]: Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Lancet 342, 821-828 (1993)
13. J. G. Cleland, K. Swedberg, F. Follath, M. Komajda, A. Cohen. Solal, J. C. Aguilar, R. Dietz, A. Gavazzi, R. Hobbs, J. Korewicki, H. C. Madeira, V. S. Moiseyev, I. Preda, W. H. Van Gilst, J. Widimsky, N. Freemantle, J. Eastaugh, J. Mason, Study Group on Diagnosis of the Working Group on Heart Failure of the European Society of Cardiology: The EuroHeart Failure survey programme - a survey on the quality of care among patients with heart failure in Europe-Part 1: patient characteristics and diagnosis. Eur Heart J 24, 442-463 (2003). (Pubitemid 36286187)
14. M. Saitoh, T. Osanai, T. Kamada, T. Matsunaga, H. Ishizaka, H. Hanada, K. Okumura. High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. Heart Vessel 18, 177-182 (2003) (Pubitemid 37258670)
15. M. Usui, H. Matsuoka, H. Miyazaki, S. Ueda, S. Okuda, T: Imaizumi. Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure. Life Sci 62, 2425-2430 (2007)
16. J. T. Kielstein, S. M. Bode. Boger, G. Klein, S. Graf, H. Haller, D. Fliser: Endogenous nitric oxide synthase inhibitors and renal perfusion in patients with heart failure. Eur J Clin Invest 33, 370-375 (2003) (Pubitemid 36583703)
17. T. Teerlink, R. J. Nijveldt, S. De Jong, P. A. Van Leeuwen: Determination of Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma and Other Biological Samples by High. Performance Liquid Chromatography. Anal Biochem 303, 131-137 (2002) (Pubitemid 34407576)
18. S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats: ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation 112, 154-235 (2005)
19. D. Lloyd. Jones, R. Adams, M. Carnethon, G. De Simone, T. B. Ferguson, K. Flegal, E. Ford, K. Furie, A. Go, K. Greenlund, N. Haase, S. Hailpern, M. Ho, V. Howard, B. Kissela, S. Kittner, D. Lackland, L. Lisabeth, A. Marelli, M. McDermott, J. Meigs, D. Mozaffarian, G. Nichol, C. O'Donnell, V. Roger, W. Rosamond, R. Sacco, P. Sorlie, R. Stafford, J. Steinberger, T. Thom, S. Wasserthiel. Smoller, N. Wong, J. Wylie. Rosett, Y. Hong, American Heart Association Statistics Committee and Stroke Statistics Subcommittee: Heart disease and stroke statistics. 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119, 480-486 (2009)
20. G. Cotter, G. M. Felker, K. F. Adams, O. Milo. Cotter, C. M. O'Connor: The pathophysiology of acute heart failure. is it all about fluid accumulation? Am Heart J 155, 9-18 (2008) (Pubitemid 350234787)
21. A. Onwuanyi, M. Taylor: Acute decompensated heart failure: pathophysiology and treatment. Am J Cardiol 99, 25-30 (2007)
22. R. J. Nijveldt, M. P. Siroen, T. Teerlink, P. A. Van Leeuwen: Elimination of asymmetric dimethylarginine by the kidney and the liver: a link to the development of multiple organ failure? J Nutr 134, 2848-2452 (2004)
23. R. J. Nijveldt, T. Teerlink, P. A. Van Leeuwen. The asymmetrical dimethylarginine (ADMA). multiple organ failure hypothesis. Clin Nutr 22, 99-104 (2003) (Pubitemid 36193187)
24. T. Osanai, M. Saitoh, S. Sasaki, H. Tomita, T. Matsunaga, K. Okumura: Effect of shear stress on asymmetric dimethylarginine release from vascular endothelial cells. Hypertension 42, 985-990 (2003) (Pubitemid 37413742)
25. K. Sydow, T. Münzel: ADMA and oxidative stress. Atherosclerosis 4, 41-51 (2003) (Pubitemid 38234494)
26. N. Rawal, R. Rajpurohit, M. A. Lischwe, K. R. Williams, W. K. Paik, S. Kim: Structural specificity of substrate for S. adenosylmethionine: protein arginine N. methyltransferases. Biochim Biophy Acta 1248, 11-18 (1995)
27. R. H. Böger, S. M. Bode. Böger, A. Szuba, P. S. Tsao, J. R. Chan, O. Tangphao, T. F. Blaschke, J. P. Cook: Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 98, 1842-1487 (2002)
28. P. Lundman, M. J. Eriksson, M. Stuhlinger, J. P. Cooke, A. Hamsten, P. Tornvall: Mild. to. moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine. J Am Coll Cardiol 38, 111-116 (2001) (Pubitemid 32613836)
29. H. Paiva, T. Lehtimaki, J. Laaks, I. Ruokonen, V. Rantalaiho, O. Wirta, A. Pasternack, R. Laaksonen: Plasma concentrations of asymmetric. dimethyl. arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy. Metabolism 52, 303-307 (2003) (Pubitemid 36406325)
30. H. M. Eid, H. Arnesen, E. M. Hjerkinn, T. Lyberg, I. Seljeflot: Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine. Metabolism 53, 1574-1579 (2004) (Pubitemid 39556372)
31. M. C. Stuhlinger, R. K. Oka, E. E. Graf, I. Schmolzer, B. M. Upson, O. Kapoor, A. Szuba, M. R. Malinow, T. C. Wascher, O. Pachinger, J. P. Cooke: Endothelial dysfunction induced by hyperhomocyst (e) inemia: role of asymmetric dimethylarginine. Circulation 108, 933-938 (2003) (Pubitemid 37048221)
32. M. C. Stuhlinger, P. S. Tsao, J. H. Her, M. Kimoto, R. F. Balint, J. P. Cooke: Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation 104, 2569-2575 (2001) (Pubitemid 33104795)
33. D. P. Holden, J. E. Cartwright, S. S. Nussey, G. S. Whitley: Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. Circulation 108, 1575-1580 (2003) (Pubitemid 37187783)
34. K. B. Holven, T. S. Haugstad, T. Holm, P. Aukrust, L. Ose, M. S. Nenseter: Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects. Br J Nutr 89, 359-363 (2003) (Pubitemid 36422777)
35. C. Hottelart, N. El Esper, F. Rose, J. M. Achard, A. Fournier: Fenofibrate increases creatininemia by increasing metabolic production of creatinine. Nephron 92, 536-541 (2002)
36. J. Betowski, A. Kêdra: Asymmetric dimethylarginine (ADMA) as a target for pharmacotherapy. Pharmacol Rep 58, 159-178 (2006)