Construction and identification of mammary expressional vector for cDNA of human lactoferrin

Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology

Volumn 27, Issue 2, 2011, Pages 253-261

  Meng, Li ^a   Zhang, Yanli ^a   Xu, Xin ^a   Wang, Ziyu ^a   Yan, Yibo ^a   Pang, Xunsheng ^a   Zhong, Bushuai ^a   Huang, Rong ^a   Song, Yang ^a   Wang, Jinyu ^b   Wang, Feng ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

Biological function; C127 cells; GMC cells; Human lactoferrin; PBC1 hLF Neo

Indexed keywords

CASEIN; COMPLEMENTARY DNA; LACTOFERRIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; GOAT; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROMOTER REGION; TUMOR CELL LINE; UDDER;

ANIMALS; BASE SEQUENCE; BREAST NEOPLASMS; CASEINS; CELL LINE, TUMOR; DNA, COMPLEMENTARY; EPITHELIAL CELLS; FEMALE; GENETIC VECTORS; GOATS; HUMANS; LACTOFERRIN; MAMMARY GLANDS, ANIMAL; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PROMOTER REGIONS, GENETIC;

BACTERIA (MICROORGANISMS); CAPRA HIRCUS; ESCHERICHIA COLI;

EID: 79960987497     PISSN: 10003061     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Waarts B L, Onwuchekwa J C, Smit J M, et al. Antiviral activity of human lactoferrin: inhibition of alphavirus interaction with heparin sulfate. Virology, 2005, 333(2): 284-292.
2. Lonnerdal B, Bryantthe A. Absorption of iron from recombinant human lactoferrin in young US women. Am J Clin Nutr, 2006, 83(2): 305-309.
3. Varadhachary A. Wolf J S, Petrak K, et al. Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy. Int J Cancer, 2004, 111(3): 398-403.
4. Berlov M N, Korableva E S, Andreeva Y V, et al. Lactoferrin from canine neutrophils: isolation and physicochemical and antimicrobial properties. Biochemistry, 2007, 72(4): 445-451.
5. Wilk K M, Hwang S A, Actor J K. Lactoferrin modulation of antigen-presenting-cell response to BCG infection. Postepy Hig Med Dosw, 2007, 61(1): 277-282.
6. Yuan Y G, Ding G L, Cheng Y, et al. Production of cloned goats by transfer of nuclei from transfected caprine mammary gland epithelial cells. Chin J Biotech, 2009, 25(8): 1138-1143.
7. Naot D, Grey A, Reid I R, et al. Lactoferrin-a novel bone growthfactor. Clin Med Res, 2005, 3: 93-101.
8. Saidi V H, Eslahpazir J, Carbonneil C, et al. Differential modulation of human lactoferrin activity against both R5 and X4-HIV-1 adsorption on epithelial cells and dendritic cells by natural antibodies. J Immunol, 2006, 177(20): 5540-5549.
9. Wolf J S, Li G, Varadhachary A, et al. Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo. Clin Cancer Res, 2007, 13(5): 1601-1610.
10. Paesano R, Torcia F, Berlutti V, et al. Oral administration of lactoferrin increases hemoglobin andtotal serum iron in pregnant women. Biochem Cell Biol, 2006, 84(3): 377-380.
11. Liang Q W, Richardson T. Expression and characterization of human lactoferrin in yeast Saccharomyces cerevisiae. J Agric Food Chem, 1993, 41(10): 1800-1807.
12. Zhang J, Li L, Cai Y, et al. Expression of active recombinant human lactoferrin in the milk of transgenic goats. Protein Expr Purif, 2008, 57: 127-135.
13. Sambrook J, Fritsh E F, Maniatis T. Molecular Clonging: A Laboratory Manual. 2nd ed. New York: Cold Spring Harbor Laboratory Press, 1989.
14. Zhao M T, Lin H, Liu F J, et al. Efficiency of human lactoferrin transgenic donor cell preparation for SCNT. Theriogenology, 2009, 71: 376-384.
15. He Z Y, Yu S L, Li N, et al. Maternally transmitted milk containing recombinant human catalase provides protection against oxidation for mouse offspring during lactation. Free Radical BIO MED, 2008, 45: 1135-114.
16. Zhang Y L, Wan Y J, Wang F, et al. Production of dairy goat embryos, by nuclear transfer, transgenic for human acid β-glucosidase. Theriogenology, 2010, 73(5): 681-690.
17. Robert E, Rhoads, Ewa G N. Translational regulation of milk protein synthesis at secretory activation. J Mammary Gland Bio Neoplasia, 2007, 12: 283-292.
18. Cao Y, Gao H Y, Yu L, et al. Studies of the clone and cell expression of human lactoferrin gene. Hereditas, 2002, 24(1): 9-14.
19. Van Berkel P H, Welling M M, Geerts M, et al. Large scale production of recombinant human lactoferrin in the milk of transgenic cows. Nat Biotechnol, 2002, 20(5): 484-487.
20. Yang P H, Wang J W, Li N, et al. Cattle mammary bioreactor generated by a novel procedure of transgenic cloning for large-scale production of functional human Lactoferrin. PLoS One, 2008, 3(10): e3453.