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Volumn 6, Issue 5, 2011, Pages 803-814

Layered double hydroxide nanoparticles as target-specific delivery carriers: Uptake mechanism and toxicity

Author keywords

layered double hydroxide; uptake behaviors; uptake mechanism toxicity

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; HYDROTALCITE; HYDROXIDE; LAYERED DOUBLE HYDROXIDE; METHOTREXATE; NANOCARRIER; NANOPARTICLE; UNCLASSIFIED DRUG;

EID: 79960966253     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.11.86     Document Type: Review
Times cited : (185)

References (52)
  • 2
    • 0026414766 scopus 로고
    • Hydrotalcite-type anionic clays: Preparation properties and applications
    • Cavani F, Trifiro F, Vaccari A. Hydrotalcite-type anionic clays: preparation, properties and applications. Catal. Today 11, 173-301 (1991).
    • (1991) Catal. Today , vol.11 , pp. 173-301
    • Cavani, F.1    Trifiro, F.2    Vaccari, A.3
  • 3
    • 33645464531 scopus 로고    scopus 로고
    • Preparation of layered double hydroxides and their applications as additives in polymers as precursors to magnetic materials and in biology and medicine
    • Evans DG, Duan X. Preparation of layered double hydroxides and their applications as additives in polymers, as precursors to magnetic materials and in biology and medicine. Chem. Commun. 485-496 (2006).
    • (2006) Chem. Commun. , pp. 485-496
    • Evans, D.G.1    Duan, X.2
  • 7
    • 85047700235 scopus 로고    scopus 로고
    • Organo-modified anionic clays into polymer compared to smectite-type nanofiller: Potential applications of the nanocomposites
    • DOI 10.1166/jnn.2006.003
    • Leroux F. Organo-modified anionic clays into polymer compared with smectite-type nanofiller: potential applications of the nanocomposites. J. Nanosci. Nanotechnol. 6, 303-315 (2006). (Pubitemid 44576185)
    • (2006) Journal of Nanoscience and Nanotechnology , vol.6 , Issue.2 , pp. 303-315
    • Leroux, F.1
  • 8
    • 33947175972 scopus 로고    scopus 로고
    • Clay minerals and layered double hydroxides for novel biological applications
    • DOI 10.1016/j.clay.2006.07.007, PII S0169131706001517
    • Choy JH, Choi SJ, Oh JM, Park T. Clay minerals and layered double hydroxides for novel biological applications. Appl. Clay Sci. 36, 122-132 (2007). (Pubitemid 46414158)
    • (2007) Applied Clay Science , vol.36 , Issue.1-3 , pp. 122-132
    • Choy, J.-H.1    Choi, S.-J.2    Oh, J.-M.3    Park, T.4
  • 9
    • 70249088739 scopus 로고    scopus 로고
    • Layered double hydroxide nanoparticles in gene and drug delivery
    • Ladewig K, Xu ZP, Lu GQ. Layered double hydroxide nanoparticles in gene and drug delivery. Expert. Opin. Drug Deliv. 6, 907-922 (2009).
    • (2009) Expert. Opin. Drug Deliv. , vol.6 , pp. 907-922
    • Ladewig, K.1    Xu, Z.P.2    Lu, G.Q.3
  • 11
    • 27844445222 scopus 로고    scopus 로고
    • Inorganic nanoparticles as carriers for efficient cellular delivery
    • DOI 10.1016/j.ces.2005.06.019, PII S0009250905005609, Biomolecular Engineering
    • Xu ZP, Zeng QH, Lu GQ, Yu AB. Inorganic nanoparticles as carriers for efficient cellular delivery. Chem. Eng. Sci. 61, 1027-1040 (2006). (Pubitemid 41650188)
    • (2006) Chemical Engineering Science , vol.61 , Issue.3 , pp. 1027-1040
    • Xu, Z.P.1    Hua Zeng, Q.2    Lu, G.Q.3    Bing Yu, A.4
  • 12
    • 43449117484 scopus 로고    scopus 로고
    • Anticancer drug-layered double hydroxide nanohybrids as potent cancer chemotherapy agents
    • Choi SJ, Oh JM, Choy JH. Anticancer drug-layered double hydroxide nanohybrids as potent cancer chemotherapy agents. J. Phys. Chem. Solids 69, 1528-1532 (2008).
    • (2008) J. Phys. Chem. Solids , vol.69 , pp. 1528-1532
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 13
    • 77952754523 scopus 로고    scopus 로고
    • Biocompatible nanoparticles intercalated with anticancer drug for target delivery: Pharmacokinetic and biodistribution study
    • Choi SJ, Oh JM, Choy JH. Biocompatible nanoparticles intercalated with anticancer drug for target delivery: pharmacokinetic and biodistribution study. J. Nanosci. Nanotechnol. 10, 2913-2916 (2010).
    • (2010) J. Nanosci. Nanotechnol. , vol.10 , pp. 2913-2916
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 14
    • 1142309719 scopus 로고    scopus 로고
    • Layered double hydroxide as an efficient drug reservoir for folate derivatives
    • DOI 10.1016/j.biomaterials.2003.09.083
    • Choy JH, Jung JS, Oh JM, Park M, Jeong J, Kang YK, Han OJ. Layered double hydroxide as an efficient drug reservoir for folate derivatives. Biomaterials 25, 3059-3064 (2004). (Pubitemid 38210198)
    • (2004) Biomaterials , vol.25 , Issue.15 , pp. 3059-3064
    • Choy, J.-H.1    Jung, J.-S.2    Oh, J.-M.3    Park, M.4    Jeong, J.5    Kang, Y.-K.6    Han, O.-J.7
  • 16
    • 0034995867 scopus 로고    scopus 로고
    • Cellular uptake behavior of γ-P-32 labeled ATP-LDH nanohybrids
    • Choy JH, Kwak SY, Park JS, Jeong YJ. Cellular uptake behavior of [g-P-32] labeled ATP-LDH nanohybrids. J. Mater. Chem. 11, 1671-1674 (2001).
    • (2001) J. Mater. Chem. , vol.11 , pp. 1671-1674
    • Choy, J.H.1    Kwak, S.Y.2    Park, J.S.3    Jeong, Y.J.4
  • 18
    • 1642421165 scopus 로고    scopus 로고
    • Intercalation of vitamer into LDH and their controlled release properties
    • Choy JH, Son YH. Intercalation of vitamer into LDH and their controlled release properties. Bull. Kor. Chem. Soc. 25, 122-126 (2004).
    • (2004) Bull. Kor. Chem. Soc. , vol.25 , pp. 122-126
    • Choy, J.H.1    Son, Y.H.2
  • 21
    • 66449121155 scopus 로고    scopus 로고
    • Inorganic drug-delivery nanovehicle conjugated with cancer-cell-specific ligand
    • Oh JM, Choi SJ, Lee GE, Han SH, Choy JH. Inorganic drug-delivery nanovehicle conjugated with cancer-cell-specific ligand. Adv. Funct. Mater. 19, 1-8 (2009).
    • (2009) Adv. Funct. Mater. , vol.19 , pp. 1-8
    • Oh, J.M.1    Choi, S.J.2    Lee, G.E.3    Han, S.H.4    Choy, J.H.5
  • 22
    • 77957302583 scopus 로고    scopus 로고
    • Efficient delivery of siRNA to cortical neurons using layered double hydroxide nanoparticles
    • Wong Y, Markham K, Xu ZP et al. Efficient delivery of siRNA to cortical neurons using layered double hydroxide nanoparticles. Biomaterials 31, 8770-8779 (2010).
    • (2010) Biomaterials , vol.31 , pp. 8770-8779
    • Wong, Y.1    Markham, K.2    Xu, Z.P.3
  • 23
    • 33845188629 scopus 로고    scopus 로고
    • Cellular uptake mechanism of an inorganic nanovehicle and its drug conjugates: Enhanced efficacy due to clathrin-mediated endocytosis
    • Oh JM, Choi SJ, Kim ST, Choy JH. Cellular uptake mechanism of an inorganic nanovehicle and its drug conjugates: enhanced efficacy due to clathrin-mediated endocytosis. Bioconjug. Chem. 17, 1411-1417 (2006).
    • (2006) Bioconjug. Chem. , vol.17 , pp. 1411-1417
    • Oh, J.M.1    Choi, S.J.2    Kim, S.T.3    Choy, J.H.4
  • 24
    • 38849122650 scopus 로고    scopus 로고
    • Human-related application and nanotoxicology of inorganic particles: Complementary aspects
    • Choi SJ, Oh JM, Choy JH. Human-related application and nanotoxicology of inorganic particles: complementary aspects. J. Mater. Chem. 18, 615-620 (2008).
    • (2008) J. Mater. Chem. , vol.18 , pp. 615-620
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 25
    • 8144230247 scopus 로고    scopus 로고
    • Flow cytometry: Interesting tool for studying binding behavior of DNA on inorganic layered double hydroxide (LDH)
    • DOI 10.1002/cyto.a.20085
    • Burzlaff A, Brethauer S, Kasper C, Jackisch BO, Scheper T. Flow cytometry: interesting tool for studying binding behavior of DNA on inorganic layered double hydroxide (LDH).Cytometry A 62, 65-69 (2004). (Pubitemid 39473455)
    • (2004) Cytometry Part A , vol.62 , Issue.1 , pp. 65-69
    • Burzlaff, A.1    Brethauer, S.2    Kasper, C.3    Jackisch, B.-O.4    Scheper, T.5
  • 27
    • 48749110647 scopus 로고    scopus 로고
    • Subcellular compartment targeting of layered double hydroxide nanoparticles
    • Xu ZP, Niebert M, Porazik K et al. Subcellular compartment targeting of layered double hydroxide nanoparticles. J. Control. Release 130, 86-94 (2008).
    • (2008) J. Control. Release , vol.130 , pp. 86-94
    • Xu, Z.P.1    Niebert, M.2    Porazik, K.3
  • 28
    • 2342533902 scopus 로고    scopus 로고
    • Cell response to dextran-derivatised iron oxide nanoparticles post internalisation
    • DOI 10.1016/j.biomaterials.2003.12.046, PII S0142961203012183
    • Berry CC, Wells S, Charles S, Aitchison G, Curtis AS. Cell response to dextran-derivatised iron oxide nanoparticles post internalisation. Biomaterials 25, 5405-5413 (2004). (Pubitemid 38586755)
    • (2004) Biomaterials , vol.25 , Issue.23 , pp. 5405-5413
    • Berry, C.C.1    Wells, S.2    Charles, S.3    Aitchison, G.4    Curtis, A.S.G.5
  • 29
    • 77952754524 scopus 로고    scopus 로고
    • Uptake of functionalized mesoporous silica nanoparticles by human cancer cells
    • Fisichella M, Dabboue H, Bhattacharyya S et al. Uptake of functionalized mesoporous silica nanoparticles by human cancer cells. J. Nanosci. Nanotechnol. 10, 2314-2324 (2010).
    • (2010) J. Nanosci. Nanotechnol. , vol.10 , pp. 2314-2324
    • Fisichella, M.1    Dabboue, H.2    Bhattacharyya, S.3
  • 30
    • 31044442114 scopus 로고    scopus 로고
    • Carbon nanotubes as intracellular transporters for proteins and DNA: An investigation of the uptake mechanism and pathway
    • DOI 10.1002/anie.200503389
    • Kam NW, Liu Z, Dai H. Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway. Angew. Chem. Int. Ed. Engl. 45, 577-581 (2006). (Pubitemid 43121447)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.4 , pp. 577-581
    • Kam, N.W.S.1    Liu, Z.2    Dai, H.3
  • 31
    • 17744390893 scopus 로고    scopus 로고
    • Carbon nanotubes as intracellular protein transporters: Generality and biological functionality
    • DOI 10.1021/ja050062v
    • Kam NWS, Dai HJ. Carbon nanotubes as intracellular protein transporters: generality and biological functionality. J. Am. Chem. Soc. 127, 6021-6026 (2005). (Pubitemid 40577658)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.16 , pp. 6021-6026
    • Kam, N.W.S.1    Dai, H.2
  • 32
    • 75949123233 scopus 로고    scopus 로고
    • Physicochemical properties affecting cellular uptake of carbon nanotubes
    • Lond
    • Raffa V, Ciofani G, Vittorio O, Riggio C, Cuschieri A. Physicochemical properties affecting cellular uptake of carbon nanotubes. Nanomedicine (Lond.) 5, 89-97 (2010).
    • (2010) Nanomedicine , vol.5 , pp. 89-97
    • Raffa, V.1    Ciofani, G.2    Vittorio, O.3    Riggio, C.4    Cuschieri, A.5
  • 33
    • 79952745367 scopus 로고    scopus 로고
    • Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells
    • Thurn KT, Arora H, Paunesku T et al. Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells. Nanomedicine 7, 123-130 (2011).
    • (2011) Nanomedicine , vol.7 , pp. 123-130
    • Thurn, K.T.1    Arora, H.2    Paunesku, T.3
  • 34
    • 58149193395 scopus 로고    scopus 로고
    • Inorganic metal hydroxide nanoparticles for targeted cellular uptake through clathrin-mediated endocytosis
    • Oh JM, Choi SJ, Lee GE, Kim JE, Choy JH. Inorganic metal hydroxide nanoparticles for targeted cellular uptake through clathrin-mediated endocytosis. Chem. Asian J. 4, 67-73 (2009).
    • (2009) Chem. Asian J. , vol.4 , pp. 67-73
    • Oh, J.M.1    Choi, S.J.2    Lee, G.E.3    Kim, J.E.4    Choy, J.H.5
  • 35
    • 58149235689 scopus 로고    scopus 로고
    • Safety aspect of inorganic layered nanoparticles: Size-dependency in vitro and in vivo
    • Choi SJ, Oh JM, Choy JH. Safety aspect of inorganic layered nanoparticles: size-dependency in vitro and in vivo. J. Nanosci. Nanotechnol. 8, 5297-5301 (2008).
    • (2008) J. Nanosci. Nanotechnol. , vol.8 , pp. 5297-5301
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 37
    • 78049255413 scopus 로고    scopus 로고
    • Anticancer drug encapsulated in inorganic lattice can overcome drug resistance
    • Choi SJ, Choi G, Oh JM, Oh YJ, Park MC, Choy JH. Anticancer drug encapsulated in inorganic lattice can overcome drug resistance. J. Mater. Chem. 20, 9463-9469 (2010).
    • (2010) J. Mater. Chem. , vol.20 , pp. 9463-9469
    • Choi, S.J.1    Choi, G.2    Oh, J.M.3    Oh, Y.J.4    Park, M.C.5    Choy, J.H.6
  • 38
    • 0024553681 scopus 로고
    • The folate antagonist, methotrexate, is a potent inhibitor of murine and human cytomegalovirus in vitro
    • DOI 10.1016/0166-3542(89)90012-0
    • Shanley JD, Debs RJ. The folate antagonist, methotrexate, is a potent inhibitor of murine and human cytomegalovirus in vitro. Antiviral Res. 11, 99-106 (1989). (Pubitemid 19106424)
    • (1989) Antiviral Research , vol.11 , Issue.2 , pp. 99-106
    • Shanley, J.D.1    Debs, R.J.2
  • 39
    • 0036023046 scopus 로고    scopus 로고
    • Sorting and function of the human folate receptor is independent of the caveolin expression in Fisher rat thyroid epithelial cells
    • Kim CH, Park YS, Chung KN, Elwood PC. Sorting and function of the human folate receptor is independent of the caveolin expression in Fisher rat thyroid epithelial cells. J. Biochem. Mol. Biol. 35, 395-402 (2002).
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 395-402
    • Kim, C.H.1    Park, Y.S.2    Chung, K.N.3    Elwood, P.C.4
  • 40
    • 23844477204 scopus 로고    scopus 로고
    • Folate-receptor-mediated delivery of InP quantum dots for bioimaging using confocal and two-photon microscopy
    • DOI 10.1021/ja051455x
    • Bharali DJ, Lucey DW, Jayakumar H, Pudavar HE, Prasad PN. Folate-receptor-mediated delivery of InP quantum dots for bioimaging using confocal and two-photon microscopy. J. Am. Chem. Soc. 127, 11364-11371 (2005). (Pubitemid 41176898)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.32 , pp. 11364-11371
    • Bharali, D.J.1    Lucey, D.W.2    Jayakumar, H.3    Pudavar, H.E.4    Prasad, P.N.5
  • 41
    • 67649321660 scopus 로고    scopus 로고
    • Biocompatible ceramic nanocarrier for drug delivery with high efficiency
    • Jpn
    • Choi SJ, Oh JM, Choy JH. Biocompatible ceramic nanocarrier for drug delivery with high efficiency. J. Ceram. Soc. Jpn 117, 543-549 (2009).
    • (2009) J. Ceram. Soc. , vol.117 , pp. 543-549
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 42
    • 59649103553 scopus 로고    scopus 로고
    • Toxicological effects of inorganic nanoparticles on human lung cancer A549 cells
    • Choi SJ, Oh JM, Choy JH. Toxicological effects of inorganic nanoparticles on human lung cancer A549 cells. J. Inorg. Biochem. 103, 463-471 (2009).
    • (2009) J. Inorg. Biochem. , vol.103 , pp. 463-471
    • Choi, S.J.1    Oh, J.M.2    Choy, J.H.3
  • 43
    • 0037098504 scopus 로고    scopus 로고
    • Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamine
    • DOI 10.1016/S0003-9861(02)00064-4, PII S0003986102000644
    • Dikalov SI, Dikalova AE, Mason RP. Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamine. Arch. Biochem. Biophys. 402, 218-226 (2002). (Pubitemid 34848639)
    • (2002) Archives of Biochemistry and Biophysics , vol.402 , Issue.2 , pp. 218-226
    • Dikalov, S.I.1    Dikalova, A.E.2    Mason, R.P.3
  • 44
    • 50949124960 scopus 로고    scopus 로고
    • Phospholipase A 2 reactive oxygen species and lipid peroxidation in CNS pathologies
    • Adibhatla RM, Hatcher JF. Phospholipase A(2), reactive oxygen species, and lipid peroxidation in CNS pathologies. BMB Rep. 41, 560-567 (2008).
    • (2008) BMB Rep. , vol.41 , pp. 560-567
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 45
    • 77149178395 scopus 로고    scopus 로고
    • Biological evaluation of layered double hydroxides as efficient drug vehicles
    • Li Y, Liu D, Ai H et al. Biological evaluation of layered double hydroxides as efficient drug vehicles. Nanotechnology 21, 105101 (2010).
    • (2010) Nanotechnology , vol.21 , pp. 105101
    • Li, Y.1    Liu, D.2    Ai, H.3
  • 46
    • 38449109597 scopus 로고    scopus 로고
    • Cellular toxicity of inorganic hydroxide nanoparticles
    • Choi SJ, Oh JM, Park T, Choy JH. Cellular toxicity of inorganic hydroxide nanoparticles. J. Nanosci. Nanotech. 7, 4017-4020 (2007).
    • (2007) J. Nanosci. Nanotech. , vol.7 , pp. 4017-4020
    • Choi, S.J.1    Oh, J.M.2    Park, T.3    Choy, J.H.4
  • 47
    • 18244383516 scopus 로고    scopus 로고
    • Influences of polyaromatic hydrocarbons and heavy metals on a thyroid carcinoma cell line
    • DOI 10.1248/jhs.51.202
    • Kobayashi J, Kizu R, Sugiyama H. Influence of polyaromatic hydrocarbons and heavy metals on a thyroid carcinoma cell line. J. Health Sci. 51, 202-206 (2005). (Pubitemid 40628467)
    • (2005) Journal of Health Science , vol.51 , Issue.2 , pp. 202-206
    • Kobayashi, J.1    Kizu, R.2    Sugiyama, H.3
  • 48
    • 66749110407 scopus 로고    scopus 로고
    • Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines
    • Lanone S, Rogerieux F, Geys J et al. Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines. Part. Fibre Toxicol. 6, 14 (2009).
    • (2009) Part. Fibre Toxicol. , vol.6 , pp. 14
    • Lanone, S.1    Rogerieux, F.2    Geys, J.3
  • 49
    • 38349153561 scopus 로고    scopus 로고
    • Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to zebrafish danio rerio early developmental stage
    • Zhu X, Zhu L, Duan Z, Qi R, Li Y, Lang Y. Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to Zebrafish (Danio rerio) early developmental stage. J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng. 43, 278-284 (2008).
    • (2008) J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng. , vol.43 , pp. 278-284
    • Zhu, X.1    Zhu, L.2    Duan, Z.3    Qi, R.4    Li, Y.5    Lang, Y.6
  • 51
    • 43449089199 scopus 로고    scopus 로고
    • Mechanochemical route for synthesizing nitrate form of layered double hydroxide
    • DOI 10.1016/j.powtec.2007.09.013, PII S0032591007004949
    • Tongamp W, Zhang Q, Saito F. Mechanochemical route for synthesizing nitrate form of layered double hydroxide. Powder Technol. 185, 43-48 (2008). (Pubitemid 351671812)
    • (2008) Powder Technology , vol.185 , Issue.1 , pp. 43-48
    • Tongamp, W.1    Zhang, Q.2    Saito, F.3
  • 52
    • 2942546146 scopus 로고    scopus 로고
    • Inorganic delivery vector for intravenous injection
    • DOI 10.1016/j.biomaterials.2004.01.056, PII S0142961204001115
    • Kwak SY, Kriven WM, Wallig MA, Choy JH. Inorganic delivery vector for intravenous injection. Biomaterials 25, 5995-6001 (2004). (Pubitemid 38747022)
    • (2004) Biomaterials , vol.25 , Issue.28 , pp. 5995-6001
    • Kwak, S.-Y.1    Kriven, W.M.2    Wallig, M.A.3    Choy, J.-H.4


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